Immune Response News and Research

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CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

A new study published on the bioRxiv* server describes the changes in the representation of a subset of activated monocytes in this group of patients.

23 Jun 2021

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Often patients suffering from COVID-19 (coronavirus disease) show striking immune dysregulation - causing increased morbidity and mortality. Mechanisms for adaptive immune disturbance, lymphopenia, and thromboinflammation in COVID-19 are still poorly understood.

23 Jun 2021

Can antioxidants help manage neurological complications in COVID-19?

In a recent study published in Antioxidants, researchers evaluated the use of antioxidants as potential adjuvants for the treatment of COVID-19.

23 Jun 2021

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

A recent study published in Frontiers in Immunology focuses on the roles of the SADS-CoV N protein in IFN suppression during infection.

23 Jun 2021

Higher levels of antibodies from COVID-19 mRNA vaccine compared to natural SARS-CoV-2 infection

Researchers found antibody levels in mRNA vaccinated individuals varied with age, gender, and previous coronavirus disease (COVID-19) infection.

23 Jun 2021

Longitudinal study finds SARS-CoV-2 neutralizing antibodies decline a year after infection

Research led by Xin Zheng of Huazhong University of Science and Technology in Wuhan, China, found that about 90% of patients who recovered from COVID-19 continued to have IgG antibodies targeting the N-domain and receptor-binding domain of the spike protein. However, approximately 43% of patients showed signs of neutralizing antibody activity.

23 Jun 2021

Vaccine side effects should be viewed as a sign of efficacy, say immunologists

The rapid development of safe and efficacious vaccines against SARS-CoV-2 has offered hope that the global COVID-19 pandemic may soon be under control. However, vaccinations remain incomplete in many developed nations, and lag further still in the developing world.

23 Jun 2021

mRNA COVID-19 vaccines may increase patients' concerns about side effects

Vivid photos of the red "COVID arm" rash and reports of facial swelling in patients who have received dermatological fillers after Pfizer-BioNTech or Moderna vaccination for COVID-19 may increase patients' concerns about mRNA vaccine side effects and contribute to vaccine hesitancy.

23 Jun 2021

Albumin supplementation improves human fertility, fights infection

A new University of California, Irvine-led study reveals albumin (Alb), among the most abundant proteins in the body, activates a proton channel (hHv1), also widespread in the body, giving sperm the ability to penetrate and fertilize an egg, and allowing white blood cells to secrete large amounts of inflammatory mediators to fight infection.

22 Jun 2021

Is Rand Paul mixing up the vaccine message for Covid survivors?

Last week, Sen. Rand Paul (R-Ky.) posted a Twitter thread asserting that people who have survived a Covid-19 infection were unlikely to be reinfected and have better immunity against variants than those who have been vaccinated against — but not infected by — SARS-CoV-2, the virus that causes Covid.

22 Jun 2021

Use of nanotherapeutics in treating coronavirus diseases

Despite advancements in medicine, viral infections still pose a huge threat to human health and are a significant concern for global public health systems.

22 Jun 2021

Smoother silicone breast implants can reduce inflammation and other immune system reactions

According to researchers at Johns Hopkins Medicine, the Massachusetts Institute of Technology (MIT) and Rice University in Houston, silicone breast implants with a smoother surface design have less risk of producing inflammation and other immune system reactions than those with more roughly textured coatings.

22 Jun 2021

Clinicians report cases of rare neurological disorder following COVID-19 vaccination

In two separate articles in the Annals of Neurology, clinicians in India and England report cases of a rare neurological disorder called Guillain-Barre? syndrome after individuals were vaccinated against COVID-19.

22 Jun 2021

POSTECH research team develops plant-based, adjuvant-free avian influenza vaccine

The avian influenza, an acute viral infectious disease that occurs in poultry such as chickens, ducks, and migratory birds, has been reported to be transmittable to humans.

21 Jun 2021

Researchers analyze how breast implant surfaces influence immune response

Rice University bioengineers collaborated on a six-year study that systematically analyzed how the surface architecture of breast implants influences the development of adverse effects, including an unusual type of lymphoma.

21 Jun 2021

Discovery provides new target to make melanomas more vulnerable to anti-cancer treatments

Hypoxia, or the inadequate oxygenation of a tissue, is a condition occurring frequently in all solid tumors such as melanoma skin cancer.

21 Jun 2021

Study shows a robust immune response to COVID-19 vaccine in breastfeeding health workers

A recent study by researchers from Poland, published in the journal Vaccines, shows how levels of IgA and IgG antibodies specific to the spike glycoprotein of SARS-CoV-2 increase in both breast milk and serum samples of mothers following vaccination against COVID-19 – with important implications for further vaccine planning endeavors.

21 Jun 2021

Study reviews natural drug candidates for potential treatment of COVID-19

A recent paper in the Saudi Journal of Biological Sciences seeks to open up new approaches by reviewing a list of compounds derived from plants and other natural sources, which have potential inhibitory activity against the coronavirus.

21 Jun 2021

Viral phosphoesterases (including in CoVs) can restrict antiviral innate immunity

An interesting new study describes the activities of a family of viral enzymes called two-histidine-phosphoesterases (2H-PEs), found in coronaviruses (CoVs) and rotaviruses, as well as a mammalian A-kinase anchoring protein enzyme, AKAP7, that shares the same function. Together called 2’,5’-PEs, these enzymes all break down 2’,5’-oligoadenylate compounds that activate the antiviral enzyme ribonuclease L (RNase L).

21 Jun 2021

A World First: sequencing polyclonal antibodies using only proteomics

News-Medical speaks to Bin Ma, President of Rapid Novor, about their latest research that sequenced polyclonal antibodies using only proteomics.

From Rapid Novor Inc 21 Jun 2021

Immune Response News and Research

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Can antioxidants help manage neurological complications in COVID-19?

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

Higher levels of antibodies from COVID-19 mRNA vaccine compared to natural SARS-CoV-2 infection

Longitudinal study finds SARS-CoV-2 neutralizing antibodies decline a year after infection

Vaccine side effects should be viewed as a sign of efficacy, say immunologists

mRNA COVID-19 vaccines may increase patients' concerns about side effects

Albumin supplementation improves human fertility, fights infection

Is Rand Paul mixing up the vaccine message for Covid survivors?

Use of nanotherapeutics in treating coronavirus diseases

Smoother silicone breast implants can reduce inflammation and other immune system reactions

Clinicians report cases of rare neurological disorder following COVID-19 vaccination

POSTECH research team develops plant-based, adjuvant-free avian influenza vaccine

Researchers analyze how breast implant surfaces influence immune response

Discovery provides new target to make melanomas more vulnerable to anti-cancer treatments

Study shows a robust immune response to COVID-19 vaccine in breastfeeding health workers

Study reviews natural drug candidates for potential treatment of COVID-19

Viral phosphoesterases (including in CoVs) can restrict antiviral innate immunity

A World First: sequencing polyclonal antibodies using only proteomics

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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