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New approach helps Group Health to increase rates of lifesaving screening for colon cancer

Mailing yearly stool kits--an alternative to the often-dreaded colonoscopy--has helped Group Health to boost rates of lifesaving screening for colon cancer, according to new research from Group Health Research Institute.

17 Nov 2015

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells.

17 Nov 2015

CRI scientists identify emergency blood-formation system inside the body

Scientists at the Children's Medical Center Research Institute at UT Southwestern have determined how the body responds during times of emergency when it needs more blood cells. In a study published in Nature, researchers report that when tissue damage occurs, in times of excessive bleeding, or during pregnancy, a secondary, emergency blood-formation system is activated in the spleen.

17 Nov 2015

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

University of Cincinnati researchers have discovered the negative impact a high fat diet has on red blood cells and how these cells, in turn, promote the development of cardiovascular disease.

17 Nov 2015

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long-term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.

17 Nov 2015

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

Researchers at the University of Arizona have invented a device that for the first time allows neurosurgeons, who use microscopes extensively while operating, to see blood flowing inside vessels and more clearly distinguish cancerous from healthy tissue under the microscope.

17 Nov 2015

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted accelerated approval for Darzalex (daratumumab) to treat patients with multiple myeloma who have received at least three prior treatments. Darzalex is the first monoclonal antibody approved for treating multiple myeloma.

17 Nov 2015

Research collaboration aims to develop new drug for slow-healing chronic wounds

The biotech company Omnio based in Swedish Umeå, and led by researcher Tor Ny at Umeå University, launches a research collaboration with the Canadian pharmaceutical company ProMetic to develop a new drug for slow-healing chronic wounds. The collaboration includes funding for clinical studies of a drug based on the blood plasma protein plasminogen.

15 Nov 2015

Tyrogenex announces results from phase 1 study of orally-administered X-82 in patients with AMD

Tyrogenex, a privately held company focused on the development of targeted therapeutics for cancer and ophthalmology, today announced data from its phase 1 open-label study of orally-administered X-82 in patients for wet age-related macular degeneration (AMD).

15 Nov 2015

Ranibizumab may become reasonable treatment alternative for patients with proliferative diabetic retinopathy

Among patients with proliferative diabetic retinopathy, treatment with an injection in the eye of the drug ranibizumab resulted in visual acuity that was not worse than panretinal photocoagulation at 2 years, according to a study appearing in JAMA.

15 Nov 2015

UC Irvine Health researchers develop one-step test to detect HCV infections

UC Irvine Health researchers have developed a cost-effective one-step test that screens, detects and confirms hepatitis C virus (HCV) infections. Dr. Ke-Qin Hu, director of hepatology services, will present findings at the Annual Meeting of American Association for the Study of Liver Disease in San Francisco, Nov. 14-16. Current blood-based HCV testing requires two steps and can be expensive, inconvenient and is not widely available or affordable globally.

15 Nov 2015

Adynovate approved for patients with Hemophilia A

The U.S. Food and Drug Administration today approved Adynovate, Antihemophilic Factor (Recombinant), PEGylated for use in adults and adolescents, aged 12 years and older, who have Hemophilia A. Adynovate is modified to last longer in the blood and potentially require less frequent injections than unmodified Antihemophilic Factor when used to reduce the frequency of bleeding.

15 Nov 2015

First hospital installs Ortho Vision Analyzer

Ortho Clinical Diagnostics today announced that Terre Haute Regional Hospital is the first U.S. medical center to install the ORTHO VISIONTM Analyzer, a highly interactive, fully automated analyzer for transfusion medicine laboratories.

13 Nov 2015

Diabetes prevention begins in the womb

60 million people worldwide are living with diabetes mellitus, and one in ten people over the age of 25 will develop the condition (type 2) at some stage in their lives. Globally, around 3.4 million people die from diabetes and its consequences every year. "Every six seconds, somebody somewhere in the world dies from diabetes", says Alexandra Kautzky-Willer from the Department of Endocrinology and Metabolism at the MedUni Vienna's University Department of Internal Medicine III.

13 Nov 2015

New device can measure glucose in blood through urine

Two young technologists from the Technological Institute of Chihuahua, in the north of Mexico, developed a device that can measure glucose in blood through the urine on the toilet, it activates via smart phone bluetooth, daily recording the values.

13 Nov 2015

Houston Methodist investigator awarded NCI grant to study detection strategies for breast cancer-specific subtypes

The National Cancer Institute awarded Houston Methodist investigator Randa El-Zein, M.B., Ch.B., Ph.D., a $2.8 million, five-year U01 grant to combine mammography features with blood-based biomarkers to more precisely predict a woman's risk for breast cancer-specific subtypes.

13 Nov 2015

Blood News and Research

New approach helps Group Health to increase rates of lifesaving screening for colon cancer

Changes in cellular metabolites regulate earliest stages of embryonic stem cell development

CRI scientists identify emergency blood-formation system inside the body

Negative impact of high-fat diet on red blood cells may promote development of cardiovascular disease

Drug prevents onset of cognitive and cellular effects in mouse model of Alzheimer’s disease

Augmented microscopy may allow neurosurgeons to clearly distinguish cancerous from healthy tissue

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Research collaboration aims to develop new drug for slow-healing chronic wounds

Tyrogenex announces results from phase 1 study of orally-administered X-82 in patients with AMD

Ranibizumab may become reasonable treatment alternative for patients with proliferative diabetic retinopathy

UC Irvine Health researchers develop one-step test to detect HCV infections

Adynovate approved for patients with Hemophilia A

First hospital installs Ortho Vision Analyzer

Diabetes prevention begins in the womb

New device can measure glucose in blood through urine

Houston Methodist investigator awarded NCI grant to study detection strategies for breast cancer-specific subtypes

Research identifies liver pathway that contributes to negative effects of high-fat, high-cholesterol junk food diet

Cornell biomedical engineers develop 'super natural killer cells' to destroy cancer cells in lymph nodes

New study provides possible way to overcome stem cell research’s developmental arrest problem

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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