Avian influenza is an infection caused by avian (bird) influenza (flu) viruses. These influenza viruses occur naturally among birds. Wild birds worldwide carry the viruses in their intestines, but usually do not get sick from them. However, avian influenza is very contagious among birds and can make some domesticated birds, including chickens, ducks, and turkeys, very sick and kill them.
"Less than two weeks after Chinese officials released the genetic sequence of a new type of bird flu [H7N9], U.S. vaccine experts are well on the way to making a vaccine to protect people against it," NBC News's "Vitals" blog reports (Fox, 4/10).
IDRI, a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles, today announced that they will be presenting positive interim Phase I clinical results for their H5N1 Avian Influenza VLP vaccine candidate "H5N1 vaccine" at the World Vaccine Congress.
The WHO "is talking with the Chinese government about sending international experts to China to help investigate a new bird flu strain that has sickened at least 24 people, killing seven of them," the Associated Press reports.
In a Foreign Policy opinion piece, Laurie Garrett, senior fellow for global health at the Council on Foreign Relations, recounts recent events in China, including the discovery of hundreds of dead pigs, ducks, and geese in rivers and the diagnosis of several human cases of a new strain of avian influenza, H7N9, and she writes, "[T]his could be how pandemics begin."
Until now most experimental vaccines against the highly lethal H5N1 avian influenza virus have lacked effectiveness. But a new vaccine has proven highly effective against the virus when tested in both mice and ferrets. It is also effective against the H9 subtype of avian influenza.
"Cambodia reported on Wednesday that another four-year-old girl has contracted avian influenza H5N1, becoming the seventh person who infected the virus in 2013," Xinhua reports.
"It's been a rough flu season this winter in the United States and Europe, but it could be worse. A lot worse," science writer Carl Zimmer states in National Geographic's "Phenomena: The Loom" blog.
PaxVax, Inc., which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced positive results in a Phase 1 clinical trial for its oral, replicating adenovirus serotype 4 (Ad4) vector vaccine for H5N1 (avian flu).
"Two more children have died in Cambodia of bird flu, bringing the number of fatal cases this year to four and the number of cases overall to five," the Associated Press/Wall Street Journal reports, noting only three cases were reported in all of 2012. "WHO says bird flu, also known as avian influenza, or H5N1, has killed 360 other people worldwide since surfacing in 2003," with most cases "linked to contact with infected poultry," the news agency writes.
Noting that a nearly yearlong moratorium on H5N1 avian influenza research, put in place "because of safety and terrorism concerns," was lifted recently, a New York Times editorial states, "We wish we could be as sanguine as they are that all the earlier concerns have been dealt with."
"Almost a year after they announced it, leading influenza researchers are ending a voluntary moratorium on certain types of controversial experiments involving the H5N1 avian influenza virus."
Researchers report for the first time the seroprevalence of three strains of avian influenza viruses in pigs in southern China, but not the H5N1 avian influenza virus. Their research, published online ahead of print in the Journal of Clinical Microbiology, has implications for efforts to protect the public health from pandemics.
CIDRAP News reports on a two-day meeting at the National Institutes of Health during which "researchers, biosecurity experts, and others" discussed the "crafting of a framework for funding H5N1 avian influenza gain-of-function studies." The meeting "is the latest chapter in an intense scientific controversy that was triggered by the publication of two recent studies involving lab-engineered H5N1 strains that showed signs of being transmissible in mammals," according to the news service.
"Researchers are giving a mixed reception to a draft U.S. government plan to do more stringent funding reviews of certain kinds of H5N1 avian influenza research -- and perhaps even require some studies to be kept secret," Science reports.
Researchers recently found that a single dose of a vaccine being developed by Medicago, Inc., a publicly traded biopharmaceutical company, could protect against not only the avian influenza (H5N1) strain it was designed for, but also another H5N1 strain and a strain of a different flu subtype, called H2N2.
Rising sea levels, melting glaciers, more intense rainstorms and more frequent heat waves are among the planetary woes that may come to mind when climate change is mentioned. Now, two University of Michigan researchers say an increased risk of avian influenza transmission in wild birds can be added to the list.
The Infectious Disease Research Institute (IDRI), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), announce that they have been cleared by the U.S. Food and Drug Administration (FDA) to initiate a Phase 1 clinical trial for an H5N1 Avian Influenza VLP vaccine candidate.
A major collaboration between US research centers has highlighted three factors that could ultimately determine whether an outbreak of influenza becomes a serious epidemic that threatens national health. The research suggests that the numbers in current response plans could be out by a factor of two or more depending on the characteristics of the particular pandemic influenza.
"Dissatisfied with the government's handling of two research papers on mutant forms of avian influenza," Rep. Jim Sensenbrenner (R-Wisc.) on Wednesday "said that the lack of a cohesive policy for handling risky research funded by the National Institutes of Health (NIH) and other federal agencies could necessitate new laws, a situation that researchers have been trying to avoid," the Nature News Blog reports.
VaxInnate Corporation today announced that enrollment has commenced in a Phase I clinical trial to evaluate VAX161, its novel H5 vaccine candidate in development for the prevention of pandemic avian influenza or bird flu. VaxInnate is a biotechnology firm pioneering breakthrough technology for developing novel vaccines.
Terms
While we only use edited and approved content for Azthena
answers, it may on occasions provide incorrect responses.
Please confirm any data provided with the related suppliers or
authors. We do not provide medical advice, if you search for
medical information you must always consult a medical
professional before acting on any information provided.
Your questions, but not your email details will be shared with
OpenAI and retained for 30 days in accordance with their
privacy principles.
Please do not ask questions that use sensitive or confidential
information.
Read the full Terms & Conditions.