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All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

Can preclinical COVID-19 models help unlock mystery of long-COVID?

In a recently published article in the journal PLOS PATHOGENS, scientists have summarized acute and prolonged clinical manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The review also provides an overview of the potency and utility of preclinical animal models to understand the mechanistic details of acute and long coronavirus disease 2019 (COVID-19).

8 Sep 2022

Licorice compounds proposed as effective candidates for treatment of COVID-19

Researchers describe the different mechanisms by which licorice active ingredients target SARS-CoV-2.

8 Sep 2022

Biosynthetic proteins show promise as SARS-CoV-2 antivirals targeting spike protein

Researchers developed an αRep series specific to the RBD of the SARS-CoV-2 S, which could easily adapt to work stably against SARS-CoV-2 variants at a low cost.

8 Sep 2022

How does SARS-CoV-2 infection and vaccination impact human immune memory?

Researchers review current knowledge regarding the generation of immune memory responses and their durability post-infection and vaccination.

7 Sep 2022

How does SARS-CoV-2 affect the male genitourinary system?

In a recent paper published in the American Journal of Clinical and Experimental Urology, researchers reviewed existing data on the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male genitourinary (GU) tract.

7 Sep 2022

How does SARS-CoV-2 infection impact fertility in men?

In a recent review published in the journal Endocrines, researchers summarized existing literature findings on the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the male reproductive system and fertility.

7 Sep 2022

Plant production of nanobodies that neutralize the interaction between ACE2 receptor and SARS-CoV-2 spike protein

Researchers demonstrated the production of nanobodies against SARS-CoV-2 spike protein.

7 Sep 2022

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Researchers performed the photocatalytic mapping of the SARS-CoV-2 spike protein-host cell membrane interactions.

7 Sep 2022

Study suggests entry of SARS-CoV-2 requires an acidic pH

Researchers carried out real-time single-virion tracking in three dimensions to study the mechanisms and requirements of membrane attachment and fusion of SARS-CoV-2 with the host cell.

6 Sep 2022

Auranofin inhibits SARS-CoV-2 replication

In a new ISCIENCE journal study, scientists identified an FDA-approved NF-κB inhibitor, Auranofin, which can also control inflammation.

6 Sep 2022

The possible association between SARS-CoV-2, ACE2, TMPRSS2, and skin manifestations

A new study analyzed the possibility of penetration of SARS-CoV-2 into the skin.

5 Sep 2022

How does ACE2 expression in target cells affect neutralization by antibodies to different spike epitopes?

Researchers evaluated how ACE2 expression in target cells impacts neutralization.

2 Sep 2022

A rapid and efficient method of identifying neutralizing nanobodies directed against SARS-CoV-2

A recent PLoS ONE study detected neutralizing nanobodies against SARS-CoV-2 from nanobody phage display libraries and via in vitro and ex vivo high-throughput screenings.

2 Sep 2022

N501Y mutation and SARS-CoV-2 spike protein-angiotensin-converting enzyme-2 binding

In a new study, researchers assessed the effects of N501Y mutation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein on binding to angiotensin-converting enzyme-2 (ACE-2).

1 Sep 2022

What is the infectivity of SARS-CoV-2 Omicron BA.2.75 variant?

Researchers recently assessed the infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2.75 variant compared to preexisting variants.

30 Aug 2022

Researchers report the exceptional binding and neutralizing potency of an ACE2 decoy against SARS-CoV-2 variants

Researchers explored the activity of an ACE2 decoy against SARS-CoV-2 Omicron variant.

30 Aug 2022

Study finds strong evidence for the ability of SARS-CoV-2 to infect human sperm in vitro

Researchers explored the molecular and cellular mechanisms of SARS-CoV-2 infection.

30 Aug 2022

What are the effects of e-cigarettes and their constituents on SARS-CoV-2 infection?

In a new study, researchers evaluated whether e-cigarette (EC) aerosols promoted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

29 Aug 2022

COVID-19 pandemic: An epidemiological update

Epidemics and pandemics have been frightening the human chase again and again. SARS, H1N1, Ebola, and more have exposed their real face in the past, but with every such outbreak.

25 Aug 2022

ACE2 News and Research

All SARS-CoV-2 variants neutralized by a potent new antibody

Can preclinical COVID-19 models help unlock mystery of long-COVID?

Licorice compounds proposed as effective candidates for treatment of COVID-19

Biosynthetic proteins show promise as SARS-CoV-2 antivirals targeting spike protein

How does SARS-CoV-2 infection and vaccination impact human immune memory?

How does SARS-CoV-2 affect the male genitourinary system?

How does SARS-CoV-2 infection impact fertility in men?

Plant production of nanobodies that neutralize the interaction between ACE2 receptor and SARS-CoV-2 spike protein

Photocatalyst-based ViraMap platform maps SARS-CoV-2 spike protein interactions on the cell surface

Study suggests entry of SARS-CoV-2 requires an acidic pH

Auranofin inhibits SARS-CoV-2 replication

The possible association between SARS-CoV-2, ACE2, TMPRSS2, and skin manifestations

How does ACE2 expression in target cells affect neutralization by antibodies to different spike epitopes?

A rapid and efficient method of identifying neutralizing nanobodies directed against SARS-CoV-2

N501Y mutation and SARS-CoV-2 spike protein-angiotensin-converting enzyme-2 binding

What is the infectivity of SARS-CoV-2 Omicron BA.2.75 variant?

Researchers report the exceptional binding and neutralizing potency of an ACE2 decoy against SARS-CoV-2 variants

Study finds strong evidence for the ability of SARS-CoV-2 to infect human sperm in vitro

What are the effects of e-cigarettes and their constituents on SARS-CoV-2 infection?

COVID-19 pandemic: An epidemiological update

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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