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People with first-episode psychosis may benefit from medication treatment changes, study finds

Many patients with first-episode psychosis receive medications that do not comply with recommended guidelines for first-episode treatment, researchers have found. Current guidelines emphasize low doses of antipsychotic drugs and strategies for minimizing the side effects that might contribute to patients stopping their medication.

5 Dec 2014

Study: PET scanning strategy could help predict effectiveness of TB drugs

Sophisticated lung imaging can show whether or not a treatment drug is able to clear tuberculosis (TB) lung infection in human and macaque studies, according to researchers at the University of Pittsburgh School of Medicine and their international collaborators.

5 Dec 2014

Study on hospital alarm fatigue records more than 2.5 million alarms in one month

Jessica Zègre-Hemsey, a cardiac monitoring expert at the University of North Carolina at Chapel Hill, and her colleagues at the University of California San Francisco, revealed more than 2.5 million alarms were triggered on bedside monitors in a single month - the first figure ever reported from a real-world hospital setting.

5 Dec 2014

New single-cell genetic profiling techniques help uncover variation in pluripotent stem cells

Stem cells offer great potential in biomedical engineering due to their pluripotency, which is the ability to multiply indefinitely and also to differentiate and develop into any kind of the hundreds of different cells and bodily tissues. But the precise complexity of how stem cell development is regulated throughout states of cellular change has been difficult to pinpoint until now.

5 Dec 2014

DePuy Synthes Spine receives FDA clearance to market VEPTR/VETPR II Devices for TIS treatment

DePuy Synthes Spine today announced it has received 510(k) clearance from the U.S. Food and Drug Administration to market the VEPTR/VEPTR II Vertical Expandable Prosthetic Titanium Rib Devices for the treatment of Thoracic Insufficiency Syndrome (TIS), a rare congenital condition where severe deformities of the chest, spine or ribs impair breathing and lung growth in children.

5 Dec 2014

SurgiQuest receives Most Promising Life Sciences Company of the Year award

SurgiQuest was awarded "Most Promising Life Sciences Company of the Year" due to its potential for growth, success and impact on the Life Sciences market in Connecticut. The company's flagship product, the AirSeal System, improves patient outcomes, enhances perioperative efficiency, reduces costs and increases hospital profitability.

4 Dec 2014

Disease-associated malnutrition imposes economic burden on society

Even in food-abundant industrialized countries like the U.S., an alarming number of people, particularly seniors, are in a state of diseased-associated malnutrition. Because of the impact on patient health, disease-associated malnutrition imposes a significant economic burden on society of $157 billion per year, according to new research published in a supplemental issue of the Journal of Parenteral and Enteral Nutrition and supported by Abbott.

4 Dec 2014

Fiagon's ENT Extended Instrument Set receives FDA approval

Fiagon AG medical technologies announced today that it received U.S. Food and Drug Administration 510(k) clearance for its ear, nose and throat (ENT) Extended Instrument Set. The clearance includes the company's tip-navigated GuideWire, PointerShell instrument adaptor and FlexTube navigated suction and irrigation.

4 Dec 2014

$TxCell enrolls first patient in Ovasave phase IIb trial for treatment of refractory Crohn’s disease$

TxCell enrolls first patient in Ovasave phase IIb trial for treatment of refractory Crohn’s disease

TxCell SA, a biotechnology company developing novel and innovative, cost-effective personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that it has enrolled the first patient in its phase IIb clinical trial of its lead product Ovasave in refractory Crohn’s disease.

4 Dec 2014

Endocrinologist examines benefits and harms of testosterone therapy

An article in the latest edition of Australian Prescriber looks at the prescribing of testosterone, often used for ‘male menopause’ symptoms such as reduced energy, poor concentration and increased body fat. Over the past decade there has been a steep rise in the amount of testosterone dispensed in Australia and globally.

4 Dec 2014

Non-ergot derived dopamine agonists may be safe for the heart

Non-ergot derived dopamine agonists used to treat Parkinson's disease may be safe for the heart, according to preliminary research presented at EuroEcho-Imaging 2014 by Dr Hilal Erken Pamukcu, cardiologist at Ankara Diskapi Education and Research Hospital in Turkey.

4 Dec 2014

New technology reveals cellular gene transcription process in detail

A new technology that reveals cellular gene transcription in greater detail has been developed by Dr. Daniel Kaufmann of the University of Montreal Hospital Research Centre and the research team he directed. "This new research tool offers us a more profound view of the immune responses that are involved in a range of diseases, such as HIV infection. At the level of gene transcription, this had been difficult, complex and costly to do with current technologies, such as microscopy," explained the University of Montreal professor.

4 Dec 2014

New light-triggered strategy can provide accurate control over aptamer-based therapeutics

While aptamers—single-stranded nucleic acids—offer promise as drug-delivery tools for cancer treatment, it has proven difficult to get them to tumor cells at therapeutic levels.

4 Dec 2014

New chemical compound shows promise in restoring function lost to spinal cord injury

Case Western Reserve scientists have developed a new chemical compound that shows extraordinary promise in restoring function lost to spinal cord injury. The compound, which the researchers dubbed intracellular sigma peptide (ISP), allowed paralyzed muscles to activate in more than 80 percent of the animals tested.

4 Dec 2014

UC San Diego Health System named to The Leapfrog Group's list of Top Hospitals

For the second time, The Leapfrog Group has named UC San Diego Health System to its annual list of Top Hospitals. Awarded to hospitals nationwide for demonstrating excellence in hospital safety and quality, the Leapfrog Top Hospital award is an elite distinction given to less than seven percent of all eligible hospitals. The awards were announced on December 2, in Washington, D.C.

4 Dec 2014

Study reports effective treatment approach to inhibit herpes virus infection

A multi-institutional study reports an effective treatment approach to inhibit and keep latent viruses like herpes simplex from reactivating and causing disease. The work, whose lead author is the late James Hill, PhD, LSU Health New Orleans Professor and Director of Pharmacology and Infectious Disease at the LSU Eye Center, is published in the December 3, 2014, issue of Science Translational Medicine.

4 Dec 2014

Hospital News and Research

People with first-episode psychosis may benefit from medication treatment changes, study finds

Study: PET scanning strategy could help predict effectiveness of TB drugs

Study on hospital alarm fatigue records more than 2.5 million alarms in one month

New single-cell genetic profiling techniques help uncover variation in pluripotent stem cells

DePuy Synthes Spine receives FDA clearance to market VEPTR/VETPR II Devices for TIS treatment

SurgiQuest receives Most Promising Life Sciences Company of the Year award

Disease-associated malnutrition imposes economic burden on society

Fiagon's ENT Extended Instrument Set receives FDA approval

TxCell enrolls first patient in Ovasave phase IIb trial for treatment of refractory Crohn’s disease

Endocrinologist examines benefits and harms of testosterone therapy

Non-ergot derived dopamine agonists may be safe for the heart

New technology reveals cellular gene transcription process in detail

New light-triggered strategy can provide accurate control over aptamer-based therapeutics

New chemical compound shows promise in restoring function lost to spinal cord injury

UC San Diego Health System named to The Leapfrog Group's list of Top Hospitals

Study reports effective treatment approach to inhibit herpes virus infection

Study: Common prostate cancer therapy exposes low-risk patients to more adverse side effects

Researchers identify retrieval practice as useful strategy for improving memory among youth with TBI

Five speech pathology students from Griffith to take on jobs with Queensland Health

IQ linked to schizophrenia risk

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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