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Imaging technology reveals the creation and elimination of synapses in the brains of live mice

A University of Minnesota Twin Cities researcher is part of an international team that has used imaging technology to show, for the first time, the creation and elimination of synapses between neurons in the brains of live mice.

12 Jan 2023

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

One of the most important classes of human enzymes are protein kinases - signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism.

12 Jan 2023

The 2022 U.S. RSV surge consisted of a variety of pre-existing viruses

In a recent study posted to the medRxiv* preprint server, researchers investigated whether the upsurge in respiratory syncytial virus (RSV) infections during the autumn season of 2022 occurred due to the emergence of a novel, highly transmissible RSV strain or whether multiple pre-existing RSV strains were responsible for the increase in RSV case counts during the period.

12 Jan 2023

Brain structures could predict an person's predisposition to accidental awareness under anesthesia

Brain structures which could predict an individual's predisposition to accidental awareness under anesthetic have been identified for the first time by neuroscientists in Trinity College Dublin.

12 Jan 2023

American Cancer Society's annual report on cancer facts and trends released

Today, the American Cancer Society released Cancer Statistics, 2023, the organization's annual report on cancer facts and trends. According to the report, overall cancer mortality has dropped 33% since 1991, averting an estimated 3.8 million cancer deaths.

12 Jan 2023

New technique could overcome the delivery hurdles faced by promising mRNA therapies

A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs).

12 Jan 2023

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Rats and mice have been the backbone of biomedical research for decades - including research to understand cancer and pioneer new treatments.

12 Jan 2023

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.

12 Jan 2023

LJI scientists uncover how OGT enzyme keeps cells healthy

Researchers at La Jolla Institute for Immunology have at last uncovered how an enzyme called O-GlcNAc transferase (OGT) keeps cells healthy.

12 Jan 2023

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines - the so-called gut microbiome - have far-reaching effects on how our bodies function.

12 Jan 2023

New insights into deadly fungal invasion in people with compromised immune systems

Fungi such as Aspergillus are so common in our surroundings that we breathe in hundreds to thousands of spores every day.

12 Jan 2023

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers.

12 Jan 2023

Machine learning-based behavioral intervention can improve end-of-life cancer care

Electronic nudges delivered to health care clinicians based on a machine learning algorithm that predicts mortality risk quadrupled rates of conversations with patients about their end-of-life care preferences, according to the long-term results of a randomized clinical trial published by Penn Medicine investigators in JAMA Oncology today.

12 Jan 2023

Unique mass spectrometry-based approach to study specific changes in DNA after replication

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology.

12 Jan 2023

Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a substantial risk factor for dementia in community-dwelling (noninstitutionalized) older adults, and identified technology as an effective way to intervene.

12 Jan 2023

Study reveals how new cells join existing tissues by reading mechanical information

Integration is not only a problem of social significance among humans, but also an issue for the cells that form us as humans.

12 Jan 2023

Reducing the use of wood- and charcoal-burning stoves could save half a million lives in Africa

Half a million lives could be saved each year in sub-Saharan Africa by taking action to reduce reliance on traditional wood- and charcoal-burning stoves, a new study shows.

12 Jan 2023

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

The Alzheimer's Drug Discovery Foundation and Harrington Discovery Institute at University Hospitals in Cleveland have granted an ADDF-Harrington Scholar Award to Christiane Wrann, PhD, DVM, Associate Professor in Medicine at the Cardiovascular Research Center and the McCance Center for Brain Health at Massachusetts General Hospital and the Harvard Medical School in Boston.

12 Jan 2023

University adopts INTEGRA pipettes for prestigious international competition

Students of Technische Universität Braunschweig, Germany, used INTEGRA Biosciences’ VIAFLO electronic pipettes and EVOLVE manual pipettes to perform sample transfers and dilutions as part of their project for the 2022 iGEM competition.

From INTEGRA Biosciences 12 Jan 2023

Mediterranean diet reduces dietary inflammation scores after six months

A new study looked at the effects of replacing the habitual diet with the Mediterranean diet for six months in older Australians.

12 Jan 2023

Research News and Research

Imaging technology reveals the creation and elimination of synapses in the brains of live mice

Comprehensive atlas of protein kinases could help scientists decipher many cellular signaling pathways

The 2022 U.S. RSV surge consisted of a variety of pre-existing viruses

Brain structures could predict an person's predisposition to accidental awareness under anesthesia

American Cancer Society's annual report on cancer facts and trends released

New technique could overcome the delivery hurdles faced by promising mRNA therapies

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

LJI scientists uncover how OGT enzyme keeps cells healthy

Reshaping the gut microbiome could be a possible way to prevent or treat neurodegeneration

New insights into deadly fungal invasion in people with compromised immune systems

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

Machine learning-based behavioral intervention can improve end-of-life cancer care

Unique mass spectrometry-based approach to study specific changes in DNA after replication

Social isolation is a risk factor for dementia in community-dwelling older adults, studies show

Study reveals how new cells join existing tissues by reading mechanical information

Reducing the use of wood- and charcoal-burning stoves could save half a million lives in Africa

ADDF-Harrington partnership accelerates the translation of innovative Alzheimer's research into therapies

University adopts INTEGRA pipettes for prestigious international competition

Mediterranean diet reduces dietary inflammation scores after six months

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