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Ipsen's elafibranor recommended for use in patients with rare liver disease

Ipsen announced today that the National Institute for Health and Care Excellence (NICE) has recommended elafibranor 80mg tablets for the treatment of PBC in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy in adults unable to tolerate UDCA. This makes elafibranor the first medicine for PBC approved for use on the NHS in nearly a decade.

26 Oct 2024

Evaluating the effectiveness of GAAD for early detection of hepatocellular carcinoma

Early detection of hepatocellular carcinoma (HCC) is crucial for improving survival in patients with chronic hepatitis.

25 Oct 2024

Advanced fibrosis linked to liver complications in biopsy-proven MASLD

Data regarding risk factors and long-term outcomes of U.S. patients with biopsy-proven metabolic dysfunction-associated steatotic liver disease (MASLD) are limited.

25 Oct 2024

Study reveals misuse of scientific evidence by opioid makers

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that makers and marketers of prescription opioid painkillers misused scientific evidence to advance five common and inaccurate claims about the safety and effectiveness of prescription opioids - including that they were not addictive.

25 Oct 2024

New AI tool revolutionizes detection of rare gastrointestinal diseases

Researchers from LMU, TU Berlin, and Charité have developed a new AI tool that uses imaging data to also detect less frequent diseases of the gastrointestinal tract.

25 Oct 2024

Researchers unlock potential of light-controlled cellular activities

Researchers at the Paul Scherrer Institute PSI have succeeded in elucidating the structure of specific photoreceptors.

25 Oct 2024

Low-level arsenic exposure in water linked to increased heart disease risk

Research shows long-term arsenic exposure in drinking water raises ischemic heart disease risk by 42%, emphasizing the need for stricter water safety standards.

25 Oct 2024

Presidential election puts Affordable Care Act back in the bull’s-eye

Health care is suddenly front and center in the final sprint to the presidential election, and the outcome will shape the Affordable Care Act and the coverage it gives to more than 40 million people.

25 Oct 2024

Are back problems influenced by your gut?

Findings suggest gut microbiome dysbiosis may influence lumbar degenerative spondylolisthesis, impacting inflammation and pain management strategies.

25 Oct 2024

New 3D body scan method beats traditional imaging for tracking body fat

Researchers developed a new method using 3D body shapes to predict body composition, offering a more accessible alternative to traditional medical imaging. This approach can accurately track fat mass changes over time.

25 Oct 2024

Understanding climate change effects on end stage kidney disease patients

Climate change is driving more extreme heat and more air pollution from wildfires, each of which put human health at risk.

24 Oct 2024

Electric skin patch offers drug-free solution to bacterial infections

Using a few zaps of electricity to the skin, researchers can stop bacterial infections without using any drugs. For the first time, researchers designed a skin patch that uses imperceptible electric currents to control microbes.

24 Oct 2024

Long-term air pollution exposure linked to increased risk of acute kidney injury and mortality

Prolonged exposure to air pollutants like PM2.5 and nitrogen oxides significantly raises acute kidney injury risk and related mortality, urging policy action.

24 Oct 2024

CDC approves monovalent COVID-19 boosters for adults

Today, CDC's Director Rochelle P. Walensky, M.D., M.P.H., signed a decision memo allowing Novavax monovalent COVID-19 boosters for adults.

24 Oct 2024

Low-carb diet may improve beta-cell function in type 2 diabetes patients

This study shows a carbohydrate-restricted diet boosts β-cell function in type 2 diabetes, offering a sustainable approach to manage the disease effectively.

24 Oct 2024

How your baby’s birth and environment can shape lifelong gut health

Early life factors, like birth mode and green environments, shape infant gut microbiota, with outdoor time becoming crucial in late infancy. Residential greenery impacts diversity only during early infancy.

24 Oct 2024

Study reveals innovative treatment for narcolepsy-related nightmares

A new Northwestern Medicine study has demonstrated a new way to treat narcolepsy-related nightmares.

23 Oct 2024

Immunotherapy may be an effective treatment strategy for heart failure

A new study from Washington University School of Medicine in St. Louis suggests that a type of immunotherapy - similar to that approved by the Food and Drug Administration (FDA) to treat inflammatory conditions such as arthritis - also may be an effective treatment strategy for heart failure.

23 Oct 2024

Groundbreaking findings on TET2 pathway open doors for targeted blood cancer treatments

Approximately 30% of individuals with myeloid malignancy diseases have a mutation in a certain gene called tet methylcytosine dioxygenase 2 (TET2).

23 Oct 2024

Rise in weight-management glucose-lowering drug prescriptions in type 1 diabetes patients

From 2010 to 2023, GLP-1RAs and SGLT2 inhibitors saw rising prescriptions in type 1 diabetes, particularly for patients with obesity and cardiorenal risks.

23 Oct 2024