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Stem cells derived from bone marrow provide better quality of life to transplant patients

A large, nationwide study published in the journal JAMA Oncology found that people who received transplants of cells collected from a donor's bone marrow the original source for blood stem cell transplants, developed decades ago had better self-reported psychological well-being, experienced fewer symptoms of a common post-transplant side effect called graft-vs.-host disease and were more likely to be back at work five years after transplantation than those whose transplanted cells were taken from the donor's bloodstream.

17 Aug 2016

Modifying huntingtin protein protects against behavioral symptoms in Huntington's model mice

There is new hope in the fight against Huntington's disease. Scientists at the Gladstone Institutes discovered that changing a specific part of the huntingtin protein prevented the loss of critical brain cells and protected against behavioral symptoms in a mouse model of the disease.

16 Aug 2016

Researchers find new way to kill Staphylococcus aureus bacteria

Scientists have discovered a new way to attack Staphylococcus aureus bacteria. The team, from Imperial College London, have revealed how the bacteria regulates its salt levels.

16 Aug 2016

Study shows microRNA molecule prevents cancer cells from responding to chemotherapy treatment

Annually about 2000 Danish patients with colorectal cancer are treated with chemotherapy. Today, a range of different chemotherapeutic regimens are available. However, deciding which regimen to use is not easy.

16 Aug 2016

Latinos age more slowly than other ethnic groups, reveals UCLA study

A UCLA study is the first to show that Latinos age at a slower rate than other ethnic groups. The findings, published in the current issue of Genome Biology, may one day help scientists understand how to slow the aging process for everyone.

16 Aug 2016

Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows

Computers can be trained to be more accurate than pathologists in assessing slides of lung cancer tissues, according to a new study by researchers at the Stanford University School of Medicine.

16 Aug 2016

ISBI releases evidence-based practice guidelines to enhance and standardize burn care

Burns can be among the most devastating of injuries. Following the formulation of practice guidelines (PGs) that addressed the care and management of burn injuries in developed countries, the International Society for Burn Injuries has updated these recommendations to guide the improvement of care of burn patients in resource-limited settings (RLS).

16 Aug 2016

IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets

Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure.

16 Aug 2016

Researchers develop new nanorobotic agents to deliver drugs by targeting cancerous tumours

Researchers from Polytechnique Montréal, Université de Montréal and McGill University have just achieved a spectacular breakthrough in cancer research.

16 Aug 2016

Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations.

16 Aug 2016

German scientists develop new approach to prevent GvHD after bone marrow transplants

Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants.

16 Aug 2016

Researchers explain why secondary infection with MRSA kills influenza patients

Researchers have discovered that secondary infection with the Methicillin-resistant Staphylococcus aureus (MRSA) bacterium (or "superbug") often kills influenza patients because the flu virus alters the antibacterial response of white blood cells, causing them to damage the patients' lungs instead of destroying the bacterium.

16 Aug 2016

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients.

16 Aug 2016

New study uncovers how chromosomal changes impact tumor formation and growth

As with most cancers, triple-negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes.

16 Aug 2016

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

Before I explain the discovery, I would take a step back and explain an interesting event that takes place in the cancer cells. Normal cells follow a rapid and irreversible process to efficiently eradicate dysfunctional cells. This is a natural process by which damaged cells commit ‘suicide’. This process is known as apoptosis or programmed cell death.

15 Aug 2016

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

Dr. Qizhi Cathy Yao, professor of surgery, molecular virology and microbiology, and pathology & immunology at Baylor College of Medicine, has been awarded a National Institutes of Health grant to fund a collaborative project with Molecular Express, Inc.

12 Aug 2016

St. Jude scientists identify key innate immune sensor that attacks influenza virus

St. Jude Children's Research Hospital immunologists have identified the protein trigger in the body's quick-reaction innate immune system that specifically recognizes the influenza virus in infected cells and triggers their death.

12 Aug 2016

Glia cells may play role in regulating sugar intake into the brain, experts report

Researchers at Technical University of Munich discovered that our brain actively takes sugar from the blood. Prior to this, researchers around the world had assumed that this was a purely passive process.

12 Aug 2016

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

Scientists at The Institute of Cancer Research, London, have identified how an inherited genetic variant, associated with an increased risk of developing the most common type of leukaemia, helps cancer cells survive. The findings could lead to new ways to target the disease.

12 Aug 2016

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

iCell Gene Therapeutics today (Aug. 11) announced that the Food and Drug Administration has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL).

12 Aug 2016

Cell News and Research

Stem cells derived from bone marrow provide better quality of life to transplant patients

Modifying huntingtin protein protects against behavioral symptoms in Huntington's model mice

Researchers find new way to kill Staphylococcus aureus bacteria

Study shows microRNA molecule prevents cancer cells from responding to chemotherapy treatment

Latinos age more slowly than other ethnic groups, reveals UCLA study

Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows

ISBI releases evidence-based practice guidelines to enhance and standardize burn care

IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets

Researchers develop new nanorobotic agents to deliver drugs by targeting cancerous tumours

Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

German scientists develop new approach to prevent GvHD after bone marrow transplants

Researchers explain why secondary infection with MRSA kills influenza patients

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

New study uncovers how chromosomal changes impact tumor formation and growth

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

St. Jude scientists identify key innate immune sensor that attacks influenza virus

Glia cells may play role in regulating sugar intake into the brain, experts report

ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive

FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma

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