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Children living in non-redeveloped public housing more likely to take repeated trips to emergency rooms

San Francisco children living in non-redeveloped public housing are 39 percent more likely to repeatedly visit emergency rooms, according to new research from UC San Francisco and UC Berkeley.

9 Dec 2014

Better planning needed to improve mother-infant outcomes in hospitals, say CHOP researchers

What does it mean for expectant mothers and hospitals when there are large-scale closures of maternity units? A new study led by researchers at The Children's Hospital of Philadelphia provides an inside view from hospital staff members in Philadelphia, where 13 out of 19 obstetric units closed in a 15-year period.

9 Dec 2014

Simple rectal swab cultures can thwart drug-resistant E. coli in patients undergoing TRUSBx procedures

Some infections after prostate biopsy due to drug-resistant Escherichia coli can be thwarted by simple rectal swab cultures prior to the procedure. The cultures test for antibiotic-resistant E. coli, and the findings are used to direct the selection of antimicrobial prophylaxis used for the procedure, according to Rhode Island Hospital researchers.

9 Dec 2014

Study: Injectable 3D vaccines could help prevent cancer, infectious disease

One of the reasons cancer is so deadly is that it can evade attack from the body's immune system, which allows tumors to flourish and spread. Scientists can try to induce the immune system, known as immunotherapy, to go into attack mode to fight cancer and to build long lasting immune resistance to cancer cells.

9 Dec 2014

Nationwide Children's Hospital receives ANCC Magnet Recognition for third time

The American Nurses Credentialing Center's Magnet Recognition Program for excellence in nursing services has granted Nationwide Children's Hospital ANCC Magnet Recognition for a third time. This prestigious recognition is the ultimate benchmark in nursing excellence and is awarded to only about seven percent of the nation's more than 6,000 hospitals across the country.

8 Dec 2014

PRM-151 compound shows positive results for treating advanced myelofibrosis

A study that investigated the potential of the compound PRM-151 (PRM) for reducing progressive bone marrow fibrosis (scarring) in patients with advanced myelofibrosis has shown initial positive results. Myelofibrosis is a life-threatening bone marrow cancer.

8 Dec 2014

Findings open new avenues for research to predict risk of therapy-related AML

For a small percentage of cancer patients, treatment aimed at curing the disease leads to a form of leukemia with a poor prognosis. Conventional thinking goes that chemotherapy and radiation therapy induce a barrage of damaging genetic mutations that kill cancer cells yet inadvertently spur the development of acute myeloid leukemia (AML), a blood cancer.

8 Dec 2014

Spark Therapeutics, Pfizer partner to develop SPK-FIX for potential treatment of hemophilia B

Spark Therapeutics, a late-stage gene therapy company developing treatments for debilitating genetic diseases, announced today that it has entered into a global collaboration with Pfizer Inc. for the development and potential commercialization of SPK-FIX, a development program advancing proprietary, bio-engineered adeno-associated virus (AAV) vectors for the potential treatment of hemophilia B.

8 Dec 2014

Henry Ford Hospital recruits patients to participate in brain cancer clinical trial

Henry Ford Hospital today announced that it is actively recruiting patients to participate in a clinical trial taking place at the Hermelin Brain Tumor Center which is showing promising results in patients with brain cancer.

8 Dec 2014

New kind of knee surgery provides much needed relief for patients

A new kind of knee surgery is providing much needed relief for patients in the greater Houston area. For many years, anterior cruciate ligament (ACL) reconstructions have been frequently performed to correct instability in the knee, however many patients never return to their pre-injury level of activity following surgery. That is changing, says orthopaedic surgeon Dr. William Hayes, because surgeons are now addressing injuries to the anterolateral ligament (ALL) in the knee as well.

8 Dec 2014

New fluorescence-imaging agent could improve diagnosis, guide surgeons during tumor removal

CEA-Leti and CLARA today announced the development of a new fluorescence-imaging agent that could significantly increase surgeons’ accuracy when removing cancerous tumors.

8 Dec 2014

Children born prematurely need to be placed in a priority group for seasonal flu vaccination

Children born prematurely are at an increased risk of flu-related complications, despite not being identified as an “at risk” group in UK, USA, or WHO guidelines, and should be a priority group for the seasonal flu vaccination, new research published in The Lancet Respiratory Medicine suggests.

8 Dec 2014

Researchers report promising outcomes from clinical trial in patients with dyskeratosis congenita

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only. This is the first trial reporting successful transplant in dyskeratosis congenita (DC) patients without the use of any radiation or conventional cytotoxic chemotherapy beforehand.

8 Dec 2014

Weight-loss surgery may reduce lower urinary tract symptoms

Metabolic syndrome is linked with an increased frequency and severity of lower urinary tract symptoms, but weight loss surgery may lessen these symptoms. The findings, which come from two studies published in BJU International, indicate that urinary problems may be added to the list of issues that can improve with efforts that address altered metabolism.

8 Dec 2014

Subsets of cells drive spread of multiple myeloma

Although it is among the most highly metastatic of all cancers, multiple myeloma is driven to spread by only a subset of the myeloma cells within a patient's body, researchers at Dana-Farber Cancer Institute have found in a study presented at the annual meeting of the American Society of Hematology.

8 Dec 2014

Baylor-led researchers identify gene linked to familial glioma

An international consortium of researchers led by Baylor College of Medicine has identified for the first time a gene associated with familial glioma (brain tumors that appear in two or more members of the same family) providing new support that certain people may be genetically predisposed to the disease.

8 Dec 2014

Novel targeted therapies and treatment combinations for leukemia

Recognizing that leukemia cannot be conquered with a "one-size-fits-all" approach, researchers are pursuing novel targeted therapies and combinations of existing treatment regimens with new agents for patient populations with historically poor prognoses, according to data presented today during the 56th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2014

Breakthrough therapy shows promise in resistant forms of Hodgkin lymphoma

A therapy that liberates the immune system to attack cancer cells drove Hodgkin lymphoma (HL) into complete or partial remission in fully 87 percent of patients with resistant forms of the disease who participated in an early-phase clinical trial, investigators at Dana-Farber Cancer Institute and partnering institutions report in a study published today in the New England Journal of Medicine and simultaneously presented at the annual meeting of the American Society of Hematology in San Francisco.

7 Dec 2014

Emerging strategies to boost healthy RBCs may reduce burden of anemia linked to blood disorders

Emerging treatment approaches may reduce the burden of anemia associated with blood disorders by enhancing production of healthy red blood cells, according to data presented today at the 56th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2014

Nivolumab drug highly effective for Hodgkin's lymphoma

A phase I clinical trial of nivolumab found that the immune-boosting drug is a highly effective therapy for Hodgkin's lymphoma. The multi-institution study, led by Mayo Clinic, indicated that the drug was safe and led to an 87 percent response rate in patients who had failed on other treatments.

7 Dec 2014

Hospital News and Research

Children living in non-redeveloped public housing more likely to take repeated trips to emergency rooms

Better planning needed to improve mother-infant outcomes in hospitals, say CHOP researchers

Simple rectal swab cultures can thwart drug-resistant E. coli in patients undergoing TRUSBx procedures

Study: Injectable 3D vaccines could help prevent cancer, infectious disease

Nationwide Children's Hospital receives ANCC Magnet Recognition for third time

PRM-151 compound shows positive results for treating advanced myelofibrosis

Findings open new avenues for research to predict risk of therapy-related AML

Spark Therapeutics, Pfizer partner to develop SPK-FIX for potential treatment of hemophilia B

Henry Ford Hospital recruits patients to participate in brain cancer clinical trial

New kind of knee surgery provides much needed relief for patients

New fluorescence-imaging agent could improve diagnosis, guide surgeons during tumor removal

Children born prematurely need to be placed in a priority group for seasonal flu vaccination

Researchers report promising outcomes from clinical trial in patients with dyskeratosis congenita

Weight-loss surgery may reduce lower urinary tract symptoms

Subsets of cells drive spread of multiple myeloma

Baylor-led researchers identify gene linked to familial glioma

Novel targeted therapies and treatment combinations for leukemia

Breakthrough therapy shows promise in resistant forms of Hodgkin lymphoma

Emerging strategies to boost healthy RBCs may reduce burden of anemia linked to blood disorders

Nivolumab drug highly effective for Hodgkin's lymphoma

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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