Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Breakthrough research could lead to new drugs to improve heart attack outcomes

A research advance from the Sanford Burnham Prebys Medical Discovery Institute and Stanford University could lead to new drugs that minimize the damage caused by heart attacks.

30 Jun 2016

Excessive weight at young age increases risk of heart failure

It comes down to starting healthy habits early. Fortunately, it's never too late to adopt a healthier lifestyle, and losing weight is great for reducing your risk of heart attack. But you can still be at a higher risk for other heart problems if you're late in changing your habits.

29 Jun 2016

MOOD-HF supports lack of antidepressant efficacy in HF patients

Escitalopram influences neither depressive symptoms nor medical outcomes when compared with placebo in patients with heart failure and depression, show the MOOD-HF findings.

29 Jun 2016

New electric mesh device wraps around the heart to deliver electrical impulses

A research team led by investigators at Beth Israel Deaconess Medical Center and Seoul National University has developed a new electric mesh device that can be wrapped around the heart to deliver electrical impulses and thereby improve cardiac function in experimental models of heart failure, a major public health concern and leading cause of mortality and disability.

29 Jun 2016

Pioglitazone effective in diabetes patients with NASH

Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows.

28 Jun 2016

Elevated troponin I should not rule out donor hearts

Donor cardiac troponin I level is not associated with intermediate-term mortality, cardiac allograft vasculopathy or primary graft failure in patients receiving heart transplants, US researchers report.

28 Jun 2016

Jefferson researchers discover alternate pathway that helps heart keep pumping

About 5.7 million Americans have heart failure, half of whom will die from the disease within 5 years, according to the Centers for Disease Control and Prevention.

28 Jun 2016

Study highlights need to improve end-of-life care for all patients with serious illnesses

Historically, efforts to improve end-of-life care have focused primarily on patients with cancer. But few studies have looked at the quality of end-of-life care for patients with other serious illnesses, such as lung, kidney or heart failure or dementia.

27 Jun 2016

Re-engineering cardiac scarring process could improve clinical outcomes for heart disease patients

Literal heartbreak, from illness or injury, triggers the body's natural healing mechanisms.

25 Jun 2016

Race impacts adverse outcomes in atrial fibrillation

Black individuals with atrial fibrillation have markedly higher rates of stroke, heart failure, coronary heart disease and mortality than their White counterparts, data from the Atherosclerosis Risk in Communities study show.

24 Jun 2016

NCX1 protein could help prevent progression of heart failure

A protein known to be crucial for maintaining the balance of calcium in cells could prove useful in halting the progression of heart failure.

24 Jun 2016

Could artificial intelligence help to combat stress? An interview with Davide Morelli

Stress is actually a bit of a buzzword. The initial definition was “the reaction to changes”, which is why you get stressed also when good things happen, hence the distinction between good stress, eustress, and bad stress, distress.

23 Jun 2016

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

A UCLA-led study estimates that almost 28,500 deaths could be prevented each year in the U.S. through use of a new FDA-approved class of cardiovascular medication that helps reduce mortality in patients diagnosed with heart failure and reduced ejection fraction, the percentage of blood pumped from the heart with each contraction.

22 Jun 2016

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease.

22 Jun 2016

New protein risk score may help predict cardiovascular risk in patients with CHD

In a study appearing in the June 21 issue of JAMA, Peter Ganz, M.D., of the University of California-San Francisco, and colleagues conducted a study to develop and validate a score to predict risk of cardiovascular outcomes among patients with coronary heart disease using analysis of circulating proteins.

21 Jun 2016

Researchers identify new myosin kinase that could optimize heart contractions

The heart is the only muscle that contracts and relaxes continuously over a lifetime to pump oxygen-rich blood to the body's organs. Researchers at UT Southwestern Medical Center now have identified a previously unrecognized enzyme that could optimize contraction and lead to new strategies to treat heart failure.

21 Jun 2016

Fixed-dose combination of sacubitril and valsartan for heart failure shows differing added benefit

The fixed-dose combination of sacubitril and valsartan (trade name: Entresto) has been approved since November 2015 for adults with symptomatic chronic heart failure with reduced pump function.

21 Jun 2016

AF patients at risk for stroke mostly treated with aspirin-only prescription instead of blood thinners

Researchers at University of California San Diego School of Medicine and University of California, San Francisco School of Medicine report that more than 1 in 3 atrial fibrillation (AF) patients at intermediate to high risk for stroke are treated with aspirin alone, despite previous data showing this therapy to be inferior to blood thinners.

21 Jun 2016

New blood test could help predict severity of pulmonary arterial hypertension

Johns Hopkins Medicine researchers report that rising blood levels of a protein called hematoma derived growth factor (HDGF) are linked to the increasing severity of pulmonary arterial hypertension, a form of damaging high blood pressure in the lungs.

20 Jun 2016

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Measuring antibody levels in the blood could be used to detect a person's heart attack risk after researchers, part-funded by the British Heart Foundation, discovered that higher levels of these antibodies are linked to a lower heart attack risk.

20 Jun 2016

Heart Failure News and Research

Further Reading

Breakthrough research could lead to new drugs to improve heart attack outcomes

Excessive weight at young age increases risk of heart failure

MOOD-HF supports lack of antidepressant efficacy in HF patients

New electric mesh device wraps around the heart to deliver electrical impulses

Pioglitazone effective in diabetes patients with NASH

Elevated troponin I should not rule out donor hearts

Jefferson researchers discover alternate pathway that helps heart keep pumping

Study highlights need to improve end-of-life care for all patients with serious illnesses

Re-engineering cardiac scarring process could improve clinical outcomes for heart disease patients

Race impacts adverse outcomes in atrial fibrillation

NCX1 protein could help prevent progression of heart failure

Could artificial intelligence help to combat stress? An interview with Davide Morelli

Study finds ARNI therapy could potentially prevent 28,484 deaths from heart failure each year

Protein-based CHD risk score developed

New protein risk score may help predict cardiovascular risk in patients with CHD

Researchers identify new myosin kinase that could optimize heart contractions

Fixed-dose combination of sacubitril and valsartan for heart failure shows differing added benefit

AF patients at risk for stroke mostly treated with aspirin-only prescription instead of blood thinners

New blood test could help predict severity of pulmonary arterial hypertension

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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