Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

White coat hypertension, masked hypertension increase cardiovascular events over the years

Patients whose blood pressures spikes in the doctor's office but not at home, and patients whose blood pressure spikes at home but not in the doctor's office, suffer more heart attacks, heart failure, and strokes than patients with normal blood pressures in both settings, UT Southwestern Medical Center researchers have found.

10 Nov 2015

Intensive management of high blood pressure reduces rates of cardiovascular disease, lowers risk of death

Jackson T. Wright Jr., MD, PhD, and researchers from University Hospitals Case Medical Center presented new results from the Systolic Blood Pressure Intervention Trial (SPRINT) showing that in patients at high risk for cardiovascular events, targeting a systolic blood pressure of less than 120 mm Hg resulted in lower rates of fatal and non-fatal major events or death compared to targeting systolic blood pressure to the usually recommended target of less than 140 mm Hg.

10 Nov 2015

Isosorbide mononitrate does not increase HFpEF patients' daily activity level

Heart failure patients with preserved ejection fraction (HFpEF) -- where the heart becomes stiff and cannot relax or fill properly -- did not have increased exercise tolerance after taking isosorbide mononitrate, compared to a placebo, according to a study presented today at the American Heart Association's Scientific Sessions 2015.

10 Nov 2015

Type 2 diabetes drug significantly reduces hospitalizations, death from heart failure

For the first time, research shows that a type 2 diabetes drug significantly reduces hospitalizations and death from heart failure.

10 Nov 2015

New funding for Centenary's life saving research

The Centenary Institute has welcomed the Federal Government’s announcement of funding for 9 new and innovative medical research projects via the latest round of NHMRC grant rounds funding, officially confirmed today.

9 Nov 2015

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

Armaron Bio, a Melbourne-based drug development company focused on heart failure and other diseases, is pleased to announce that it has begun its Phase II clinical trial for NP202, its novel lead candidate drug for heart failure.

9 Nov 2015

Heart attack patients diagnosed and treated for diabetes experience improved cardiac outcomes

People with heart problems often have diabetes, which puts them at greater risk for heart attacks, heart failure and stroke. Now, a new study has found that ensuring heart attack patients are promptly diagnosed and treated for diabetes makes a significant difference in improving their cardiac outcomes.

9 Nov 2015

Diabetes drug liraglutide ineffective in patients with advanced heart failure

In an attempt to correct defects in the energy generation that contributes to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure. Despite improvements in blood sugar control, the therapy did not improve the clinical stability or pumping action of the heart in patients with advanced heart failure.

9 Nov 2015

Better understanding of hibernation could help researchers develop treatments for cardiac disease

Wintry weather means hats and scarves for some mammals, and hibernation for others. Hibernation dramatically lowers body temperatures, heart rates and oxygen consumption -- things that would be fatal to other animals. A team reports in ACS' Journal of Proteome Research a study of the proteins and genes that allow squirrels' hearts to stay healthy during the winter.

5 Nov 2015

CVIA journal launched at the opening ceremony of 26th GW-ICC meeting

Cardiovascular Innovations and Applications (CVIA), a new journal affiliated with the Great Wall-International Congress of Cardiology, was introduced today at the opening ceremony of GWICC by Congress Chairman Prof. Changsheng Ma.

3 Nov 2015

UAB performs life-saving TAVR procedure on Selma resident

In the late 1990s, Earnest Tate was named the first black police chief of Selma, Alabama. Nearly 20 years later, Tate is retired and works on his family farm in the city where he made history.

31 Oct 2015

Researchers use strain-gauge plethysmography system to assess cerebral outflow in microgravity

On Earth, blood flows down from a person's brain back toward the heart thanks in part to gravity, but very little is known about how this flow happens in microgravity.

31 Oct 2015

Miriam Hospital enrolling local participants for Parachute implant clinical trial to treat heart failure

The Miriam Hospital is actively recruiting local participants for a U.S. clinical trial of the Parachute device for treating heart failure. The study is focused on determining if the new minimally invasive catheter-based device can slow the progression of heart failure, reduce repeat hospitalizations and death, and significantly improve quality of life for patients who experience enlargement of the left ventricle after a heart attack.

31 Oct 2015

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented October 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego. This is the first study in humans to associate opioid blockade with improved survival.

28 Oct 2015

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Mast Therapeutics, Inc., a clinical-stage biopharmaceutical company leveraging its molecular adhesion and sealant technology (MAST) platform to develop novel therapies for sickle cell disease, heart failure, and stroke, announced that it has initiated its Phase 2 study of vepoloxamer for the treatment of patients with chronic heart failure.

26 Oct 2015

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

The U.S. Food and Drug Administration today approved Yondelis (trabectedin), a chemotherapy, for the treatment of specific soft tissue sarcomas (STS) – liposarcoma and leiomyosarcoma – that cannot be removed by surgery (unresectable) or is advanced (metastatic).

24 Oct 2015

Henry Ford Hospital pulmonologist advocates for raising the smoking age to 21

Henry Ford Hospital pulmonologist Daniel Ouellette, M.D., who during his 31-year career in medicine has seen the harmful effects of smoking on his patients, advocates for raising the smoking age to 21.

22 Oct 2015

Current approach to blood pressure treatment can't restore cardiovascular risk to ideal levels, study suggests

Treating out-of-control blood pressure with antihypertensive medication can greatly reduce your risk for heart attack, stroke and heart failure, but the current approach to treatment can't undo all of the previous damage or restore cardiovascular disease risk to ideal levels, a new Northwestern Medicine study suggests.

22 Oct 2015

Veltassa (patiromer for oral suspension) gets FDA approval for treatment of hyperkalemia

The U.S. Food and Drug Administration today approved Veltassa (patiromer for oral suspension) to treat hyperkalemia, a serious condition in which the amount of potassium in the blood is too high.

22 Oct 2015

The American Heart Association and Heart Rhythm Society Unite to Improve Cardiovascular Research, Care

The American Heart Association and Heart Rhythm Society today announced a collaboration designed to advance research and improve the delivery of care for people with an irregular heartbeat known as atrial fibrillation (AFib).

20 Oct 2015

Heart Failure News and Research

Further Reading

White coat hypertension, masked hypertension increase cardiovascular events over the years

Intensive management of high blood pressure reduces rates of cardiovascular disease, lowers risk of death

Isosorbide mononitrate does not increase HFpEF patients' daily activity level

Type 2 diabetes drug significantly reduces hospitalizations, death from heart failure

New funding for Centenary's life saving research

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

Heart attack patients diagnosed and treated for diabetes experience improved cardiac outcomes

Diabetes drug liraglutide ineffective in patients with advanced heart failure

Better understanding of hibernation could help researchers develop treatments for cardiac disease

CVIA journal launched at the opening ceremony of 26th GW-ICC meeting

UAB performs life-saving TAVR procedure on Selma resident

Researchers use strain-gauge plethysmography system to assess cerebral outflow in microgravity

Miriam Hospital enrolling local participants for Parachute implant clinical trial to treat heart failure

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

FDA approves Yondelis (trabectedin) for treatment of specific soft tissue sarcomas

Henry Ford Hospital pulmonologist advocates for raising the smoking age to 21

Current approach to blood pressure treatment can't restore cardiovascular risk to ideal levels, study suggests

Veltassa (patiromer for oral suspension) gets FDA approval for treatment of hyperkalemia

The American Heart Association and Heart Rhythm Society Unite to Improve Cardiovascular Research, Care

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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