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Researchers reveal how migrating tumour cells produce protein that helps set up home in bones

Cancer cells that migrate to the bone acquire a unique trait: They start to express the protein cathepsin K. Researchers from the University of Freiburg and the BIOSS Centre for Biological Signalling Studies have now solved why it is important for the migrating cells to produce this protein.

17 Aug 2015

UT Arlington, UNTHSC researchers develop user-friendly system alerts for people with sleep apnea

Masks worn by those with sleep apnea can leak at night and be so uncomfortable that they often drive users away from treatment. But a new system being developed by researchers at UNT Health Science Center and The University of Texas at Arlington could make it easier for the estimated 18 million people with sleep apnea to get a good night's rest.

14 Aug 2015

Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

The National Institutes of Health has awarded $2.7 million to the Women's Medicine Collaborative to study the placenta and its function to determine whether changes in the placenta are linked to sleep abnormalities.

14 Aug 2015

Envarsus XR granted FDA orphan drug designation for prophylaxis of organ rejection in kidney transplant patients

Veloxis Pharmaceuticals A/S, today announced that Envarsus XR was granted Orphan Drug status by the U.S. Food and Drug Administration for prophylaxis of organ rejection in patients who convert from immediate-release tacrolimus. Envarsus XR received marketing authorization from the FDA on July 10, 2015.

14 Aug 2015

TKI outcomes ‘unfavourable’ in young CML patients

Adolescent and young adult patients with chronic myeloid leukaemia may have an unfavourable outcome on tyrosine kinase inhibitor therapy compared with their older counterparts, suggests a study of Japanese patients.

14 Aug 2015

Risk for endophthalmitis no higher with Avastin, finds study

Eye injections of the drug Avastin, used to treat retinal diseases, bring no greater risk of endophthalmitis, a potentially blinding eye infection, than injections with the much more expensive drug Lucentis made by the same company, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Their findings are published today in JAMA Ophthalmology.

14 Aug 2015

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

Many "medical foods" are designed to help manage patients with rare inborn errors of metabolism (IEMs), and can help prevent serious and life-threatening complications. However, such special foods may cause harm in some patients when their use is not carefully monitored and managed, according to a research team led by scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

14 Aug 2015

Cord Blood America’s 2015 second quarter revenue increases 39.0% to $1.41 million

Cord Blood America, Inc. today announced financial results for the second quarter ended June 30, 2015.

14 Aug 2015

Tips for preventing ticks, Lyme disease

When a mosquito decides to dine on your blood, you typically know it - there's pain, itch, and annoyance. Ticks, on the other hand, take a stealthier approach, burrowing into hard-to-spot areas and hanging around for hours or days at a time.

14 Aug 2015

MGH papers reveal the way anesthetics affect brains of older patients and children

Recent Massachusetts General Hospital (MGH) investigations into the neurobiology underlying the effects of general anesthesia have begun to reveal the ways different anesthetic agents alter specific aspects of the brain's electrical signals, reflected by EEG (electroencephalogram) signatures. While those studies have provided information that may lead to improved techniques for monitoring the consciousness of patients receiving general anesthesia, until now they have been conducted in relatively young adult patients.

14 Aug 2015

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Children born with the major congenital heart defect hypoplastic left heart syndrome (HLHS) often must undergo a series of corrective surgeries beginning at birth. While most have the standard three-stage Norwood procedure, a hybrid strategy has been introduced to offset some disadvantages associated with the Norwood surgeries. In a report in The Journal of Thoracic and Cardiovascular Surgery, investigators compare whether outcomes can be improved if an arterial shunt is used as a source of pulmonary blood flow rather than the more conventional venous shunt as part of the hybrid strategy of HLHS surgical reconstruction.

14 Aug 2015

Opioids produced by yeast; revealing the potential for cheaper pain relief

Researchers at Stanford University have genetically engineered yeast so it produces hydrocodone, a semi-synthetic opioid analgesic used in the United States for relief of moderate to severe pain.

14 Aug 2015

Improved method for building proteins into antibodies

Some proteins exist so fleetingly in the bloodstream that they can't be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute (TSRI) has devised an improved method for accomplishing this protein-engineering feat.

14 Aug 2015

Ontario nearing ambitious UN targets for ending AIDS epidemics

A new study suggests Ontario is nearing ambitious United Nations targets for ending the AIDS epidemics: By 2020, 90 per cent of all people living with HIV should know their HIV status, 90 per cent of all people diagnosed with HIV are receiving sustained antiretroviral drug therapy and 90 per cent of people on ART have a very low or undetectable levels of the virus.

14 Aug 2015

PHIV children may lack immunity against measles, mumps, and rubella despite vaccination

Between one-third and one-half of individuals in the United States who were infected with HIV around the time of birth may not have sufficient immunity to ward off measles, mumps, and rubella--even though they may have been vaccinated against these diseases.

14 Aug 2015

USC kidney researcher named recipient of ASN-AHA Young Investigator Award

Keck School of Medicine of the University of Southern California kidney researcher Janos Peti-Peterdi is the 2015 recipient of the ASN-AHA Young Investigator Award.

14 Aug 2015

TSRI-led team devises selection-based, protein-engineering method to work on obesity therapy

Some proteins exist so fleetingly in the bloodstream that they can’t be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute has devised an improved method for accomplishing this protein-engineering feat.

14 Aug 2015

Low birth weight, preterm birth increase schizophrenia risk in individuals with 22q11.2 deletion syndrome

Low birth weight and preterm birth appear to increase the risk of schizophrenia among individuals with a genetic condition called the 22q11.2 deletion syndrome, a new study from the Centre for Addiction and Mental Health (CAMH) shows.

14 Aug 2015

Researchers help explain how malaria infection increases children's risk of developing Burkitt's lymphoma

In equatorial Africa, a region of the globe known as the "lymphoma belt," children are ten times more likely than in other parts of the world to develop Burkitt's lymphoma, a highly aggressive blood cancer that can be fatal if left untreated. That area is also plagued by high rates of malaria, and scientists have spent the last 50 years trying to understand how the two diseases are connected.

14 Aug 2015

Combination of chemotherapy and immune-blocking drug could prevent cancer recurrence

Giving patients a drug that blocks part of the immune system from going into overdrive might help prevent cancer coming back in some people, according to research published today in Cancer Research.

13 Aug 2015

Blood News and Research

Researchers reveal how migrating tumour cells produce protein that helps set up home in bones

UT Arlington, UNTHSC researchers develop user-friendly system alerts for people with sleep apnea

Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

Envarsus XR granted FDA orphan drug designation for prophylaxis of organ rejection in kidney transplant patients

TKI outcomes ‘unfavourable’ in young CML patients

Risk for endophthalmitis no higher with Avastin, finds study

‘Medical foods’ for patients with rare IEMs may cause harm when not carefully managed

Cord Blood America’s 2015 second quarter revenue increases 39.0% to $1.41 million

Tips for preventing ticks, Lyme disease

MGH papers reveal the way anesthetics affect brains of older patients and children

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Opioids produced by yeast; revealing the potential for cheaper pain relief

Improved method for building proteins into antibodies

Ontario nearing ambitious UN targets for ending AIDS epidemics

PHIV children may lack immunity against measles, mumps, and rubella despite vaccination

USC kidney researcher named recipient of ASN-AHA Young Investigator Award

TSRI-led team devises selection-based, protein-engineering method to work on obesity therapy

Low birth weight, preterm birth increase schizophrenia risk in individuals with 22q11.2 deletion syndrome

Researchers help explain how malaria infection increases children's risk of developing Burkitt's lymphoma

Combination of chemotherapy and immune-blocking drug could prevent cancer recurrence

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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