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New triplet therapies show promise for relapsed and newly diagnosed leukemias

Three clinical trials led by researchers from The University of Texas MD Anderson Cancer Center demonstrated significant positive results from novel triplet therapies in the treatment of relapsed or refractory and newly diagnosed leukemias.

9 Dec 2024

How lifestyle and health shape your dementia risk

New RAND research identifies early predictors of cognitive impairment and dementia using a nationally representative U.S. dataset, highlighting the role of modifiable factors and baseline cognitive health in prevention and intervention strategies.

9 Dec 2024

Novel drug combination shows promise for CLL treatment

A novel, fixed-duration drug combination - consisting of a second-generation BTK inhibitor, called acalabrutinib, plus a BCL-2 inhibitor (venetoclax), with or without a third blood cancer drug - shows deep and durable responses in patients with chronic lymphocytic leukemia (CLL), Dana-Farber Cancer Institute investigator Jennifer Brown, MD, PhD, reports at the 66th American Society for Hematology (ASH) Annual Meeting and Exposition, on behalf of the trial investigators.

9 Dec 2024

Post-COVID health risks: Obesity fuels sequelae, smoking hits memory

Obesity significantly increases the risk of post-COVID-19 long-term sequelae, while smoking is primarily linked to memory disorders but does not raise the risk of long COVID symptoms or hospitalization.

9 Dec 2024

Unprocessed red meat and weight loss: Is it a healthy choice?

Unprocessed red meat can be part of a healthy weight maintenance diet after rapid weight loss, with no adverse effects on metabolism or cardiovascular health. This study finds similar outcomes with diets including 25g or 150g of red meat daily.

9 Dec 2024

New guidelines developed for the diagnosis and management of premature ovarian insufficiency

New guidelines on the diagnosis and management of premature ovarian insufficiency (POI) – developed by the Centre for Research Excellence in Women's Health in Reproductive Life (CRE-WHiRL) at Monash University, and key international women's health organizations with an international team of experts including women with lived experience – will be published today (TBC) simultaneously in three leading journals.

9 Dec 2024

Healthy diet can help reduce the severity of chronic pain

Chronic pain is an acute and debilitating condition that affects millions of people worldwide. And while pain interventions are available, many people struggle without treatment at all.

9 Dec 2024

New brain stimulation trial aims to improve cognitive recovery from TBI

Traumatic brain injury (TBI) is a leading cause of death and disability among young people in the United States and is the most devastating survivable injury in modern warfare, according to the University of Cincinnati's Ishita Basu.

9 Dec 2024

MRI study offers new insights into celiac disease treatment

Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with coeliac disease, which could be the first step towards finding new ways of treating the condition.

6 Dec 2024

Researchers discover new receptor in pain signaling pathway

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a study published in the Journal of Clinical Investigation.

6 Dec 2024

New collaborative effort aims to cure ALK-positive lung cancer

Lung cancer is the leading cause of cancer death worldwide, with various subtypes affecting millions of people each year.

6 Dec 2024

Antidepressant use linked to persistent genital sensitivity loss

The use of antidepressants is associated with sexual side effects including reduced genital sensitivity that persists after stopping the medication, a new Simon Fraser University study finds.

6 Dec 2024

Chronic traumatic encephalopathy risk in ice hockey increases with each year played

A study of 77 male hockey players reveals a 96.4% CTE prevalence, highlighting the link between play duration and increased risk of chronic encephalopathy.

6 Dec 2024

A reduction in BMI among adults is associated with lower health care spending, study suggests

A study reveals that weight loss can lead to significant healthcare savings, with 7% savings for a 5% BMI reduction and 30% for a 25% reduction in adults.

6 Dec 2024

How measles, whooping cough, and worse could roar back on RFK Jr.’s watch

The availability of safe, effective covid vaccines less than a year into the pandemic marked a high point in the 300-year history of vaccination, seemingly heralding an age of protection against infectious diseases.

6 Dec 2024

New computational pipeline identifies key biomarkers for Alzheimer's disease

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD).

6 Dec 2024

Dupilumab improves symptoms of atopic dermatitis in children with co-existing conditions

Research at National Jewish Health and other institutions has shown that the biologic dupilumab improves signs and symptoms of moderate-to-severe atopic dermatitis (eczema) in young children whether or not they have another inflammatory condition, such as asthma, allergic rhinitis or food allergies.

5 Dec 2024