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Inhibikase Therapeutics launches observational clinical study in patients who survived PML

Inhibikase Therapeutics, Inc. announces the launch of an observational clinical study in patients who contracted Progressive Multifocal Leukoencephalopathy (PML), the rare and often fatal brain infection that arises as an unintended side effect of some medications used for treatment of Multiple Sclerosis, Crohn's disease, Ulcerative Colitis and certain cancers of the blood and lymph.

13 Aug 2015

New study explains why statins are more beneficial than others in some cases

Statins' success in reducing atherosclerosis-related events has elevated the medications to wonder-drug status, with some researchers advocating for their wider use as a preemptive therapy for cardiovascular disease.

13 Aug 2015

Newly developed big data technique may have significant impact on health care

Rice University scientists have developed a big data technique that could have a significant impact on health care. The Rice lab of bioengineer Amina Qutub designed an algorithm called "progeny clustering" that is being used in a hospital study to identify which treatments should be given to children with leukemia.

13 Aug 2015

Tumor cells associated with pancreatic cancer work with each other to increase tumor spread

Tumor cells associated with pancreatic cancer often behave like communities by working with each other to increase tumor spread and growth to different organs. Groups of these cancer cells are better than single cancer cells in driving tumor spread, according to new research from the Perelman School of Medicine at the University of Pennsylvania published in Cancer Discovery online in advance of the print issue.

13 Aug 2015

McMaster University hematologist finds different limb loss syndromes

How people can develop limb gangrene and lose fingers and feet has baffled doctors for centuries. Now a McMaster University hematologist has identified different limb loss syndromes along with explanations for what is happening and what can be done about it.

13 Aug 2015

Penn Medicine experts say that health care innovation is about testing new ideas to promote better patient care

Health care has much to learn from innovative high-tech companies, but not in the way most people think, according to a Perspective published today in the New England Journal of Medicine and authored by innovation experts from the Perelman School of Medicine and the Wharton School at the University of Pennsylvania. Innovation, they say, can most effectively achieve meaningful outcomes by testing many new ideas quickly, cheaply, and contextually.

13 Aug 2015

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

A review of 15 years’ worth of data in a national pediatric medical database has documented a substantial increase in the rate of hospitalizations for children with a form of high blood pressure once most common in those with congenital heart disease.

13 Aug 2015

New research could help develop precision medicine for primary aldosteronism

Each of your kidneys wears a little yellow cap that helps keep your blood pressure in check, and much more. But in some people, it starts running amok, pumping out a hormone that sends blood pressure sky-high.

13 Aug 2015

Common marker can help identify patients at high risk for deadly cardiac events

A marker commonly used to determine if a patient is having a heart attack can also be used to identify stable patients at high risk for deadly cardiac events, according to a new study led by investigators at Brigham and Women's Hospital.

13 Aug 2015

Dynatronics granted U.S. patent for ThermoStim Probe

Dynatronics Corporation today announced its patent for "Systems and Methods for Providing a Thermo-electro-stimulation Probe Device" (US Patent No. 9,084,665) has been granted by the U.S. Patent and Trademark Office. This technology is incorporated in the company's ThermoStim Probe used in the delivery of therapeutic treatments.

12 Aug 2015

$AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion$

AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion

AbbVie, a global biopharmaceutical company, today announced that a Phase 2 trial of its investigational medicine venetoclax met its primary endpoint of achieving overall response rates in patients with relapsed/refractory or previously untreated chronic lymphocytic leukemia (CLL) with 17p deletion, according to an independent review analysis.

12 Aug 2015

Cold water immersion after strength training hinders muscle adaptation, study finds

If the thought of a post workout ice bath is enough to make you shiver, new research from QUT and The University of Queensland (UQ) will warm your heart.

12 Aug 2015

Researchers elucidate mechanism that induces skeletal muscle atrophy in patients with congestive heart failure

It is a paradox: Patients with advanced congestive heart failure lose skeletal muscle mass, but their heart muscles become enlarged to provide the body with an adequate supply of blood and thus with oxygen. It has long been known that the protein angiotensin II plays a villainous role in this process, but the exact mechanism has remained unclear.

12 Aug 2015

Delaying surgery until clinical triggers emerge leads to increased mortality in patients with mitral regurgitation

Patients with mitral regurgitation face a dilemma of whether to undergo corrective surgery early, when they might have no or few symptoms, or wait until their condition worsens. Current guidelines allow for watchful waiting until certain symptoms appear that would then "trigger" the decision to proceed with surgery.

12 Aug 2015

Study finds no added benefit for insulin degludec and liraglutide in type 2 diabetes

The fixed-ratio combination of the two drugs insulin degludec and liraglutide (trade name: Xultophy) has been approved since September 2014 for adults with type 2 diabetes mellitus. It is given as an injection in addition to other blood-glucose lowering drugs when these alone or in combination with basal insulin are insufficient to lower blood glucose levels.

12 Aug 2015

Gastric bypass surgery enhances energy expenditure

Gastric bypass surgery often leads to a sustained weight loss. Researchers at Sahlgrenska Academy have found part of the explanation: the operation enhances energy expenditure such that eating actually helps the person lose weight.

12 Aug 2015

Researcher study potential biomarker to determine patients at risk for aggressive breast cancer

Biomarkers are an important part in detecting certain cancers such as the BRCA gene in breast cancer and the PSA antigen in prostate cancer. They are easy to identify in a blood test and can help in diagnosing and giving a prognosis.

12 Aug 2015

Insulin pump users face less risk of dying from cardiovascular disease

People with type 1 diabetes who use insulin pump therapy face almost 50% less risk of dying from cardiovascular disease than those who take insulin by multiple daily injections. The British Medical Journal has published a study conducted at Sahlgrenska Academy.

12 Aug 2015

Testosterone administration not associated with atherosclerosis progression among older men

Among older men with low testosterone levels, testosterone administration for 3 years compared with placebo did not result in a significant difference in the rates of change in atherosclerosis (thickening and hardening of artery walls), nor was it associated with improved overall sexual function or health-related quality of life, according to a study in the August 11 issue of JAMA.

12 Aug 2015

New study reveals role of hydrogen sulfide gas in autoimmune disease

The immune system not only responds to infections and other potentially problematic abnormalities in the body, it also contains a built-in brake in the form of regulatory T cells, or Tregs. Tregs ensure that inflammatory responses don't get out of hand and do damage. In autoimmune diseases, sometimes these Treg cells don't act as they should.

12 Aug 2015

Blood News and Research

Inhibikase Therapeutics launches observational clinical study in patients who survived PML

New study explains why statins are more beneficial than others in some cases

Newly developed big data technique may have significant impact on health care

Tumor cells associated with pancreatic cancer work with each other to increase tumor spread

McMaster University hematologist finds different limb loss syndromes

Penn Medicine experts say that health care innovation is about testing new ideas to promote better patient care

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

New research could help develop precision medicine for primary aldosteronism

Common marker can help identify patients at high risk for deadly cardiac events

Dynatronics granted U.S. patent for ThermoStim Probe

AbbVie's venetoclax Phase 2 trial meets primary endpoint in patients with relapsed/refractory CLL with 17P deletion

Cold water immersion after strength training hinders muscle adaptation, study finds

Researchers elucidate mechanism that induces skeletal muscle atrophy in patients with congestive heart failure

Delaying surgery until clinical triggers emerge leads to increased mortality in patients with mitral regurgitation

Study finds no added benefit for insulin degludec and liraglutide in type 2 diabetes

Gastric bypass surgery enhances energy expenditure

Researcher study potential biomarker to determine patients at risk for aggressive breast cancer

Insulin pump users face less risk of dying from cardiovascular disease

Testosterone administration not associated with atherosclerosis progression among older men

New study reveals role of hydrogen sulfide gas in autoimmune disease

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