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Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Findings of a new study led by Prof. XU Guowang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences and Prof. YANG Chunzhang from the National Cancer Institute shed light on the selective therapeutics for IDH1-mutated glioma by targeting glutathione synthesis pathway.

13 Apr 2020

Super-charging production of drugs for COVID-19

Researchers are ramping up production of a promising drug that has proven effective in obliterating SARS-CoV in cellular cultures. The team hopes that the drug might also be effective in the fight against SARS's close genetic cousin, the novel coronavirus (COVID-19).

13 Apr 2020

Why do so many pregnancies and in vitro fertilization attempts fail?

Scientists have created a mathematical model that can help explain why pregnancies and in vitro fertilization attempts fail.

13 Apr 2020

Remdesivir shows promise in post-infection treatment for COVID-19 disease

The coronavirus disease (COVID-19) has no approved treatment or vaccine as the world grapple with its wrath. The viral infection has so far infected 1.8 million and killed more than 114,000 people. Now, a team of scientists has shown that an experimental antiviral drug, remdesivir, has shown promise in treating patients with severe COVID-19.

13 Apr 2020

Free program to reduce and replace animal tests in scientific research

From June 22 to 25, students and early-career scientists will gather virtually for a free program of lectures, laboratory tours, interactive sessions, e-poster presentations, and virtual engagement with speakers and attendees on innovative methods to reduce and replace animal tests in toxicology and biomedical science.

11 Apr 2020

GlobalData: Australia’s commitment to support clinical trial ecosystem will benefit medical device sector

Australia is dedicating more government funding towards the establishment of a vibrant clinical trial ecosystem in order to accelerate the design, development, verification and product launch processes of medical devices, says GlobalData, a leading data and analytics company.

9 Apr 2020

New anti-COVID-19 system could potentially fight other viruses

The ongoing COVID-19 pandemic has sparked many research projects to meet the challenge of the virus and come up with measures to fight its activity. A new study published in the journal Cell Host & Microbe in April 2020 describes a novel system to help scientists understand the virus, including mutations, diagnose infections, and also to develop and evaluate vaccines more quickly.

8 Apr 2020

Using ultrasensitive protein detection method to evaluate embryo quality

Infertility is estimated to affect 9% of reproductive-aged couples globally, and many couples consequently turn to assisted reproductive technology.

7 Apr 2020

Metrion Biosciences and International Scientific Consortium publish data and new recommendations for in vitro risk assessment of the cardiac safety of new medicines

Metrion today announced it has contributed to two new peer-reviewed papers under the U.S. FDA CiPA (Comprehensive in vitro Proarrhythmia Assay) initiative.

From Metrion Biosciences Limited 7 Apr 2020

New project aims to develop flexible, injectable microstimulators to restore movement in paralysis

The project Electronic AXONs: wireless microstimulators based on electronic rectification of epidermically applied currents (eAXON, 2017-2022), funded by a European Research Council (ERC) Consolidator Grant awarded to Antoni Ivorra, head of the Biomedical Electronics Research Group (BERG) of the Department of Information and Communication Technologies (DTIC) at UPF principally aims to "develop very thin, flexible, injectable microstimulators to restore movement in paralysis", says Ivorra, principal investigator of the project.

7 Apr 2020

Antiparasitic drug Ivermectin kills coronavirus in 48 hours

Around the world, scientists race to develop a vaccine or treatment against the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Now, a team of researchers has found that a drug already available around the world can kill the coronavirus in a lab setting in just 48 hours.

6 Apr 2020

Experimental drug APN01 prevents COVID-19 infection in the lab

With the world gripped with the COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is a frantic rush to find an effective drug that can be used to treat the disease.

6 Apr 2020

ATS releases new guidance to help clinicians manage COVID-19 patients

An American Thoracic Society-led international task force has released a guidance document to help clinicians manage COVID-19 patients in the face of a worldwide pandemic and minimal empirical evidence to guide treatment.

6 Apr 2020

UC San Diego Health expands COVID-19 testing capacity

From the beginning, the ability of front line clinicians to test patients for COVID-19 -- to determine whether a person is infected with the disease-causing novel coronavirus, SARS-CoV-2 -- has been part and parcel of the pandemic.

6 Apr 2020

Siemens Healthineers releases test kit for coronavirus COVID-19

Siemens Healthineers announced today the availability of its molecular Fast Track Diagnostics SARS-CoV-2 Assay test kit used to aid in the diagnosis of infection by the SARS-CoV-2 virus that causes the COVID-19 disease.

From Siemens Healthineers Point of Care Diagnostics 6 Apr 2020

Researchers find direct link between MCL1 protein and cell-cycle checkpoint protein

Human cells respond to stresses like DNA damage, metabolic imbalance and starvation by first trying to repair the problem.

5 Apr 2020

Scientists examine the molecular causes of rare hereditary disease

Scientists in EMBL Barcelona’s Ebisuya group, with collaborators from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, have studied oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro, to explore the molecular causes of a rare human hereditary disease known as spondylocostal dysostosis.

5 Apr 2020

Australian scientists identify possible coronavirus drug

A collaborative study led by Monash University's Biomedicine Discovery Institute in Melbourne, Australia, with the Peter Doherty Institute of Infection and Immunity, has shown that an anti-parasitic drug already available around the world kills the virus within 48 hours.

3 Apr 2020

GlobalData: Rapid POC tests to accelerate testing capacity for diagnosing COVID-19

There is a current worldwide lack of testing capacity for the novel coronavirus (COVID-19) outbreak. The frontline response for diagnosing COVID-19 has been polymerase chain reaction (PCR) testing.

3 Apr 2020

Excess cardiac myosin worsens damage to heart tissue during a heart attack

A prevalent heart protein known as cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot--worsening damage to heart tissue, a new study shows.

2 Apr 2020