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Aging reduces axonal regeneration after spinal cord injury

Older Americans are increasingly active, and this lifestyle shift has contributed to the rise in average age of a person experiencing a spinal cord injury. The changing demographic calls for a better understanding of how aging impacts recovery and repair after a spinal cord injury.

1 Apr 2016

Tumor suppressor p53 gene twice as likely to be defective in autistic children

A large study by researchers with the UC Davis MIND Institute has found that a gene whose role is to suppress cellular damage from environmental stressors is nearly twice as likely to be defective in children with autism spectrum disorder (ASD), and that the deficit is also present in their fathers.

1 Apr 2016

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

The U.S. Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).

31 Mar 2016

Commonly used fungicides could cause gene expression changes in brain cells

Scientists at the UNC School of Medicine have found a class of commonly used fungicides that produce gene expression changes similar to those in people with autism and neurodegenerative conditions, including Alzheimer's disease and Huntington's disease.

31 Mar 2016

Remotely tracking patients' eye gaze could help identify children with ASD

A study to be published in the April 2016 issue of the Journal of the American Academy of Child and Adolescent Psychiatry reports that eye tracking can differentiate children with autism spectrum disorder (ASD) from children without ASD but with other developmental problems (non-ASD).

31 Mar 2016

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Researchers at the University of Pittsburgh School of Medicine and Arts & Sciences have designed a more effective version of an FDA-approved epilepsy drug with the potential for fewer side effects, according to a study published on March 22 in Molecular Pharmacology. The experimental agent also could prove to be a treatment for tinnitus and other disorders caused by volatile neural signaling.

31 Mar 2016

Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

A novel mouse model of a highly lethal form of acute myeloid leukemia (AML) offers a new tool for scientists working to better understand this disease and research new therapeutic targets.

31 Mar 2016

LMU-led researchers define previously unknown signaling pathway that triggers inflammation

Using a combination of newly developed methods, researchers led by Ludwig-Maximilians-Universitaet (LMU) in Munich immunologist Veit Hornung have defined a previously unknown pathway that triggers inflammation.

31 Mar 2016

Scientists identify RingoA protein as key regulator of meiosis

Published today in Nature Communications, a study by scientists at the Institute for Research in Biomedicine headed by ICREA researcher Angel R. Nebreda has reported that the protein RingoA is a key regulator of meiosis--the cell division process that gives rise to ovules and sperm for sexual reproduction in mammals.

31 Mar 2016

New Rutgers study links protein that helps fight infection to heart and liver disease

A protein that should help fight infection and keep us healthy may be targeted for treating devastating illnesses like heart and liver disease, according to a new Rutgers study.

31 Mar 2016

University of Guelph professor uncovers secret to staying strong in old age

A University of Guelph professor has uncovered the "secret" to staying strong as we age - superb fitness.

31 Mar 2016

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Key opinions leaders in the field of haematopoetic stem cell transplantation (HSCT) will address the role of Cyclophosphamide, an anti-cancer chemotherapy drug, during the 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) that will welcome more than 4,500 delegates in the host city of Valencia, Spain from the 3rd to the 6th of April 2016.

31 Mar 2016

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

While childhood cancer is rare (adult malignancies after 20 years are 20-30 times more common in general) it remains a major cause of death by disease in children. 15,700 children are diagnosed with cancer each year in the USA.

31 Mar 2016

Fecal transplants transfer bacterial viruses that appear to be harmless to humans

Communities of viruses can be transferred during fecal transplants, according to a study published this week in mBio, an online open-access journal of the American Society for Microbiology. Fortunately for patients who use this procedure, the viruses found to be transmitted in this study appear to be harmless to humans.

30 Mar 2016

Researchers to discuss on innovative cellular therapies during EBMT meeting

Cellular Therapy is an emerging medical science that is today facing a unique developmental phase, well documented by the outstanding and growing numbers of clinical trials.

30 Mar 2016

Researchers uncover new clue that may help fight AML

A study led by researchers from the Cancer Science Institute of Singapore at the National University of Singapore has uncovered a new clue that may help fight acute myeloid leukaemia (AML), the most common form of cancer of the blood and bone marrow, and an aggressive type of cancer. The findings open a new door to treating the disease more effectively.

30 Mar 2016

New device can deliver diagnosis to patient in 30 minutes

When a person contracts a disease, it takes time to diagnose the symptoms. Cell culturing, immunoassay and a nucleic-acid based diagnostic cycle all take several days, if not a week to determine the results. Not only do sick patients suffer during this time period, the wait can also lead to unnecessary disease spreading and perhaps avoidable antibiotic use.

30 Mar 2016

New tool interprets whole-exome tumor sequencing data for better cancer therapies

A University of Colorado Cancer study published today in the Journal of the American Medical Informatics Association describes a new tool that interprets the raw data of whole exome tumor sequencing and then matches the cancer's unique genetics to FDA-approved targeted treatments.

30 Mar 2016

Researchers develop new technique to study blood vessel inflammation

Nanotechnology has led to better diagnostic techniques and more effective treatments for a variety of illnesses. Tiny devices measuring between 1 and 100 micrometers--one micrometer is equal to one millionth of a meter--enable scientists to observe cell activity and deliver drugs to individual cells--a breakthrough that is on the verge of revolutionizing precision medicine for treatment of diseases such as cancer.

30 Mar 2016

Research describes first new mouse model for Zika infection in decades

Efforts to combat the rapid spread of Zika virus got a boost this week as researchers at the University of Texas Medical Branch, Galveston (UTMB) announced the first peer-reviewed publication of a mouse model for Zika infection reported in decades.

30 Mar 2016

Cell News and Research

Aging reduces axonal regeneration after spinal cord injury

Tumor suppressor p53 gene twice as likely to be defective in autistic children

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

Commonly used fungicides could cause gene expression changes in brain cells

Remotely tracking patients' eye gaze could help identify children with ASD

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Scientists develop mouse model to gain new insights into genetic mechanisms underlying AML

LMU-led researchers define previously unknown signaling pathway that triggers inflammation

Scientists identify RingoA protein as key regulator of meiosis

New Rutgers study links protein that helps fight infection to heart and liver disease

University of Guelph professor uncovers secret to staying strong in old age

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

Fecal transplants transfer bacterial viruses that appear to be harmless to humans

Researchers to discuss on innovative cellular therapies during EBMT meeting

Researchers uncover new clue that may help fight AML

New device can deliver diagnosis to patient in 30 minutes

New tool interprets whole-exome tumor sequencing data for better cancer therapies

Researchers develop new technique to study blood vessel inflammation

Research describes first new mouse model for Zika infection in decades

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