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U-M researchers identify how amlexanox drug improves metabolism of sugar

Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver.

13 Jan 2015

How quickly smokers metabolise nicotine may point to best quitting method

The success of different smoking cessation treatments could be predicted by how quickly smokers break down (metabolise) nicotine in their bodies, according to new research published in The Lancet Respiratory Medicine journal.

13 Jan 2015

CML mouse model reveals previously unreported facets of disease

A humanised murine model of chronic phase chronic myeloid leukaemia, developed by a Swedish research team, provides insight into previously unexplored characteristics of the disease.

12 Jan 2015

Blast phase characteristics differ in TKI-, non-TKI–treated CML patients

Features of the blast phase, such as blast cell morphology and accompanying cytogenetic changes, vary between chronic myeloid leukaemia patients who received tyrosine kinase inhibitor therapy and those treated in the pre-TKI era, research shows.

12 Jan 2015

Tandem Diabetes Care receives FDA clearance to market t:flex Insulin Pump

Tandem Diabetes Care, Inc., a medical device company and manufacturer of the t:slim Insulin Pump, today announced that the U.S. Food and Drug Administration has granted the Company clearance to market the t:flex Insulin Pump. At 480 units, the insulin reservoir of the t:flex Pump has the largest capacity currently available in the United States.

12 Jan 2015

New GP Surgery opens in the heart of Wimbledon

The GP Surgery has newly opened in the heart of Wimbledon in response to patient concerns about NHS GP inaccessibility. With increased strain on GP services over the winter period waiting times for a routine GP appointment have increased, with a resulting increased burden on urgent care, A&E and out-of-hours GP services.

12 Jan 2015

QIAGEN's circulating tumor DNA test CE-IVD marked to assess genomic mutation NSCLC patients

QIAGEN announced today the CE-IVD marking of its novel liquid biopsy-based companion diagnostic that analyzes circulating nucleic acids obtained from blood samples to assess an important genomic mutation in patients with non-small cell lung cancer (NSCLC), the most common form of this cancer.

From QIAGEN Manchester Limited 12 Jan 2015

Research findings may lead to new therapeutic target for AML treatment

A study by the Cancer Science Institute of Singapore at the National University of Singapore has found new interactions between two molecules involved in acute myeloid leukaemia (AML), STAT3 and PRL-3, which may offer a new therapeutic target for cancer treatment.

12 Jan 2015

Kidney failure predictors in adolescents: an interview with Dr. Per-Ola Sundin

Diabetes, hypertension and other cardiovascular diseases as well as obesity are some of the markers of risk for kidney failure that we are aware of in adulthood. Markers of risk prior to adulthood for subsequent chronic kidney disease resulting in kidney failure are less well described.

11 Jan 2015

New UCLA study sheds light on why some people develop PTSD

Why do some people develop post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA discovery may shed light on the answer.

11 Jan 2015

Personal gender identity of every human being is reflected in the structure of brain networks

Our sense of belonging to the male or female gender is an inherent component of the human identity perception. As a general rule, gender identity and physical sex coincide. If this is not the case, one refers to trans-identity or transsexuality. In a current study, brain researcher Georg S. Kanz of the University Clinic for Psychiatry and Psychotherapy of the MedUni Vienna was able to demonstrate that the very personal gender identity of every human being is reflected and verifiable in the cross-links between brain regions.

9 Jan 2015

Daiichi Sankyo receives FDA approval for SAVAYSA (edoxaban) Tablets

Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) today announced that the U.S. Food and Drug Administration has approved SAVAYSA (edoxaban) Tablets, an oral, once-daily selective factor Xa-inhibitor, to reduce the risk of stroke and systemic embolism (SE) in patients with non-valvular atrial fibrillation (NVAF).

8 Jan 2015

Exposure to nanoparticles can play major role in development of cardiovascular diseases

Nanoparticles, extremely tiny particles measured in billionths of a meter, are increasingly everywhere, and especially in biomedical products. Their toxicity has been researched in general terms, but now a team of Israeli scientists has for the first time found that exposure nanoparticles (NPs) of silicon dioxide (SiO2) can play a major role in the development of cardiovascular diseases when the NP cross tissue and cellular barriers and also find their way into the circulatory system.

8 Jan 2015

One cup of blueberries per day could help reduce blood pressure, arterial stiffness

Just one cup of blueberries per day could be the key to reducing blood pressure and arterial stiffness, both of which are associated with cardiovascular disease.

8 Jan 2015

CytRx reports positive interim results from aldoxorubicin Phase 2 trial for HIV-related Kaposi's Sarcoma

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced positive interim results from its ongoing Phase 2 clinical trial evaluating the safety and efficacy of aldoxorubicin for the treatment of Kaposi's Sarcoma (KS) in HIV-infected patients.

8 Jan 2015

VolitionRx's NuQ blood-based diagnostic platform demonstrates promising results in clinical study

VolitionRx Limited, a life sciences company focused on developing diagnostic tests for cancer and other conditions, today announced that it has completed a blinded clinical study demonstrating that its NuQ® blood-based diagnostic platform is able to accurately detect 84% of early, surgically-treatable pancreatic cancers at high 92% specificity.

8 Jan 2015

EMA recommends orphan designation to Magnus Growth's novel therapy for placental insufficiency

Magnus Life Science today announces that the European Medicines Agency's Committee for Orphan Medicinal Products has reached a positive decision on recommending orphan designation to Magnus Growth's novel therapy to treat placental insufficiency.

8 Jan 2015

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Enzymes linked to diabetes and obesity appear to play key roles in arthritis and leukemia, potentially opening up new avenues for treating these diverse diseases, according to new research at Washington University School of Medicine in St. Louis.

8 Jan 2015

Johns Hopkins-led study offers strategy to eradicate HIV

Luring dormant HIV out of hiding and destroying its last cure-defying holdouts has become the holy grail of HIV eradication, but several recent attempts to do so have failed. Now the findings of a Johns Hopkins-led study reveal why that is and offer a strategy that could form a blueprint for a therapeutic vaccine to eradicate lingering virus from the body.

8 Jan 2015

American Migraine Foundation plans to create Migraine Patient Registry and Biorepository

Migraine affects 36 million Americans, can have a major impact on patients' quality of life, and even on their relationships. The World Health Organization estimates that migraine is the third most prevalent medical disorder in the world, the 4th most disabling among women and the 7th most disabling overall.

8 Jan 2015

Blood News and Research

U-M researchers identify how amlexanox drug improves metabolism of sugar

How quickly smokers metabolise nicotine may point to best quitting method

CML mouse model reveals previously unreported facets of disease

Blast phase characteristics differ in TKI-, non-TKI–treated CML patients

Tandem Diabetes Care receives FDA clearance to market t:flex Insulin Pump

New GP Surgery opens in the heart of Wimbledon

QIAGEN's circulating tumor DNA test CE-IVD marked to assess genomic mutation NSCLC patients

Research findings may lead to new therapeutic target for AML treatment

Kidney failure predictors in adolescents: an interview with Dr. Per-Ola Sundin

New UCLA study sheds light on why some people develop PTSD

Personal gender identity of every human being is reflected in the structure of brain networks

Daiichi Sankyo receives FDA approval for SAVAYSA (edoxaban) Tablets

Exposure to nanoparticles can play major role in development of cardiovascular diseases

One cup of blueberries per day could help reduce blood pressure, arterial stiffness

CytRx reports positive interim results from aldoxorubicin Phase 2 trial for HIV-related Kaposi's Sarcoma

VolitionRx's NuQ blood-based diagnostic platform demonstrates promising results in clinical study

EMA recommends orphan designation to Magnus Growth's novel therapy for placental insufficiency

Enzymes linked to diabetes, obesity play major roles in arthritis and leukemia

Johns Hopkins-led study offers strategy to eradicate HIV

American Migraine Foundation plans to create Migraine Patient Registry and Biorepository

Industry Focus eBook - Cell biology (5th edition) eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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