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Researchers identify important therapeutic target for small cell lung cancer

UT Southwestern Medical Center researchers have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.

22 Jul 2016

Study suggests failure of specialised beta cells may lead to diabetes

The significant role of beta cell 'hubs' in the pancreas has been demonstrated for the first time, suggesting that diabetes may due to the failure of a privileged few cells, rather than the behaviour of all cells.

21 Jul 2016

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds

A key gene enables the repair of injured muscle throughout life. This is the finding of a study in mice led by researchers at NYU Langone Medical Center and the University of Colorado at Boulder, and published online July 21 in Cell Reports.

21 Jul 2016

BET inhibitor treatment decreases lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage.

21 Jul 2016

Combining ART with immune-enhancing treatment may destabilize HIV reservoirs

Although antiretroviral therapy (ART) can reduce the amount of HIV in the blood to an undetectable level in most chronically infected people, it cannot eliminate reservoirs of HIV that persist in latently infected immune cells.

21 Jul 2016

Scientists demonstrate synapses between specific neuron types form clusters

The cerebral cortex resembles a vast switchboard. Countless lines carrying information about the environment, for example from the sensory organs, converge in the cerebral cortex.

21 Jul 2016

Study identifies ADAM33 gene as novel target for preventing asthma

Scientists at the University of Southampton have discovered a potential and novel way of preventing asthma at the origin of the disease, a finding that could challenge the current understanding of the condition.

21 Jul 2016

Improving efficiency of health facilities could extend ART to many people living with HIV

Health facilities in Kenya, Uganda, and Zambia could extend life-sustaining antiretroviral therapy (ART) to hundreds of thousands of people living with HIV if facilities improved the efficiency of service delivery.

21 Jul 2016

HSS researchers launch new study to find if stem cell treatment could help people with knee arthritis

Researchers at Hospital for Special Surgery have launched a study to determine if a treatment using stem cells could help people with painful knee arthritis.

21 Jul 2016

Researchers identify genetic causes underlying higher rate of melanoma in men

A study led by researchers at Universitat Jaume I de Castellón has identified one of the genetic causes underlying the higher rate of melanoma in men. The results have been published in Biology of Sex Differences.

21 Jul 2016

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

A collaboration between the University of Leicester and global pharmaceutical company GlaxoSmithKline has been established to discover and develop novel medicines to treat aggressive forms of blood cancer.

21 Jul 2016

New study offers hypothesis why obese patients fare worse during cancer treatment

Across many cancer types, obese patients fare worse than leaner patients. Now a University of Colorado Cancer Center study published in the journal Cell Stem Cell offers a compelling hypothesis why: researchers found that leukemia stem cells "hide" in fatty tissue, even transforming this tissue in ways that support their survival when challenged with chemotherapy. It is as if leukemia stem cells not only use fatty tissue as a robbers' cave to hide from therapy, but actively adapt this cave to their liking.

21 Jul 2016

Researchers show porous silicon nanoparticles could be harmless to diagnose and treat cancer

The Lomonosov Moscow State University researchers in collaboration with their German colleagues have succeeded in proving that silicon nanoparticles can be applied to diagnose and cure cancer.

21 Jul 2016

Scientists find promising new method to detect and treat recurrence of ovarian cancer

Researchers at the Mayo Clinic Center for Individualized Medicine have found a promising new way to monitor and treat recurrence of ovarian cancer -- a hard-to-detect disease that claims many lives.

21 Jul 2016

New study shows women with ADHD likely to have many mental, physical health problems

Women with ADHD are much more likely to have a wide range of mental and physical health problems in comparison to women without ADHD, according to a new study from researchers at the University of Toronto.

21 Jul 2016

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

A new scientific study has identified why colorectal cancer cells depend on a specific nutrient, and a way to starve them of it. Over one million men and women are living with colorectal cancer in the United States.

21 Jul 2016

Adding new monoclonal antibody to chemotherapy improves survival in soft-tissue sarcoma patients

Adding a novel monoclonal antibody therapy to traditional chemotherapy increased median survival by nearly a year in patients with advanced sarcoma, a lethal soft-tissue cancer.

21 Jul 2016

Clinical trial to assess safety of using umbilical cord cells to treat macular degeneration

UIC is part of a national phase 2 clinical trial to evaluate the safety and tolerability of using cells derived from multipotent umbilical cord cells to treat age-related macular degeneration, the most common cause of vision loss in people over 55.

21 Jul 2016

TSRI study reveals new approach to intervene in deadly disease

In a new study, scientists at The Scripps Research Institute have identified drug candidates that can boost a cell's ability to catch the "typos" in protein production that can cause a deadly disease called amyloidosis.

From Paxman 21 Jul 2016

Scientists develop new optical fiber-based probe for brain temperature measurements

The brain is the most temperature-sensitive organ in the body. Even small deviations in brain temperature are capable of producing profound effects--including behavioral changes, cell toxicity, and neuronal cell death. The problem faced by researchers and clinicians is how to measure and understand the

20 Jul 2016

Cell News and Research

Researchers identify important therapeutic target for small cell lung cancer

Study suggests failure of specialised beta cells may lead to diabetes

Key gene controls ability of adult stem cells to regenerate muscle after injury, study finds

BET inhibitor treatment decreases lung inflammation in mice

Combining ART with immune-enhancing treatment may destabilize HIV reservoirs

Scientists demonstrate synapses between specific neuron types form clusters

Study identifies ADAM33 gene as novel target for preventing asthma

Improving efficiency of health facilities could extend ART to many people living with HIV

HSS researchers launch new study to find if stem cell treatment could help people with knee arthritis

Researchers identify genetic causes underlying higher rate of melanoma in men

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

New study offers hypothesis why obese patients fare worse during cancer treatment

Researchers show porous silicon nanoparticles could be harmless to diagnose and treat cancer

Scientists find promising new method to detect and treat recurrence of ovarian cancer

New study shows women with ADHD likely to have many mental, physical health problems

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

Adding new monoclonal antibody to chemotherapy improves survival in soft-tissue sarcoma patients

Clinical trial to assess safety of using umbilical cord cells to treat macular degeneration

TSRI study reveals new approach to intervene in deadly disease

Scientists develop new optical fiber-based probe for brain temperature measurements

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