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Novel computational analysis of prostate cancer suggests potential targets for therapy

Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and proteins that enable prostate cancer cells to proliferate and evade treatment.

11 Aug 2016

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

A method for "silencing" RNA that emerged from a University of Wisconsin-Madison spinoff company is in clinical trials in Europe, Asia and the United States against hepatitis B, an infection that can destroy the liver.

11 Aug 2016

Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

Research from investigators at Rutgers Cancer Institute of New Jersey and Princeton University has identified a new approach to cancer therapy in cutting off a cancer cell's 'fuel supply' by targeting a cellular survival mechanism known as autophagy.

11 Aug 2016

Researchers find causal link between senescent cells and age-related osteoarthritis

Researchers at Mayo Clinic have reported a causal link between senescent cells — cells that accumulate with age and contribute to frailty and disease — and osteoarthritis in mice.

11 Aug 2016

SBP board member donates $1M for researchers to study pancreatic and prostate cancer

Sanford Burnham Prebys Medical Discovery Institute (SBP) has received a $1M donation from The Epstein Family Foundation for scientists to study pancreatic and prostate cancer.

10 Aug 2016

Researchers reprogram skin cells from diabetic foot ulcers to generate iPSCs

The potential to use a patient's own cells to treat non-healing chronic wounds - a serious complication of diabetes - took an important step forward as researchers successfully reprogrammed skin cells taken from diabetic foot ulcers to form induced pluripotent stem cells (iPSCs).

10 Aug 2016

Geneticists identify enzyme that regulates chromosome segregation during meiosis

GENETICISTS have identified an enzyme which regulates the production of sperm and egg cells in human reproduction.

10 Aug 2016

Gene mutation linked to impulsive drunken behaviour shields bearers from obesity, insulin resistance

University of Helsinki researchers have previously demonstrated that a point mutation in a gene of serotonin 2B receptor can render the carrier prone to impulsive behaviour, particularly when drunk.

10 Aug 2016

Penn study sheds light on role of essential compound in maintaining optimal muscle function

Maintaining proper levels of an essential helper molecule is crucial for optimal muscle function, according to a study led by Joseph Baur, PhD, an assistant professor of Physiology in the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2016

Olympics officials find potential new trend in doping among athletes

Olympics officials already contending with the illegal use of steroids among athletes are now being proactive about a potential new trend in performance enhancement: gene doping.

10 Aug 2016

ISCT selects London as host city for 2017 landmark conference to celebrate silver jubilee year

The International Society for Cellular Therapy, the global society of clinicians, researchers, regulatory specialists, technologists, and industry partners dedicated to the translation of cellular therapy into safe and effective therapies to improve patients’ lives, today announces they have awarded London as the host city for the landmark ISCT 2017 Annual Meeting to be held on May 3-6, at ExCeL London Exhibition and Convention Centre, UK to celebrate the Society’s 25th silver jubilee year. More than 1,600 international delegates are expected to attend.

10 Aug 2016

SLCU research institute uses Quorum PP3010T Cryo-SEM preparation system for plant biology research

Quorum Technologies, market and technology leaders in electron microscopy coating and cryogenic preparation products, report on plant biology research at the Sainsbury Laboratory, Cambridge UK, where their PP3010T Cryo-SEM preparation system is in routine use.

10 Aug 2016

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

Researchers have uncovered how genes identified from genome-wide association studies (GWAS) affect high-density lipoprotein cholesterol (HDL-C), a biomarker of cardiovascular disease, after comparing several animal models with human patient data.

10 Aug 2016

UH biologists developing strategies to help regenerate heart muscle cell formation

Cardiovascular diseases are the leading cause of death in the U.S. With one in every four deaths occurring each year, the five-year survival rate after a heart attack is worse than most cancers.

10 Aug 2016

Noninvasive approach using pulsed electric fields may reduce scarring after burn injuries

A Massachusetts General Hospital research team has reported that repeated treatment with pulsed electric fields - a noninvasive procedure that does not generate heat - may help reduce the development of scarring.

10 Aug 2016

Researchers develop machine-learning program that helps identify hundreds of ASD-related genes

Investigators eager to uncover the genetic basis of autism could now have hundreds of promising new leads thanks to a study by Princeton University and Simons Foundation researchers.

9 Aug 2016

Whitehead Institute researchers identify cellular mechanisms involved in pre-mouth array formation

Whitehead Institute researchers have identified the pre-mouth array--an area of the developing face in embryonic frogs--that "unzips" to surround the mouth opening. Their work highlights the precision necessary to create the mouth and identifies the cellular mechanisms that drive its formation.

9 Aug 2016

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from progressive fibrosis and result in sudden death.

9 Aug 2016

Scientists improve potential weapon to fight against autoimmune disorders

With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from inflammatory bowel disease or organ transplant rejection.

9 Aug 2016

Cell News and Research

Novel computational analysis of prostate cancer suggests potential targets for therapy

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

Researchers find causal link between senescent cells and age-related osteoarthritis

SBP board member donates $1M for researchers to study pancreatic and prostate cancer

Researchers reprogram skin cells from diabetic foot ulcers to generate iPSCs

Geneticists identify enzyme that regulates chromosome segregation during meiosis

Gene mutation linked to impulsive drunken behaviour shields bearers from obesity, insulin resistance

Penn study sheds light on role of essential compound in maintaining optimal muscle function

Olympics officials find potential new trend in doping among athletes

ISCT selects London as host city for 2017 landmark conference to celebrate silver jubilee year

SLCU research institute uses Quorum PP3010T Cryo-SEM preparation system for plant biology research

Rare genetic variations linked to severe porphyria

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

UH biologists developing strategies to help regenerate heart muscle cell formation

Noninvasive approach using pulsed electric fields may reduce scarring after burn injuries

Researchers develop machine-learning program that helps identify hundreds of ASD-related genes

Whitehead Institute researchers identify cellular mechanisms involved in pre-mouth array formation

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Scientists improve potential weapon to fight against autoimmune disorders

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