Immune Response News and Research

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SARS-CoV-2 immunity due to prior infection or vaccination is similar, study says

A new study finds that the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection is low following one episode of the infection.

11 Jul 2021

Initial SARS-CoV-2 vaccination response may predict BNT162b2 booster response, but not AZD1222

A new study finds that the antibody titer values prior to the booster dose of the BNT162b2 vaccine can predict the final antibody response after two doses.

11 Jul 2021

Mice study identifies pathways that link high-fat diet to atherosclerosis

It's long been known that a high-fat diet can lead to clogged arteries, but we have only recently begun to learn in detail how the process works. A new study in experimental mice could go a long way to finding treatments to keep arteries open and flowing.

9 Jul 2021

Scientists analyze the sensitivity of SARS-CoV-2 Delta variant to monoclonal antibodies

The Delta variant was detected for the first time in India in October 2020 and has since spread throughout the world.

9 Jul 2021

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

A new study from Queen Mary University of London has demonstrated that immune cells can be stimulated to assemble into special structures within pancreatic cancer such that, at least in a pre-clinical model, researchers can demonstrate an improvement in the efficacy of chemotherapy.

9 Jul 2021

Durable antibody response at least 8 months following vaccination with J&J COVID vaccine

A recent study by a team of scientists at Beth Israel Deaconess Medical Center and Janssen Vaccines & Prevention has demonstrated that humoral and cellular immunity elicited by the coronavirus disease 2019 (COVID-19) vaccine Ad26.COV2.S remains active for at least eight months.

9 Jul 2021

Intranasal COVID-19 vaccine protects animals against lethal COVID-19 infection

In a new study assessing the potential of a single-dose, intranasal COVID-19 vaccine, a team from the University of Iowa and the University of Georgia found that the vaccine fully protects mice against lethal COVID-19 infection.

8 Jul 2021

Novel tool enables multi-resolution characterization of molecular taxonomies

The discovery of novel groups or categories within diseases, organisms and biological processes and their organization into hierarchical relationships are important and recurrent pursuits in biology and medicine, which may help elucidate group-specific vulnerabilities and ultimately novel therapeutic interventions.

8 Jul 2021

Scientists study how our immune system responds to COVID-19 variants

Australian scientists researching how our immune system responds to COVID-19 have revealed that those infected by early variants in 2020 produced sustained antibodies, however, these antibodies are not as effective against contemporary variants of the virus.

8 Jul 2021

New biological pathway selectively controls how key immune cells mature into functional components

Immunologists at St. Jude Children's Research Hospital have identified a biological pathway that selectively controls how key immune cells, called T follicular helper cells, mature into functional components of the immune system.

8 Jul 2021

Discovery of SARS-CoV-2–induced pathways uncovers groundbreaking drug repurposing strategies

A new study has been published in Science Advances that exploits proteomics datasets to develop an agnostic network for SARS-CoV-2–induced pathways, thereby unveiling novel targets and potential repurposing strategies.

7 Jul 2021

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Together with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called APOBEC proteins are important factors in the body's immune response and offer fast and effective protection against a large number of DNA and RNA viruses.

7 Jul 2021

COVID-19 vaccination may be stemming evolution of “fitter” SARS-CoV-2 variants

Researchers in the United States and India have presented the first known evidence that the rollout of coronavirus disease 2019 (COVID-19) vaccination is restricting the evolutionary and immune escape pathways accessible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jul 2021

Moderna’s COVID-19 vaccine elicits durable T cell memory and antibody responses

Researchers in the United States have shown that Moderna’s mRNA-1273 coronavirus disease 2019 (COVID-19) vaccine induces durable antibody and T cell responses to the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are comparable to those seen in cases of COVID-19 caused by natural SARS-CoV-2 infection.

6 Jul 2021

Research team identifies a way to improve immune response during viral infections

Melbourne researchers have identified a way to improve the immune response in the face of severe viral infections.

6 Jul 2021

Eight new research projects to explore COVID-19 variants of concern in Canada

Eight new research projects are getting underway in Canada to investigate COVID-19 variants of concern (VOCs) and variants of interest (VOIs).

6 Jul 2021

Chemotherapy destabilizes gut microbiome in cancer patients

New research in BMC Cancer has shown myelosuppressive chemotherapy destabilizes gut microbiome in patients with solid organ cancers.

6 Jul 2021

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

Scientists at UC San Francisco have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases, potentially paving the way for developing less expensive cellular therapies to treat diseases for which there are currently few viable options.

6 Jul 2021

Study examines evolution and avidity of anti-SARS-CoV-2 IgG antibodies after mRNA vaccination

New research released on the medRxiv* preprint server has measured antibody responses in 71 mRNA vaccinated adults (54 vaccinated with Pfizer and 17 vaccinated with Moderna).

6 Jul 2021

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

A new study has been released on the bioRxiv* preprint server, which deals with a comprehensive survey on alternative splicing concerning SARS-CoV-2 infection. This study has also included two other betacoronavirurses (SARS-CoV and MERS), a control set of unrelated viruses, and a bacterium, namely, Streptococcus pneumonia. The study findings suggest that several cellular parameters are affected owing to a betacoronavirus infection, which in turn affects some genes and invariably various biological functions.

6 Jul 2021

Immune Response News and Research

SARS-CoV-2 immunity due to prior infection or vaccination is similar, study says

Initial SARS-CoV-2 vaccination response may predict BNT162b2 booster response, but not AZD1222

Mice study identifies pathways that link high-fat diet to atherosclerosis

Scientists analyze the sensitivity of SARS-CoV-2 Delta variant to monoclonal antibodies

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

Durable antibody response at least 8 months following vaccination with J&J COVID vaccine

Intranasal COVID-19 vaccine protects animals against lethal COVID-19 infection

Novel tool enables multi-resolution characterization of molecular taxonomies

Scientists study how our immune system responds to COVID-19 variants

New biological pathway selectively controls how key immune cells mature into functional components

Discovery of SARS-CoV-2–induced pathways uncovers groundbreaking drug repurposing strategies

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

COVID-19 vaccination may be stemming evolution of “fitter” SARS-CoV-2 variants

Moderna’s COVID-19 vaccine elicits durable T cell memory and antibody responses

Research team identifies a way to improve immune response during viral infections

Eight new research projects to explore COVID-19 variants of concern in Canada

Chemotherapy destabilizes gut microbiome in cancer patients

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

Study examines evolution and avidity of anti-SARS-CoV-2 IgG antibodies after mRNA vaccination

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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