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New class of diabetes drugs differs in efficacy and safety profiles, shows new research

Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) differ in their efficacy and safety profiles, according to new research by the University of Leicester.

10 Dec 2015

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

Pulmonary hypertension is an umbrella term used for many conditions that all result in elevation of the pulmonary arterial pressure. Of interest, many of these completely different clinical and pathophysiological entities result in a final common pathway of vasoconstriction, micro thrombosis and vascular remodelling.

10 Dec 2015

New study may help doctors to better treat children who cope with chronic pain

A new study describes the development of pediatric pain measures for a National Institutes of Health Initiative aimed at helping doctors better evaluate and therefore better treat children who cope with chronic pain. Based on face-to-face interviews with pediatric patients, the study better captured the young patient's perspective of living with chronic pain.

9 Dec 2015

TET proteins needed to maintain genome instability, say researchers

Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, but how they keep a lid on the uncontrolled cell proliferation of cancer cells had remained uncertain. Now, researchers at the La Jolla Institute for Allergy and Immunology demonstrate that TET proteins collectively constitute a major class of tumor suppressors and are required to maintain genome instability.

9 Dec 2015

New study shows wide disparities in access to minimally invasive hysterectomies for uterine cancer

A new study led by Johns Hopkins researchers shows wide racial and economic disparities in access to minimally invasive hysterectomies for early uterine cancer in the United States. This is despite years of accumulating evidence that the procedures to remove the uterus are linked to fewer postoperative complications, the researchers say.

9 Dec 2015

Study finds link between congenital heart disease and neurodevelopmental disorders

Researchers from Columbia University Medical Center, NewYork-Presbyterian, the Pediatric Cardiac Genetics Consortium, and the Pediatric Heart Network have found a number of genetic mutations that explain why many children with congenital heart disease also have other significant health challenges, including neurodevelopmental disorders and other congenital problems.

9 Dec 2015

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

Considerable racial disparities exist in surgical outcomes for black and Hispanic patients undergoing major cancer and non-cancer surgeries in U.S. hospitals, even among institutions that have already enrolled in a national surgical quality improvement initiative.

9 Dec 2015

UT awarded $1 million USDA grant to combat childhood obesity

One of every three children in Tennessee is overweight, and more than 20 percent of our children are obese. Childhood obesity has been linked to diabetes, high blood pressure, depression and poor academic performance.

9 Dec 2015

New portable sensor can measure vitamin C levels in fluids that leak from the eye

An engineer and an ophthalmologist are developing a portable sensor that can quickly and inexpensively determine whether an eye injury is mild or severe. The device, called OcuCheck, measures levels of vitamin C in the fluids that coat or leak from the eye.

9 Dec 2015

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

Some of the same gene mutations that cause heart defects in children also lead to neurodevelopmental delays, including learning disabilities. A large study of congenital heart disease (CHD) reveals overlapping genetic influences during early childhood development.

9 Dec 2015

Research examines ketone esters to combat hyperbaric oxygen toxicity in Navy divers

For the first time, ketone esters-oral supplements useful in epilepsy treatment-are being studied to fight seizures caused by hyperbaric oxygen toxicity, a life-threatening byproduct of breathing too much oxygen that impacts deep-water divers.

9 Dec 2015

Flagship launches Rubius to develop functionalized red blood cells for treatment of serious diseases

Flagship Ventures, a leading innovation and venture firm focused on healthcare and sustainability, announced it has launched Rubius Therapeutics, to develop functionalized red blood cells for the treatment of autoimmune conditions, metabolic diseases, cancer, and other serious diseases.

9 Dec 2015

FDA clears for marketing first cooling cap to reduce chemotherapy-induced hair loss

Today, the U.S. Food and Drug Administration cleared for marketing in the United States the first cooling cap to reduce hair loss (alopecia) in female breast cancer patients undergoing chemotherapy.

9 Dec 2015

Gene may play role in protecting breast cancer patients from developing chemobrain

A team of researchers from the National University of Singapore has established that variation of a gene may have a role in protecting cancer patients from developing chemotherapy-induced cognitive impairment, commonly known as 'chemofog' or 'chemobrain'.

9 Dec 2015

New article reveals link between poor kidney function, worse outcomes after heart surgery

Poor kidney function prior to heart surgery can lead to worse outcomes, higher surgical costs, and a longer hospital stay, according to an article posted online today by The Annals of Thoracic Surgery.

9 Dec 2015

Arterial grafts provide better outcomes than venous grafts in heart bypass surgery patients

The Society of Thoracic Surgeons has released new clinical practice guidelines that recommend expanding the use of arteries from the chest and forearm rather than using veins from the leg when performing coronary artery bypass grafting (CABG) surgery in certain patients. The guidelines, posted online today, will appear in the February 2016 issue of The Annals of Thoracic Surgery.

9 Dec 2015

Palbociclib and paclitaxel combination shrinks tumors in patient with ER positive breast cancer

Combining the new breast cancer drug palbociclib with paclitaxel (Taxol) shrank tumors in nearly half of patient with estrogen-receptor (ER) positive breast cancer, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

9 Dec 2015

UC San Diego researchers awarded MJFF grant to identify biomarkers for Parkinson's disease

Parkinson's disease is difficult to diagnose, particularly in its early stages. Now, researchers at University of California, San Diego School of Medicine - aided by a $375,000 grant from The Michael J. Fox Foundation for Parkinson's Research - hope to improve the prospects of early diagnosis by identifying a biological signpost in the blood.

9 Dec 2015

UGA researchers identify biological markers for mental disorders

A team of researchers led by faculty at the University of Georgia has identified a number of biological markers that make it possible to classify mental disorders with greater precision. Their findings, published today in the American Journal of Psychiatry, may one day lead to improved diagnostics and treatments for those suffering from mental illness.

9 Dec 2015

Mayo Clinic investigators discover potential diagnostic markers for bipolar I disorder

Mayo Clinic researchers have discovered a series of proteins that could be diagnostic markers to identify bipolar I disorder. If this discovery sample can be validated through replication these markers may help as a diagnostic tool for psychiatrists treating mood disorders.

9 Dec 2015

Blood News and Research

New class of diabetes drugs differs in efficacy and safety profiles, shows new research

Study reveals pathogenetic role of miR-125a in pulmonary hypertension

New study may help doctors to better treat children who cope with chronic pain

TET proteins needed to maintain genome instability, say researchers

New study shows wide disparities in access to minimally invasive hysterectomies for uterine cancer

Study finds link between congenital heart disease and neurodevelopmental disorders

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

UT awarded $1 million USDA grant to combat childhood obesity

New portable sensor can measure vitamin C levels in fluids that leak from the eye

Gene mutations that cause congenital heart disease also lead to neurodevelopmental delays

Research examines ketone esters to combat hyperbaric oxygen toxicity in Navy divers

Flagship launches Rubius to develop functionalized red blood cells for treatment of serious diseases

FDA clears for marketing first cooling cap to reduce chemotherapy-induced hair loss

Gene may play role in protecting breast cancer patients from developing chemobrain

New article reveals link between poor kidney function, worse outcomes after heart surgery

Arterial grafts provide better outcomes than venous grafts in heart bypass surgery patients

Palbociclib and paclitaxel combination shrinks tumors in patient with ER positive breast cancer

UC San Diego researchers awarded MJFF grant to identify biomarkers for Parkinson's disease

UGA researchers identify biological markers for mental disorders

Mayo Clinic investigators discover potential diagnostic markers for bipolar I disorder

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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