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Blocking Slit2 protein prevents blood vessel development that causes vasoproliferative ocular diseases

Vasoproliferative ocular diseases are responsible for sight loss in millions of people in the industrialised countries. Many patients do not currently respond to the treatment offered, which targets a specific factor, VEGF. A team of Inserm researchers at the Vision Institute (Inserm/CNRS/Pierre and Marie Curie University), in association with a team from the Yale Cardiovascular Research Center, have demonstrated in an animal model that blocking another protein, Slit2, prevents the pathological blood vessel development that causes these diseases.

22 Apr 2015

Data from pacritinib Phase 3 PERSIST-1 trial in patients with myelofibrosis to be highlighted at ASCO

CTI BioPharma Corp. and Baxter International Inc. today announced that data from the randomized Phase 3 PERSIST-1 trial evaluating the investigational agent pacritinib in patients with myelofibrosis will be highlighted in a late-breaking oral presentation at the upcoming American Society of Clinical Oncology 2015 Meeting (May 29-June 2, 2015 in Chicago, Ill).

From Baxter International Inc. 22 Apr 2015

Gene therapy reduces infectious complications in children, teens with Wiskott-Aldrich syndrome

In a small study that included seven children and teens with Wiskott-Aldrich syndrome, a rare immunodeficiency disorder, use of gene therapy resulted in clinical improvement in infectious complications, severe eczema, and symptoms of autoimmunity, according to a study in the April 21 issue of JAMA, a theme issue on child health.

22 Apr 2015

Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

The incidence of a potentially life-threatening complication of diabetes, diabetic ketoacidosis, in youth in Colorado at the time of diagnosis of type 1 diabetes increased by 55 percent between 1998 and 2012, suggesting a growing number of youth may experience delays in diagnosis and treatment, according to a study in the April 21 issue of JAMA, a theme issue on child health.

22 Apr 2015

Study calls for effective strategies to contain potential HDV epidemic in high-risk populations

Researchers from Taiwan determined that individuals with human immunodeficiency virus (HIV) infection or those who inject illicit drugs have a higher risk of becoming infected with the hepatitis D virus (HDV) in that country.

22 Apr 2015

Scientists identify protein that could help tame severe inflammation

Researchers have identified a protein that offers a new focus for developing targeted therapies to tame the severe inflammation associated with multiple sclerosis (MS), colitis and other autoimmune disorders.

22 Apr 2015

James Shapiro's latest research could soon mark new standard for diabetes treatment

James Shapiro, one of the world's leading experts in emerging treatments of diabetes, can't help but be excited about his latest research. The results he says, could soon mark a new standard for treatment--not only in diabetes, but in several other diseases as well.

22 Apr 2015

Researchers uncover methylated DNA markers that may lead to noninvasive cancer screening

A team of Mayo Clinic researchers has succeeded in identifying the source of cancer in patients' gastrointestinal tracts by analyzing DNA markers from tumors. The results open the possibility that doctors could one day be able to screen for cancer anywhere in the body with a noninvasive blood test or stool sample.

22 Apr 2015

IUPUI researcher awarded NIH grant to study neuroscience underlying obstructive sleep apnea

Sleep apnea affects an estimated 25 million adults in the United States and is associated with increased risk of hypertension, stroke, health attack and heart failure.

22 Apr 2015

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Individuals with type 2 diabetes, who are resistant to insulin, have an excess blood glucose level, which they are now trying to reduce using a new class of diabetes drugs known as the gliflozins.

22 Apr 2015

Men with prostate cancer benefit from BRCA-targeting drug

Men with prostate cancer benefit from treatment with the pioneering drug olaparib - the first cancer drug to target inherited mutations - according to the results of a major trial presented today (Tuesday).

22 Apr 2015

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

UC Davis Assistant Professor Mark Huising is a recipient of The Hartwell Foundation 2014 Individual Biomedical Research Award to support his early-stage research toward a cure for juvenile diabetes. Diabetes affects 10 percent of the entire United States population, including approximately a million children. Remarkably, 40 children every day receive the diagnosis of diabetes.

22 Apr 2015

EuroPRevent congress to focus on cardiovascular disease

While death rates from heart disease in Europe have more than halved in many countries and in most population groups since the early 1980s, heart disease remains by far the leading cause of death.

22 Apr 2015

University of Birmingham researchers identify new way to tackle chronic diseases

Researchers from the University of Birmingham have identified an important new way in which our immune systems are regulated, and hope that understanding it will help tackle the debilitating effects of type 1 diabetes, rheumatoid arthritis and other serious diseases.

22 Apr 2015

Cardio3 BioSciences reports absence of short term adverse events in first patient following NKG2D CAR T-cell infusion

Cardio3 BioSciences, soon to be renamed Celyad, a leader in engineered cell-therapy treatments today announced the infusion of the first patient enrolled in the Company’s Phase I clinical trial evaluating the safety and feasibility of its NKG2D CAR T-cell therapy, in cancer patients suffering from acute myeloid leukemia (AML) or multiple myeloma (MM).

22 Apr 2015

Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Upsher-Smith Laboratories, Inc. presented data from a 52-week, open-label extension study (PREVAIL OLE) showing that Qudexy XR (topiramate) extended-release capsules offered a long-term adjunctive treatment option with a favorable tolerability profile for a high proportion of patients with refractory partial-onset seizures (POS).

21 Apr 2015

Data presented at AACR 2015 recognizes value of EKF PointMan technology for assessing lung cancer mutation status

The PointMan EGFR DNA enrichment kit, a novel method for selective amplification of genotype specific sequences.

From EKF Diagnostics 21 Apr 2015

Bio-Rad grants Beckman Coulter exclusive distribution rights for access HIV and Hepatitis C assays

Bio-Rad is extending its agreement with Beckman Coulter and has named the company exclusive global distributor of Bio-Rad’s Access HIV combo assay and the Access hepatitis C virus (HCV) assay in select geographies...

From Beckman Coulter Diagnostics 21 Apr 2015

Cincinnati Children's pediatric allergist offers tips to combat allergies

One of the problems that parents may have during the springtime is deciphering whether their children's sneezing is due to a cold or allergies.

21 Apr 2015

New study shows regular consumption of yogurt not linked to health-related quality of life

Dietary recommendations support the consumption of dairy products as part of a healthy diet. However, after a Spanish study involving more than 4,000 people analysed the relationship between the regular intake of yogurt and health-related quality of life, it declared that there was no link with the improvement of the physical and mental parameters analysed.

21 Apr 2015

Blood News and Research

Blocking Slit2 protein prevents blood vessel development that causes vasoproliferative ocular diseases

Data from pacritinib Phase 3 PERSIST-1 trial in patients with myelofibrosis to be highlighted at ASCO

Gene therapy reduces infectious complications in children, teens with Wiskott-Aldrich syndrome

Incidence of potentially life-threatening diabetes complication increasing among youth in Colorado

Study calls for effective strategies to contain potential HDV epidemic in high-risk populations

Scientists identify protein that could help tame severe inflammation

James Shapiro's latest research could soon mark new standard for diabetes treatment

Researchers uncover methylated DNA markers that may lead to noninvasive cancer screening

IUPUI researcher awarded NIH grant to study neuroscience underlying obstructive sleep apnea

New class of drugs targeting blood glucose level could benefit individuals with type 2 diabetes

Men with prostate cancer benefit from BRCA-targeting drug

UC Davis assistant professor wins Hartwell Foundation award to explore treatment for juvenile diabetes

EuroPRevent congress to focus on cardiovascular disease

University of Birmingham researchers identify new way to tackle chronic diseases

Cardio3 BioSciences reports absence of short term adverse events in first patient following NKG2D CAR T-cell infusion

Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Data presented at AACR 2015 recognizes value of EKF PointMan technology for assessing lung cancer mutation status

Bio-Rad grants Beckman Coulter exclusive distribution rights for access HIV and Hepatitis C assays

Cincinnati Children's pediatric allergist offers tips to combat allergies

New study shows regular consumption of yogurt not linked to health-related quality of life

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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