Appetite News and Research

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Fructose metabolism by the brain increases food intake and obesity

The journal Biochemical and Biophysical Research Communications (BBRC), published by Elsevier, will publish an important review this week online, by M. Daniel Lane and colleagues at Johns Hopkins, building on the suggested link between the consumption of fructose and increased food intake, which may contribute to a high incidence of obesity and Type 2 diabetes.

25 Mar 2009

Experimental Parkinson's therapy may have robust weight-loss effect

A growth factor used in clinical experiments to rescue dying brain cells in Parkinson patients may cause unwanted weight loss if delivered to specific areas of the brain, according to University of Florida researchers in the March online edition of Molecular Therapy.

24 Mar 2009

Discovery of new molecular mechanism for the processing of endocannabinoids

Dale Deutsch, Ph.D., Professor of Biochemistry and Cell Biology at Stony Brook University and colleagues discovered a new molecular mechanism for the processing of endocannabinoids, brain compounds similar to THC, the active ingredient in marijuana, and essential in physiological processes such as pain, appetite, and memory.

24 Mar 2009

FDA approves Symbyax for treatment-resistant depression

The U.S. Food and Drug Administration (FDA) has approved a new indication for Symbyax (olanzapine and fluoxetine HCl capsules), Eli Lilly and Company has announced.

23 Mar 2009

Why low GI diet makes you feel full

Eating a meal with a low GI (glycaemic index) increases gut hormone production which leads to suppression of appetite and the feeling of fullness.

17 Mar 2009

Discovery of new mechanism for the processing of endocannabinoids

New research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, has identified a new mechanism for the processing of endocannabinoids, natural brain compounds similar to THC, the active ingredient in marijuana.

17 Mar 2009

Shire withdraws European application for Daytrana (Methylphenidate Transdermal System)

Shire plc has announced that it has decided to withdraw the European Marketing Authorization Application (MAA) for Daytrana (methylphenidate transdermal system) for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).

16 Mar 2009

Body clock regulates energy levels in cells

UC Irvine researchers have discovered that circadian rhythms - our own body clock - regulate energy levels in cells.

12 Mar 2009

Salt could be 'nature's antidepressant' according to new research

Most people consume far too much salt, and a University of Iowa researcher has discovered one potential reason we crave it: it might put us in a better mood.

11 Mar 2009

Metastatic bone disease patients can walk in Lazarus' footsteps

Osteoplasty - a highly effective minimally invasive procedure to treat the painful effects of metastatic bone disease by injecting bone cement to support weakened bones - provides immediate and substantial pain relief, often presenting individuals who are suffering terribly with the miraculous so-called "Lazarus effect," according to researchers at the Society of Interventional Radiology's 34th Annual Scientific Meeting.

10 Mar 2009

Measuring quality of life in patients with hereditary kidney disease

A commonly used questionnaire that measures quality of life is not sensitive enough to pick up mental and physical problems experienced by patients with autosomal dominant polycystic kidney disease (ADPKD), according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).

4 Mar 2009

Heart-healthy diets that reduce calorie intake promote long-term weight loss

Heart-healthy diets that reduce calorie intake - regardless of differing proportions of fat, protein, or carbohydrate - can help overweight and obese adults achieve and maintain weight loss, according to a study funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, and published Feb. 26, 2009, in the New England Journal of Medicine.

26 Feb 2009

GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

GlaxoSmithKline has announced initiation and dosing of the first patient of the Phase III clinical trial programme to evaluate the efficacy, safety and tolerability of the investigational GLP-1 (Glucagon-like peptide 1) agonist Syncria (albiglutide) in men and women with type 2 diabetes.

18 Feb 2009

Groundbreaking study reveals how enzymes in the cell cooperate to make fat

These enzymes are integrated into a single molecular complex known as fatty acid synthase. This complex is regarded as a potential target for developing new anti-obesity and anti-cancer drugs.

11 Feb 2009

Drinking lots of soda raises risk for early kidney disease in women

Women who drink two or more cans of soda pop per day are nearly twice as likely to show early signs of kidney disease, a recent study has found.

9 Feb 2009

UT Southwestern develops medically supervised liquid diet program

UT Southwestern Medical Center's bariatric program has developed a medically supervised program using a specially designed liquid protein diet for people looking to lose weight with or without surgery.

9 Feb 2009

Pathologically elevated blood fat levels in obesity: Researchers discover molecular causes

Scientists at the German Cancer Research Center have discovered a mechanism in liver metabolism that is responsible for pathologically elevated blood fat levels found in severe metabolic disorders.

9 Feb 2009

New research may lead to new pharmacologic approaches to treating obesity

Scientists at the University of North Carolina at Chapel Hill School of Medicine have discovered a gene that when mutated causes obesity by dampening the body's ability to burn energy while leaving appetite unaffected.

5 Feb 2009

Nothing silent about the way ovarian cancer kills

A new study by Australian scientists has revealed that far from being a silent killer, most women diagnosed with ovarian cancer had one or two unusual and persistent symptoms before they were diagnosed.

3 Feb 2009

Study finds vitamin use is highest in children who don't need them

A study by UC Davis researchers published in the February 2009 issue of the Archives of Pediatric & Adolescent Medicine has found that most of the healthy children and teenagers in the United States who are taking daily vitamin and mineral supplements probably don't need them.

2 Feb 2009