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Researchers explore impact of installing alcohol ignition interlock devices in vehicles

If every new car made in the United States had a built-in blood alcohol level tester that prevented impaired drivers from driving the vehicle, how many lives could be saved, injuries prevented, and injury-related dollars left unspent?

23 Mar 2015

Study shows how PDT for pancreatic cancer can be included in physician practice without significant cost

Late stage pancreatic cancer benefits from photodynamic therapy (PDT) but the resources needed for the usual accompanying dosimetry present barriers, Dartmouth researchers Jonathan T. Elliott, PhD and Brian C. Pogue, PhD have mitigated by using common clinical technologies.

23 Mar 2015

Researchers identify new role for VEGFA that may help target metastatic neuroblastoma

Healthy bone is continuously involved in a dynamic process that includes bone deposition and bone resorption.

23 Mar 2015

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

The DNA you inherit from your parents contributes to the physical make-up of your body -- whether you have blue eyes or brown, black hair or red, or are male or female.

23 Mar 2015

Study finds no statistical difference between CTA and functional stress tests

A new type of CT scan initially costs slightly less than the traditional stress test to diagnose blocked coronary arteries in patients with chest pain, but its lower cost did not translate into medical care savings over time, according to an analysis by Duke Medicine researchers.

23 Mar 2015

Discovery may lead to new potential treatment for drug-resistant melanoma

In the last several years, targeted therapies - drugs that directly impact specific genes and proteins involved in the progression of cancer - have been approved for a wide variety of cancers, including melanoma, the deadliest form of skin cancer. Now, researchers at The Wistar Institute have discovered one way in which melanoma becomes resistant to a particular form of targeted therapy, and understanding this phenomenon may lead to a new melanoma target or prompt new designs of these treatments.

23 Mar 2015

Anticoagulant drug bivalirudin shows mixed results in MATRIX trial

Patients with acute coronary syndrome undergoing angioplasty who received the anticoagulant drug bivalirudin did not show significant improvements in either of two co-primary endpoints--a composite of rate of death, heart attack or stroke at 30 days, or a composite of those events plus major bleeding--as compared to patients receiving standard anticoagulation therapy, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

23 Mar 2015

Study: Blood tests for women taking spironolactone to treat hormonal acne are unnecessary

A new study by researchers at Brigham and Women's Hospital has found that for young, healthy women taking spironolactone to treat hormonal acne, frequent office visits and blood draws are an unnecessary health care expense.

23 Mar 2015

MRD-directed therapy helps boost survival of young leukemia patients

Measuring the concentration of leukemia cells in patient bone marrow during the first 46 days of chemotherapy should help boost survival of young leukemia patients by better matching patients with the right intensity of chemotherapy. St. Jude Children's Research Hospital investigators led the research, which appears in the March 20 edition of the journal Lancet Oncology.

22 Mar 2015

Experts call for global review of sepsis guidelines

Experts are calling for a global review of guidelines used to diagnose sepsis, after a study found one in eight patients with infections severe enough to need admission to an Intensive Care Unit in Australia and New Zealand, did not meet current criteria.

22 Mar 2015

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases.

21 Mar 2015

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Amgen today announced that an application seeking marketing approval of Repatha (evolocumab) for the treatment of high cholesterol has been submitted for review to the Ministry of Health, Labour and Welfare in Japan.

21 Mar 2015

Two-year data show continued survival advantage for self-expanding TAVR

Two-year data show a continued survival advantage for self-expanding transcatheter aortic valve replacement (TAVR) over standard surgery in high-risk patients with severe aortic stenosis, according to research presented at the American College of Cardiology's 64th Annual Scientific Session.

20 Mar 2015

New anti-clotting therapy no better than established anticoagulants

A novel therapy that would allow doctors to turn the body's blood-clotting ability off and on in a more controlled way was about as effective as established anticoagulants in patients undergoing angioplasty but was associated with higher rates of moderate to severe bleeding, according to an analysis of data from a terminated Phase III trial presented at the American College of Cardiology's 64th Annual Scientific Session.

20 Mar 2015

Healthcare systems miss life-saving treatments learnt on battlefield

Trauma is responsible for more global deaths annually than HIV, malaria and tuberculosis combined. Yet healthcare systems in many countries are missing out on life-saving treatments learnt on the battlefield, according to a review by King's College London and published today in the Journal of the Royal Society of Medicine.

20 Mar 2015

Discovery raises potential of blood test that can help diagnose osteoarthritis, rheumatoid

The first blood test for osteoarthritis could soon be developed, thanks to research by the University of Warwick.

20 Mar 2015

New strategies to improve screening rates for colorectal cancer in low-income populations

Since the colonoscopy was developed more than four decades ago, the screening procedure for colorectal cancer has undoubtedly saved millions of lives.

20 Mar 2015

Researchers develop noninvasive method to detect kidney cancer early

If kidney cancer is diagnosed early — before it spreads — 80 percent of patients survive. However, finding it early has been among the disease's greatest challenges.

20 Mar 2015

MRI more accurate, safe and less painful than liver biopsy in measuring total body iron balance

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have demonstrated that MR imaging of the liver is more accurate than liver biopsy in determining total body iron balance in patients with sickle cell disease and other disorders requiring blood transfusion therapy.

20 Mar 2015

Living near greened vacant lots reduces stress

Greening vacant lots may be associated with biologic reductions in stress, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. Residents who walked near newly greened vacant lots had significantly lower heart rates compared to walking near a blighted, or neglected, vacant lot.

20 Mar 2015

Blood News and Research

Researchers explore impact of installing alcohol ignition interlock devices in vehicles

Study shows how PDT for pancreatic cancer can be included in physician practice without significant cost

Researchers identify new role for VEGFA that may help target metastatic neuroblastoma

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

Study finds no statistical difference between CTA and functional stress tests

Discovery may lead to new potential treatment for drug-resistant melanoma

Anticoagulant drug bivalirudin shows mixed results in MATRIX trial

Study: Blood tests for women taking spironolactone to treat hormonal acne are unnecessary

MRD-directed therapy helps boost survival of young leukemia patients

Experts call for global review of sepsis guidelines

Hypermethylation serves as protective barrier inhibiting development of ALS, FTD

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Two-year data show continued survival advantage for self-expanding TAVR

New anti-clotting therapy no better than established anticoagulants

Healthcare systems miss life-saving treatments learnt on battlefield

Discovery raises potential of blood test that can help diagnose osteoarthritis, rheumatoid

New strategies to improve screening rates for colorectal cancer in low-income populations

Researchers develop noninvasive method to detect kidney cancer early

MRI more accurate, safe and less painful than liver biopsy in measuring total body iron balance

Living near greened vacant lots reduces stress

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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