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Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

A new study from the University of Calgary could change the way researchers understand and treat autoimmune diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis.

22 Feb 2016

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Chemotherapy isn't supposed to make your hair fall out -- it's supposed to kill cancer cells. A new molecular delivery system created at U of T Engineering could help ensure that chemotherapy drugs get to their target while minimizing collateral damage.

22 Feb 2016

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Australian researchers have resolved a mystery about how a promising new class of anti-cancer drugs, called nutlins, work - paving the way for improving the future of cancer treatment.

22 Feb 2016

3-D map of critical protein could lead to new malaria vaccine

A three-dimensional 'map' of a critical protein that malaria parasites use to invade human red blood cells could lead to a vaccine countering the most widespread species of the parasite.

22 Feb 2016

Researchers identify new group of powerful Ebola-fighting antibodies

A research team that included scientists from The Scripps Research Institute has identified a new group of powerful antibodies to fight Ebola virus.

22 Feb 2016

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

Researchers have discovered that eliminating cells thought to aid tumor growth did not slow or halt the growth of cancer tumors. In fact, when the cancer-associated fibroblasts (CAFs), were eliminated after 10 days, the risk of metastasis of the primary tumor to the lungs and bones of mice increased dramatically.

22 Feb 2016

New study focuses on safety of using induced pluripotent stem cells in patients

A new study led by scientists at The Scripps Research Institute and the J. Craig Venter Institute shows that the act of creating pluripotent stem cells for clinical use is unlikely to pass on cancer-causing mutations to patients.

22 Feb 2016

New discoveries provide further evidence for benefits of a good night's sleep

Why does sleeping on it help? This is the question tackled by new research at the University of Bristol, which reveals how brain activity during sleep sorts through the huge number of experiences we encounter every day, filing only the important information in memory.

22 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

Positive findings from two clinical trials have been published for the immunomodulatory agent lenalidomide in patients with heavily pretreated mantle cell lymphoma, and in adults with T-cell leukaemia-lymphoma or peripheral T-cell lymphoma.

19 Feb 2016

Kellogg investigators develop new nanotechnology that has potential to kill tumor cells in the eye

Researchers at the University of Michigan Kellogg Eye Center have developed a new nanoparticle that uses a tumor cell's protective mechanism against itself -- short-circuiting tumor cell metabolism and killing tumor cells.

19 Feb 2016

KU Leuven scientists improve survival of implanted bone cells

To treat a complicated, non-healing bone defect, surgeons often use an implant with living cells to promote bone repair, but the implanted cells have a small chance of surviving because they are not prepared for a lack of oxygen and nutrients at the fracture site.

19 Feb 2016

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Novartis announced today that the United States Food and Drug Administration has granted Breakthrough Therapy designation to PKC412 (midostaurin). PKC412 (midostaurin) is an investigational treatment for adults with newly-diagnosed AML who are FLT3 mutation-positive, as detected by an FDA-approved test, and who are eligible to receive standard induction and consolidation chemotherapy.

19 Feb 2016

Researchers examine molecular profile of HPV-positive oropharyngeal squamous cell carcinoma

Throat cancer patients exposed to both human papillomavirus (HPV) and tobacco smoke demonstrate a pattern of mutations along several key cancer genes, according to research presented today at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Post-treatment imaging can help detect recurrences of HPV-positive oropharyngeal cancer

For patients treated with definitive radiation therapy (RT) for oropharyngeal cancer caused by human papillomavirus (HPV), the majority of recurrences can be detected by post-treatment imaging at three months and physical exams during the six months following treatment, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Virginia Tech scientist finds way to potentially track and stop viruses

Viruses are molecular thieves that take from their hosts under the cloak of darkness. But now a Virginia Tech scientist has found a way to not only track viral hijackers, but also potentially stop them from replicating.

19 Feb 2016

SBP study opens door for new approaches to treat muscle diseases

Scientists at Sanford Burnham Prebys Medical Discovery Institute have found a key to enhancing repair of damaged muscle. In work published today in Cell Reports, scientists describe why fetal muscle stem cells (MuSCs) are better at regenerating muscle compared to adult MuSCs.

19 Feb 2016

Induction chemotherapy fails to improve survival in head and neck cancer patients

Head and neck cancer patients who receive chemotherapy prior to radiation therapy (induction chemotherapy or IC) rather than the standard treatment that combines chemotherapy with radiation (chemoradiation or CRT) show no survival benefit and are less likely to receive a full course of radiation, according to research from the University of Colorado Cancer Center presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Uninsured and Medicaid patients have higher overall and cancer-specific mortality rates

Compared to patients with non-Medicaid insurance, uninsured patients and patients with Medicaid are more likely to present with advanced stages of head and neck cancer and have higher overall and cancer-specific mortality rates, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Stem cell research reveals how Parkinson’s spreads from cell to cell

Stem cell research published today offers up new clues as to how Parkinson’s spreads from cell to cell, a process which has evaded researchers for decades.

19 Feb 2016

Cell News and Research

Calgary researchers develop new class of nanomedicines to treat autoimmune diseases

New molecular delivery system could help ensure delivery of chemotherapy drugs into tumours

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

3-D map of critical protein could lead to new malaria vaccine

Researchers identify new group of powerful Ebola-fighting antibodies

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

New study focuses on safety of using induced pluripotent stem cells in patients

New discoveries provide further evidence for benefits of a good night's sleep

Researchers identify common molecular alteration in glioblastoma

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

Kellogg investigators develop new nanotechnology that has potential to kill tumor cells in the eye

KU Leuven scientists improve survival of implanted bone cells

Novartis receives FDA Breakthrough Therapy designation for PKC412 (midostaurin)

Researchers examine molecular profile of HPV-positive oropharyngeal squamous cell carcinoma

Post-treatment imaging can help detect recurrences of HPV-positive oropharyngeal cancer

Virginia Tech scientist finds way to potentially track and stop viruses

SBP study opens door for new approaches to treat muscle diseases

Induction chemotherapy fails to improve survival in head and neck cancer patients

Uninsured and Medicaid patients have higher overall and cancer-specific mortality rates

Stem cell research reveals how Parkinson’s spreads from cell to cell

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