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Penn study provides more insights into cardiovascular side effects of breast cancer drug

A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

14 Jul 2016

Losing weight can lower levels of some proteins linked to tumor growth

Overweight and obese women who lost weight through diet and exercise lowered the levels of certain proteins in their blood that play a role in angiogenesis, the process of blood vessel growth that can promote the growth and survival of cancer cells

14 Jul 2016

New treatment approach may benefit relapsed post-transplant blood cancer patients

For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognosis.

13 Jul 2016

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

The Wistar Institute is pleased to announce that the National Institutes of Health has awarded a nearly $23 million Martin Delaney Collaboratories for HIV Cure Research grant to the BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy, a consortium of top HIV researchers led by co-principal investigators Luis J. Montaner, D.V.M., D.Phil., director of the HIV-1 Immunopathogenesis Laboratory at The Wistar Institute Vaccine Center, and James L. Riley, Ph.D., research associate professor at the Perelman School of Medicine at the University of Pennsylvania.

13 Jul 2016

Study finds high prevalence of tinnitus among adolescents

Teenagers are increasingly experiencing tinnitus, often a symptom of hearing loss, as a result of using ear buds to listen to music for long periods every day, as well as frequenting very noisy places like nightclubs, discos and rock concerts, according to a study performed in Brazil.

13 Jul 2016

Sugar-binding protein galectin-9 could be new weapon to fight HIV

The ultimate impediment to a cure for HIV infection is the presence of latent, HIV-infected cells, which can reawaken and produce new virus when antiretroviral drug therapy is stopped.

13 Jul 2016

Changes in cavefish metabolism could lead to new insights into diabetes

Cavefish that live in dark caves with only sporadic access to food show symptoms similar to diabetes, but don't appear to experience any health problems.

13 Jul 2016

Researchers discover new biological pathway involved in Alzheimer's disease

Researchers have identified a new biological pathway involved in Alzheimer's disease. In experiments using fruit flies, blocking the pathway reduced the death of brain cells, suggesting that interfering with the pathway could represent a promising new strategy to treat the disease in human patients.

13 Jul 2016

Researchers study how skin stem cells respond to forces

All cells share the same genetic code, no matter if they are skin or brain cells. However, these cells are exposed to very different types of mechanical environments and mechanical stresses.

13 Jul 2016

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

New ultra-fast approach to modeling protein interactions may pave way for drug development

Protein-protein interactions (PPIs) are the basis of cellular functions, and when these processes are compromised diseases such as cancer emerge. For years scientists have tried with mixed success to map out PPIs to understand cellular processes.

13 Jul 2016

Researchers identify new mechanism by which bacteria outsmarts immune system

Bacteria are rapidly developing resistance mechanisms to combat even the most effective antibiotics.

13 Jul 2016

Maturitas provides new holistic model of care for healthy menopause

A new position statement by the European Menopause and Andropause Society published in the journal Maturitas provides a holistic model of care for healthy menopause.

13 Jul 2016

Scientists discover new biological defense system against pathogenic microorganisms

For the first time in the world, a group of researchers discovered a human immune receptor, which detects the invasion of pathogenic microorganisms.

13 Jul 2016

New multicomponent reactions to develop active compounds against sleeping sickness

Multicomponent reactions are protocols that ease the chemical synthesis of new compounds, and are particularly important to gain molecules with biological activity as therapeutic agents against several pathogens.

13 Jul 2016

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.

12 Jul 2016

Researchers identify mechanisms triggering hypergammaglobulinemia

Some autoimmune diseases and persistent infections are characterized by high levels of antibodies in the blood. But what are the causes of this hypergammaglobulinemia? A team headed by INRS's Professor Simona Stäger has successfully identified the mechanisms triggering the phenomenon.

12 Jul 2016

Cell News and Research

Penn study provides more insights into cardiovascular side effects of breast cancer drug

Losing weight can lower levels of some proteins linked to tumor growth

New treatment approach may benefit relapsed post-transplant blood cancer patients

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

Study finds high prevalence of tinnitus among adolescents

Sugar-binding protein galectin-9 could be new weapon to fight HIV

Changes in cavefish metabolism could lead to new insights into diabetes

Researchers discover new biological pathway involved in Alzheimer's disease

Researchers study how skin stem cells respond to forces

Scientists identify timing of major metabolic shift in developing neurons

New ultra-fast approach to modeling protein interactions may pave way for drug development

Researchers identify new mechanism by which bacteria outsmarts immune system

Maturitas provides new holistic model of care for healthy menopause

Scientists discover new biological defense system against pathogenic microorganisms

New multicomponent reactions to develop active compounds against sleeping sickness

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Researchers identify mechanisms triggering hypergammaglobulinemia

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Lifting lighter weights many times can be effective alternative way to gain muscle strength

Research on Flattop protein could provide starting point for regenerative diabetes therapies

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