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CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets.

19 Jan 2017

Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Mutations in a gene that should enable memories and a sense of direction instead can result in imprecise communication between neurons that contributes to symptoms of schizophrenia, scientists report.

19 Jan 2017

Influenza experts examine evolution of avian disease

Few influenza viruses are as widespread and adaptable as avian influenza viruses, and scientists are not entirely sure why.

19 Jan 2017

RIT research explores impact of shear stress on cells moving through blood vessels

How do cells and protein molecules respond to stress as they travel through blood vessels? Could resulting changes to these biological components impact how diseases are spread?

19 Jan 2017

Scientists harness rabies viruses for assessing connectivity of nerve cell transplants

Scientists under the leadership of the University of Bonn have harnessed rabies viruses for assessing the connectivity of nerve cell transplants: coupled with a green fluorescent protein, the viruses show where replacement cells engrafted into mouse brains have connected to the host neural network.

19 Jan 2017

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Neurotransmitter transporters are some of the most popular transport proteins in research as they play a major role in the processing of signals in the brain. A joint study by TU Wien and the Medical University of Vienna has now successfully demonstrated for the first time the structural impact of membrane lipids on medically relevant serotonin transporters.

19 Jan 2017

Endogenous peptide inhibits atherosclerosis by reducing cholesterol levels

Cells of the innate immune system that play an important role in development of atherosclerosis contain a protein that reduces levels of cholesterol in mice - and thus helps to inhibit or mitigate the disease.

19 Jan 2017

New way of repurposing existing drugs could unearth promising treatments for Parkinson’s disease

By bringing together cutting-edge stem cell technologies and computational biology, researchers at Oxford University have developed a unique way to identify existing drugs that could potentially be repurposed for treating Parkinson’s.

19 Jan 2017

Researchers explore ins and outs of genome sequencing in newborns

When you have a baby, a nurse or a phlebotomist performs a heel stick to take a few drops of blood from your infant and sends it off to a state lab for a battery of tests.

19 Jan 2017

Overall survival of advanced NSCLC patients receiving treatment better than untreated patients

Non-small cell lung cancer patients with advanced disease receiving standard of care treatment have a higher overall survival than similar patients not receiving treatment.

19 Jan 2017

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression.

19 Jan 2017

‘Collateral lethality’ may create new therapeutic options for several cancers

Cancer cells often delete genes that normally suppress tumor formation. These deletions also may extend to neighboring genes, an event known as "collateral lethality," which may create new options for development of therapies for several cancers.

19 Jan 2017

Study identifies molecular signals that maintain nerve cell structures in the adult brain

Humans and other vertebrates depend on a portion of the brain called the hippocampus for learning, memory and their sense of location. Nerve cell structures in the adult hippocampus are sustained by factors whose identities have remained largely mysterious so far.

19 Jan 2017

Researchers uncover new pathway in the body that stimulates liver repair

A team of Michigan State University researchers, led by James Luyendyk in the College of Veterinary Medicine, has uncovered a new pathway in the body that stimulates liver repair.

19 Jan 2017

Research finding provides new target for regulating cell division

Modern genome sequencing methods used to measure the efficiency of synthesis of individual protein during cell division has found that the enzymes that make lipids and membranes were synthesized at much greater efficiency when a cell is ready to split.

19 Jan 2017

Researchers show how adult learning is impaired in females using mouse models of Rett syndrome

Neurodevelopmental disorders like autism very likely have their origin at the dawn of life, with the emergence of inappropriate connectivity between nerve cells in the brain.

19 Jan 2017

Sedentary lifestyle may hasten biological aging

Researchers at University of California San Diego School of Medicine report that elderly women who sit for more than 10 hours a day with low physical activity have cells that are biologically older by eight years compared to women who are less sedentary.

18 Jan 2017

Cell News and Research

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Influenza experts examine evolution of avian disease

RIT research explores impact of shear stress on cells moving through blood vessels

Scientists harness rabies viruses for assessing connectivity of nerve cell transplants

Study shows structural impact of membrane lipids on medically relevant serotonin transporters

Endogenous peptide inhibits atherosclerosis by reducing cholesterol levels

New way of repurposing existing drugs could unearth promising treatments for Parkinson’s disease

Researchers explore ins and outs of genome sequencing in newborns

Overall survival of advanced NSCLC patients receiving treatment better than untreated patients

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

‘Collateral lethality’ may create new therapeutic options for several cancers

Study identifies molecular signals that maintain nerve cell structures in the adult brain

Researchers uncover new pathway in the body that stimulates liver repair

Research finding provides new target for regulating cell division

Researchers show how adult learning is impaired in females using mouse models of Rett syndrome

Sedentary lifestyle may hasten biological aging

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

Stem cell research offers alternative view of cancer metastasis

Scientists discover new molecular information on how the brain regulates depression and anxiety

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