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Hematopoietic stem cell transplantation does not provide improvement for patients with Crohn disease

Among adults with difficult to treat Crohn disease not amenable to surgery, hematopoietic stem cell transplantation, compared with conventional therapy, did not result in significant improvement in sustained disease remission at l year and was associated with significant toxicity, according to a study in the December 15 issue of JAMA.

16 Dec 2015

Simple diagnostic test can help fight deadly sleeping sickness

Scientists have developed a quick and simple diagnosis method, similar to a dipstick pregnancy test, to fight a deadly sleeping sickness.

16 Dec 2015

Researchers test new concept in type 2 diabetes patients going into remission

Remission is well-known as the goal in cancer treatment but scientists are discovering it's also an exciting possibility for those with type 2 diabetes.

16 Dec 2015

NIDEK introduces AngioScan OCT Angiography for use with RS-3000 Advance OCT

NIDEK CO., LTD., a global leader in the design, manufacture, and distribution of ophthalmic, optometric, and lens edging equipment, is pleased to announce the launch of AngioScan OCT Angiography that enables visualization of retinal and choroidal microvasculature and blood flow with the RS-3000 Advance OCT.

16 Dec 2015

Study: Preoperative use of blood-thinning drugs associated with decreased risk of blood clots

Among patients undergoing major cancer operations, the preoperative use of blood-thinning drugs such as heparin does not increase rates of major bleeding or transfusions, and is associated with a decreased risk of blood clots, according to new study results published online in the Journal of the American College of Surgeons ahead of print publication early next year.

16 Dec 2015

BUSM researchers explore how do not resuscitate orders affect hospital rankings for pneumonia

Researchers from Boston University School of Medicine examined how hospital differences in patient preferences for life-sustaining treatments (do not resuscitate, or DNR, orders) affected hospital rankings for pneumonia.

16 Dec 2015

Molecular signatures can predict flu vaccine responses in young and old

What factors inhibit strong responses to seasonal flu vaccines in the elderly? Why do anti-flu antibodies last longer after vaccination in some people? Answers are emerging from an Emory University-based systems biology analysis of blood samples from more than 400 volunteers who received seasonal flu vaccines. Bali Pulendran, PhD, led a team of researchers who tracked patterns of gene expression, known as molecular signatures, of strong immune responses in volunteers' blood across five consecutive seasons from 2007 to 2011.

16 Dec 2015

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin.

16 Dec 2015

U of T researchers find another clue in understanding the cause of MS

Researchers at the University of Toronto have found another clue in understanding the cause of what drives Multiple Sclerosis (MS) disease. Their findings were published today in Immunity.

16 Dec 2015

Four UC Santa Barbara engineers named 2015 NAI fellows

Four UC Santa Barbara engineers have been elected to the National Academy of Inventors for 2015. Recognized for their "highly prolific spirit of invention," professors John Bowers, Craig Hawker, Umesh Mishra and Galen Stucky are among the newest fellows elected by the organization.

16 Dec 2015

Bridion injection approved to reverse effects of neuromuscular blocking drugs used during certain types of surgery

The U.S. Food and Drug Administration today approved Bridion (sugammadex) injection to reverse the effects of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide, which are used during certain types of surgery in adults.

16 Dec 2015

Kitov Pharmaceuticals' KIT-302 drug candidate meets primary efficacy endpoint in Phase III clinical trial

Kitov Pharmaceuticals, an innovative biopharmaceutical company focused on late-stage drug development, announced today that the Phase III, double-blind, placebo-controlled clinical trial for its leading drug candidate, KIT-302, successfully met the primary efficacy endpoint of the trial protocol as approved by the U.S. Food & Drug Administration (FDA).

15 Dec 2015

CytoSorbents partners with Hoang Long Pharma to bring CytoSorb to Vietnam

CytoSorbents Corporation, a leader in critical care immunotherapy commercializing its CytoSorb extracorporeal cytokine adsorber to control deadly inflammation using blood purification, today announced an exclusive multi-year distribution agreement with Hoang Long Pharma, a medical distributor in Vietnam specializing in the distribution of innovative pharmaceuticals, biologics, and devices to treat patients suffering from critical illnesses, immunologic disorders and deficiencies, and infections.

15 Dec 2015

Gene variant linked to psychotic symptoms, cognitive impairment in people with bipolar disorder identified

Researchers at Karolinska Institutet, and the Sahlgrenska Academy at Gothenburg University in Sweden have identified a gene variant linked to psychotic symptoms and cognitive impairment in people with bipolar disorder. The study, which is published in the journal Molecular Psychiatry, describes a possible mechanism for how the gene variant produces clinical symptoms by affecting levels of specific proteins in the brain.

15 Dec 2015

Researchers discover novel way to enhance, restore cancer suppressor activity in B-ALL

Researchers at Penn State College of Medicine, working with Chinese and American colleagues, have discovered a novel way to enhance and restore cancer suppressor activity in B-cell acute lymphoblastic leukemia, resulting in better outcomes in a pre-clinical model of the disease. The finding could pave the way for a new class of drugs for this and other forms of leukemia.

15 Dec 2015

Liver protein aids in accelerating growth of insulin-producing pancreatic 'beta' cells

More than a quarter of the 30 million people with diabetes in the United States depend on daily injections of insulin to maintain their blood glucose levels in a healthy range. Scientists are investigating many techniques to help treat or potentially even cure many of these patients by increasing the body's own insulin-producing pancreatic "beta" cells.

15 Dec 2015

Experimental drugs that modify cell metabolism also halt tumor growth

Experimental drugs that alter cell metabolism also halted tumor growth and extended survival in mice with cancers linked to changes in the same gene, according to a new study led by researchers at NYU Langone Medical Center, its Laura and Isaac Perlmutter Cancer Center and Massachusetts General Hospital.

15 Dec 2015

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

Researchers from the University of Arkansas for Medical Sciences and other institutions are reporting the discovery of the first broad spectrum drug that can potently kill senescent (or aging) cells in culture and effectively clear the cells in animals by specifically targeting a pathway that is critical for the survival of senescent cells.

15 Dec 2015

CAP2 gene responsible for cardiac conduction disease in mice

The presence or absence of the CAP2 gene causes sudden cardiac death in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania. In particular, the absence of the gene interrupts the animal's ability to send electrical signals to the heart to tell it to contract, a condition called cardiac conduction disease.

15 Dec 2015

New study reveals link between tinnitus severity and emotion processing in the brain

Tinnitus, otherwise known as ringing in the ears, affects nearly one-third of adults over age 65. The condition can develop as part of age-related hearing loss or from a traumatic injury. In either case, the resulting persistent noise causes varying amounts of disruption to everyday life.

15 Dec 2015

Blood News and Research

Hematopoietic stem cell transplantation does not provide improvement for patients with Crohn disease

Simple diagnostic test can help fight deadly sleeping sickness

Researchers test new concept in type 2 diabetes patients going into remission

NIDEK introduces AngioScan OCT Angiography for use with RS-3000 Advance OCT

Study: Preoperative use of blood-thinning drugs associated with decreased risk of blood clots

BUSM researchers explore how do not resuscitate orders affect hospital rankings for pneumonia

Molecular signatures can predict flu vaccine responses in young and old

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

U of T researchers find another clue in understanding the cause of MS

Four UC Santa Barbara engineers named 2015 NAI fellows

Bridion injection approved to reverse effects of neuromuscular blocking drugs used during certain types of surgery

Kitov Pharmaceuticals' KIT-302 drug candidate meets primary efficacy endpoint in Phase III clinical trial

CytoSorbents partners with Hoang Long Pharma to bring CytoSorb to Vietnam

Gene variant linked to psychotic symptoms, cognitive impairment in people with bipolar disorder identified

Researchers discover novel way to enhance, restore cancer suppressor activity in B-ALL

Liver protein aids in accelerating growth of insulin-producing pancreatic 'beta' cells

Experimental drugs that modify cell metabolism also halt tumor growth

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

CAP2 gene responsible for cardiac conduction disease in mice

New study reveals link between tinnitus severity and emotion processing in the brain

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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