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Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

A new study aimed to analyze whether the order of immunization of vaccine types impacted the efficacy of a heterologous prime-boost vaccination strategy.

6 Jan 2023

New research on DNA-repair enzyme could help enhance cancer drug development

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, took a close look at one of ways cells repair broken strands of DNA and discovered details that could help make a particular enzyme a promising target for precision cancer therapy.

6 Jan 2023

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

A study into the use of an at-home test which uses saliva rather than blood to diagnose adrenal insufficiency, which has been developed by scientists at the University of Sheffield with funding from the National Institute for Health and Care Research, and tested in Sheffield endocrine patients at Sheffield Teaching Hospitals NHS Foundation Trust, is making a difference to the health of patients and could reduce time to diagnosis.

6 Jan 2023

After nearly four decades of decline, stroke mortality risk appears to be increasing again in the U.S.

A Rutgers analysis of U.S. stroke deaths from 1975 to 2019 has found both a dramatic decline and the potential for an important resurgence.

6 Jan 2023

CU researchers discover a new mechanism for slowing cardiac fibrosis

Researchers at the University of Colorado School of Medicine have discovered a new mechanism for slowing scarring of heart tissue - a process known as cardiac fibrosis.

6 Jan 2023

Hair follicle transplants can rejuvenate scars, study finds

In a new study involving three volunteers, skin scars began to behave more like uninjured skin after they were treated with hair follicle transplants.

6 Jan 2023

Vitamin D can help the immune system fight tuberculosis, study says

Most people probably associate tuberculosis with a leaky loft in 20th-century Paris. But as a matter of fact, tuberculosis is not ancient history.

6 Jan 2023

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Newly published research from the University of Cincinnati finds that people with latent tuberculosis infection (LTBI) have more inflammation and could be at a higher risk for cardiovascular disease.

6 Jan 2023

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.

6 Jan 2023

PSMA PET/MRI can successfully determine the risk of prostate cancer recurrence

In men recently diagnosed with intermediate or high-grade prostate cancer, prostate specific membrane antigen (PSMA) PET/MRI can successfully determine whether their cancer is likely to return within two years of a prostatectomy.

6 Jan 2023

Cells live longer when they exchange metabolic products with each other

When cells exchange metabolic products with other cells, they live longer. This new finding comes from a research team at Charité – Universitätsmedizin Berlin, which made the discovery in a study using yeast cells.

6 Jan 2023

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

The most common type of liver cancer, hepatocellular carcinoma (HCC), is already the third leading cause of cancer-related deaths globally - and cases are on the rise, both in the U.S. and worldwide.

6 Jan 2023

Low-cost intervention can make a difference to America's deadly overdose epidemic

There are no simple solutions to America's deadly overdose epidemic, which costs 100,000 lives each year and is erasing gains in life expectancy.

6 Jan 2023

Study finds older knee replacement designs to be just as effective as newer models

Older knee replacement designs are just as effective as newer models - according to new research from the Norfolk and Norwich University Hospital and University of East Anglia.

6 Jan 2023

Hybrid immunity confers increased protection against omicron BA.5 for up to 8 months

Study in the population living in Portugal shows that immunity conferred by infection of people vaccinated against COVID-19 confers up to 8 months of protection against omicron BA.5.

6 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

High affinity antibodies isolated to safely target Claudin 6-positive tumors

Integral Molecular, the industry leader in antibody discovery for membrane proteins, has published the targeting mechanism enabling best-in-class specificity of its Claudin 6 (CLDN6) antibody CTIM-76 being developed for cancer therapy with Context Therapeutics.

6 Jan 2023

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Talking, smiling, eating together – these are all social activities that are inherent to the human experience. But for some head and neck cancer survivors, they are dreaded tasks.

6 Jan 2023

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV."

6 Jan 2023

During in-flight emergencies, Sometimes airlines’ medical kits fall short

In March, a Frontier Airlines flight was headed from Phoenix to Las Vegas when a female passenger stopped breathing. The flight attendant yelled in the cabin for help.

6 Jan 2023

Research News and Research

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

New research on DNA-repair enzyme could help enhance cancer drug development

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

After nearly four decades of decline, stroke mortality risk appears to be increasing again in the U.S.

CU researchers discover a new mechanism for slowing cardiac fibrosis

Hair follicle transplants can rejuvenate scars, study finds

Vitamin D can help the immune system fight tuberculosis, study says

People with latent tuberculosis infection could be at a higher risk for cardiovascular disease

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

PSMA PET/MRI can successfully determine the risk of prostate cancer recurrence

Cells live longer when they exchange metabolic products with each other

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

Low-cost intervention can make a difference to America's deadly overdose epidemic

Study finds older knee replacement designs to be just as effective as newer models

Hybrid immunity confers increased protection against omicron BA.5 for up to 8 months

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

High affinity antibodies isolated to safely target Claudin 6-positive tumors

Brief tele-cognitive behavioral therapy for head and neck cancer survivors with body-image distress shows promising results

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

During in-flight emergencies, Sometimes airlines’ medical kits fall short

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