Peripheral Arterial Disease News and Research

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Simple test helps predict heart attack risk

The use of common and readily available screening tests - like the ankle brachial index (ABI) - along with traditional risk scoring systems - such as the Framingham Risk Score - has the potential to prevent devastating heart attacks in thousands of individuals who are not originally thought to be at high risk (according to Framingham alone), say researchers at the Society of Interventional Radiology's 34th Annual Scientific Meeting.

11 Mar 2009

'Seeing' stem cells helps in fight against peripheral arterial disease

Interventional radiologists are fitting together the puzzle pieces of how to use stem cells to create new or more blood vessels to treat peripheral arterial disease (PAD) in those individuals with extensively narrowed or clogged arteries.

11 Mar 2009

Saving limbs with drug-eluting stents

Attempts to treat critical limb ischemia in peripheral arterial disease (PAD) patients with below-the-knee angioplasty are still thwarted by restenosis (the re-narrowing of the artery at the site of angioplasty or stenting), the need for repeat treatments and the continued progression of atherosclerotic disease, leading to tissue death (gangrene) and amputation.

11 Mar 2009

FDA approves KAPIDEX (dexlansoprazole) capsules for the treatment of GERD

Patients with leg pain caused by arterial disease may be able to forego treatment of the affected artery by participating in hospital-supervised exercise, according to a new study published in the February issue of Radiology.

2 Feb 2009

Stroke telemedicine assessed

Stroke telemedicine is a lifesaving practice that deserves further advancement, Mayo researchers write in the January 2009 issue of Mayo Clinic Proceedings.

19 Jan 2009

Two out of three Canadians not aware of peripheral arterial disease

Two out of three Canadians are not aware of peripheral arterial disease (P.A.D.), a common vascular disease that affects as many as 800,000 Canadians, according to a study published in the Canadian Journal of Cardiology.

19 Jan 2009

Treadmill exercise improves walking endurance for patients with PAD

Patients with peripheral arterial disease (PAD), which can include symptoms such as pain in the legs, who participated in supervised treadmill exercise improved their walking endurance and quality of life, according to a study in the January 14 issue of JAMA.

14 Jan 2009

Large trial on low-dose aspirin in diabetics

Type 2 diabetics treated with low-dose aspirin did not have a significantly lower incidence of atherosclerotic events than those who received placebo in this primary prevention trial of low-dose aspirin, according to research presented at the American Heart Association's Scientific Sessions 2008. However, sub-group analyses showed a significant reduction with aspirin in both atherosclerotic events in those over 65 years of age, and a reduction in cerebrocardiovascular deaths.

11 Nov 2008

Low-dose aspirin does not appear to reduce risk of CV events in patients with diabetes

Low-dose aspirin as primary prevention did not appear to significantly reduce the risk of a combined end point of coronary, cerebrovascular and peripheral vascular events in patients with type 2 diabetes, according to a new study in JAMA.

10 Nov 2008

People with diabetes lose more than money

It is not about money. No amount of money will give back my limb" said a 65 years old woman with diabetes (name withheld on request) who underwent limb amputation at the Gandhi Memorial & Associated Hospitals (GM & AH).

7 Oct 2008

Diffusion Pharmaceuticals initiates phase I/II clinical trial in patients with peripheral arterial disease

Diffusion Pharmaceuticals LLC, a clinical-stage drug-development company commercializing new drugs for the treatment of unmet medical needs, announced today that it has begun to enroll patients in a Phase I/II clinical trial of its lead drug candidate trans sodium crocetinate (TSC).

3 Sep 2008

Warning issued on dangers of diabetes drug Avandia

Thousands of Australians who are taking the diabetes drug Avandia (rosiglitazone) have been urged by the drug's manufacturer to see their doctors following safety issues concerning the medication.

20 Aug 2008

New ultrasound imaging system spots early evidence of peripheral arterial disease

Researchers at Oregon Health & Science University have devised an ultrasound imaging technique that picks up subtle early evidence of peripheral arterial disease (PAD) that current conventional tests miss.

17 Jul 2008

African Americans have five times higher rate of lower limb amputations

The overall amputation rate in northern Illinois is declining due to improved care for diabetes and peripheral vascular disease, new research shows.

28 Apr 2008

Peripheral arterial disease linked to too little vitamin D

According to the results of the latest research peripheral arterial disease (PAD) may be linked to low levels of vitamin D.

21 Apr 2008

Sexual dysfunction in postmenopausal women not linked to heart disease

Although sexual dysfunction in some men is predictive of cardiovascular disease, this association has never been examined in women.

10 Apr 2008

Sexual dissatisfaction in postmenopausal women not linked to cardiovascular disease

Although sexual dysfunction in some men is predictive of cardiovascular disease, this association has never been examined in women.

4 Apr 2008

Discovery of gene variant linked to nicotine addiction and lung cancer

Scientists have identified a genetic variant that not only makes smokers more susceptible to nicotine addiction but also increases their risk of developing two smoking-related diseases, lung cancer and peripheral arterial disease.

3 Apr 2008

Link between variant in the sequence of the human genome and susceptibility to nicotine dependence

Cigarette smoking is a major public health problem that contributes to millions of deaths around the world each year.

3 Apr 2008

Angioplasty and stenting for renal artery lesions

The largest-ever randomized study to evaluate the effectiveness of catheter-based interventions in patients with narrowing of the renal artery has shown that angioplasty and stenting offer no benefit over medical therapy.

2 Apr 2008