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CAR T-cell therapy enters into Phase I clinical trial

Cancer fighting chimeric antigen receptor (CAR) T cells, developed in the Sentman laboratory of Dartmouth's Norris Cotton Cancer Center, are taking the next step into a Phase I clinical trial beginning early in 2015.

15 Jan 2015

People with iron overload disease are more vulnerable to Vibrio vulnificus infections

Every summer, the news reports on a bacterium called Vibrio vulnificus found in warm saltwater that causes people to get sick, or die, after they eat raw tainted shellfish or when an open wound comes in contact with seawater.

15 Jan 2015

Platelet transfusion treatment increases death in people with certain rare blood cell disorders

People hospitalized with certain rare blood cell disorders frequently receive a treatment that is associated with a two- to fivefold increase in death, according to a new study that reviewed hospital records nationwide. The study authors recommend that for these rare disorders, doctors should administer the treatment, a platelet transfusion, only in exceptional circumstances.

14 Jan 2015

Weightlessness in space causes blood shift in astronauts

In a study published today in The Journal of Physiology, researchers found that in space, the shift of blood and fluid from the lower to the upper body caused by weightlessness is much higher and the blood pressure much lower than previously thought.

14 Jan 2015

Leading cardiac specialists propose new guidelines for donor heart allocation

A group of leading cardiac specialists has proposed new guidelines for the allocation of donor hearts to patients awaiting transplant. The changes are aimed at improving the organ distribution process to increase the survival rate of patients awaiting transplant and posttransplant.

14 Jan 2015

Universal vaccine against flu may be on the horizon, say researchers

The fact that this year's flu shot is not a good match against this year's influenza strain is well known, and has happened before.

14 Jan 2015

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive licensing deal with PharmAbcine Inc. for the development, manufacturing and marketing of DIG-KT, a bi-specific monoclonal antibody ("mAb") targeting both VEGFR2/KDR and Tie-2 pathways for cancer in the territory of Greater China (including mainland China, Taiwan, Hong Kong and Macau) and Korea.

14 Jan 2015

New article discusses role of cytokines in breast cancer development, progression

Emerging data on the role of inflammation and the immune system in the development, growth, and spread of breast tumors have focused increased attention on the role cytokines such as interleukin and transforming growth factor-β play in breast cancer initiation, protection, and metastasis.

14 Jan 2015

Ascendis Pharma initiates TransCon Treprostinil Phase 1 study in healthy volunteers

Ascendis Pharma A/S, a clinical stage biotechnology company that applies its innovative TransCon technology to address significant unmet medical needs, today announced that it has initiated a Phase 1 single ascending dose study of TransCon Treprostinil in healthy volunteers.

14 Jan 2015

High vitamin D levels boost survival for metastatic colorectal cancer patients

According to a new study led by researchers at Dana-Farber Cancer Institute, clinical trial patients with metastatic colorectal cancer who had high levels of vitamin D in their bloodstream prior to treatment with chemotherapy and targeted drugs, survived longer, on average, than patients with lower levels of the vitamin.

14 Jan 2015

Research findings may lead to new treatment for hypothyroidism

An international research team led by physician-scientists at Rush University Medical Center have gained new insights into hypothyroidism - a condition affecting about 10 million people in the U.S. - that may lead to new treatment protocols for the disease, particularly among the approximately 15 percent of patients for whom standard treatments are less effective.

14 Jan 2015

Bayshore Community Hospital releases new Multi-specialty Interventional Suite

Bayshore Community Hospital recently unveiled its new Multi-specialty Interventional Suite, outfitted with advanced technology capable of performing complex minimally invasive cardiovascular, endovascular, and interventional radiology procedures.

14 Jan 2015

Mayo Clinic expert explains difference between severe sepsis and septic shock

Sepsis can be a dangerous complication of almost any type of infection, including influenza, pneumonia and food poisoning; urinary tract infections; bloodstream infections from wounds; and abdominal infections.

14 Jan 2015

Intrexon and ZIOPHARM Oncology sign exclusive licensing agreement with MD Anderson

Intrexon Corporation, a leader in synthetic biology and its oncology partner, ZIOPHARM Oncology, today announced a broad exclusive licensing agreement with The University of Texas MD Anderson Cancer Center, including an exclusive sublicensing agreement through MD Anderson for intellectual property developed at the University of Minnesota for the development of non-viral adoptive cellular cancer immunotherapies.

14 Jan 2015

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

UCLA transplantation researchers have developed a novel method that more accurately calculates the risk of disease recurrence in liver cancer patients who have undergone a liver transplant, providing a new tool to help physicians make treatment and surveillance decisions.

14 Jan 2015

Duke researchers grow contracting human skeletal muscle in lab

In a laboratory first, Duke researchers have grown human skeletal muscle that contracts and responds just like native tissue to external stimuli such as electrical pulses, biochemical signals and pharmaceuticals.

13 Jan 2015

Study: Community-wide CVD prevention programs help reduce hospitalizations, death rates

In a rural Maine county, sustained, community-wide programs targeting cardiovascular risk factors and behavior changes were associated with reductions in hospitalization and death rates over a 40-year period (1970-2010) compared with the rest of the state. Substantial improvements were seen in control of hypertension and cholesterol, and smoking cessation, according to a study in the January 13 issue of JAMA.

13 Jan 2015

Obstetric care during Ebola epidemic are deeply challenging

Obstetric interventions during an Ebola epidemic are deeply challenging say two new commentaries published today (14 January) in BJOG: An International Journal of Obstetrics and Gynaecology (BJOG).

13 Jan 2015

Review shows that fish compound can help combat cardiovascular disease

A major international review of a peptide originally found in fish that could be used in the battle against cardiovascular disease has been published.

13 Jan 2015

Valorem Surgical reports FDA approval and first utilization of MaxiMIS Spinal Fixation System

Valorem Surgical, an early stage medical device company with a platform on surgically treating spinal pathologies through a minimally invasive (MIS) approach, today announced that the Company has received FDA clearance and its first case utilizing its minimally invasive MaxiMIS Spinal Fixation System, performed by board-certified, neurosurgeon, Dr. Jae Lim in Reston, VA.

13 Jan 2015

Blood News and Research

CAR T-cell therapy enters into Phase I clinical trial

People with iron overload disease are more vulnerable to Vibrio vulnificus infections

Platelet transfusion treatment increases death in people with certain rare blood cell disorders

Weightlessness in space causes blood shift in astronauts

Leading cardiac specialists propose new guidelines for donor heart allocation

Universal vaccine against flu may be on the horizon, say researchers

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

New article discusses role of cytokines in breast cancer development, progression

Ascendis Pharma initiates TransCon Treprostinil Phase 1 study in healthy volunteers

High vitamin D levels boost survival for metastatic colorectal cancer patients

Research findings may lead to new treatment for hypothyroidism

Bayshore Community Hospital releases new Multi-specialty Interventional Suite

Mayo Clinic expert explains difference between severe sepsis and septic shock

Intrexon and ZIOPHARM Oncology sign exclusive licensing agreement with MD Anderson

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

Duke researchers grow contracting human skeletal muscle in lab

Study: Community-wide CVD prevention programs help reduce hospitalizations, death rates

Obstetric care during Ebola epidemic are deeply challenging

Review shows that fish compound can help combat cardiovascular disease

Valorem Surgical reports FDA approval and first utilization of MaxiMIS Spinal Fixation System

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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