Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

UCSF researchers find that people divided on cardiovascular benefits of alcohol consumption

In one of the first published studies using data from the Health eHeart Study, UCSF researchers have found that people are divided on the cardiovascular benefits of alcohol consumption. And, those who do perceive alcohol as "heart healthy" drink substantially more than their counterparts.

17 Jun 2015

FDA grants Fast Track designation to Juventas' JVS-100 drug candidate and allows Phase 2b clinical trial

Juventas Therapeutics, Inc., a clinical-stage biotechnology company developing novel non-viral gene therapies that activate natural processes to repair the body, today announced that its product candidate, JVS-100, received Fast Track designation from the U.S. Food and Drug Administration for the treatment of advanced ischemic chronic heart failure.

16 Jun 2015

Experimental drug improves failing heart's function

An experimental drug improves the ability of heart muscle cells damaged by heart failure to pump blood, according to the results of a study led by Icahn School of Medicine at Mount Sinai researchers and published online today in Nature Communications.

14 Jun 2015

Triciribine drug may reverse progression of pulmonary fibrosis and pulmonary hypertension

Researchers at the University of Georgia have discovered that the drug triciribine may reverse or halt the progression of pulmonary fibrosis and pulmonary hypertension, two respiratory diseases that are almost invariably fatal.

13 Jun 2015

Mount Sinai cardiologists implant microchip sensors to better monitor patients with heart failure

Cardiologists at The Mount Sinai Hospital have begun implanting tiny, state-of-the-art microchip sensors in patients with advanced heart failure to better monitor symptoms and reduce their chances of returning to the hospital.

12 Jun 2015

Lung cancer patients with comorbid conditions face higher risk of death

Lung cancer patients with comorbid conditions such as chronic obstructive pulmonary disease, diabetes, or congestive heart failure had a higher risk of death than lung cancer patients without comorbid conditions, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

12 Jun 2015

Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Amgen today announced that the Company will discuss the data supporting the Repatha (evolocumab) Biologics License Application (BLA) for the treatment of high cholesterol with the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC).

10 Jun 2015

Switching from Remicade to Inflectra benefits patients with rheumatic diseases

Hospira, Inc., a global leader in biosimilars, today announced the results of an independent clinical study, showing patients with rheumatic diseases experienced comparable clinical effectiveness and safety after switching from Remicade™ to Inflectra.

10 Jun 2015

Rapid cooling procedures prior to catheterization reduce extent of myocardial infarction

After an acute myocardial infarction, patients treated with rapid lowering of body temperature by combined cold saline infusion and endovascular cooling had less heart muscle damage and reduced incidence of heart failure. Therapeutic hypothermia was especially protective against heart muscle damage in patients with a large area of myocardium at risk according to an analysis of two clinical trials published in Therapeutic Hypothermia and Temperature Management, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

10 Jun 2015

Images revealing structure of heart cell may provide clues to reducing heart attack damage

Newly released images revealing the 'bicycle spoke' structure of a heart cell may hold key clues to reducing damage from a heart attack.

10 Jun 2015

Stemedica receives FDA's IND approval for itMSC Phase IIa clinical trial to treat Alzheimer's disease

Stemedica Cell Technologies, Inc. received the FDA's investigational new drug (IND) approval for a United States-based, Phase IIa clinical study using its allogeneic stem-cell therapy to treat subjects with mild to moderate dementia due to Alzheimer's disease (AD), the sixth leading cause of death in the United States.

9 Jun 2015

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

A clinical trial of the glucose-control drug sitagliptin among patients with type 2 diabetes and established cardiovascular disease has found it did not raise the risk of major adverse cardiovascular events.

9 Jun 2015

Scientists develop computational method to study link between birth month and disease risk

Columbia University scientists have developed a computational method to investigate the relationship between birth month and disease risk.

9 Jun 2015

Sanofi announces results from Phase IIIb ELIXA study of Lyxumia in adults with diabetes and high CV risk

Sanofi announced today the presentation of full results of the Phase IIIb ELIXA study, which was designed to assess the cardiovascular (CV) safety of Lyxumia (lixisenatide) in adults with type 2 diabetes and high CV risk.

8 Jun 2015

Physicians at UH Case Medical Center implant revolutionary device to treat right ventricular heart disease

University Hospitals Case Medical Center physicians in the Harrington Heart & Vascular Institute were the first in the state of Ohio to implant a revolutionary device to treat right ventricular heart disease.

5 Jun 2015

Withholding ARBs for longer than two days after surgery significantly increases risk of postoperative death

Withholding angiotensin receptor blockers (ARBs) for longer than two days after surgery is associated with a significantly increased risk of postoperative death, according to a study of more than 30,000 patients in the VA health care system by researchers at UC San Francisco and the San Francisco VA Medical Center.

5 Jun 2015

Cytokinetics, The ALS Association expand partnership to fight against ALS

Cytokinetics, Incorporated and The ALS Association announced an expanded partnership in which the company will provide Gold Level Sponsorship of the National Walks to Defeat ALS as well as Platinum Level Sponsorship for ALS Association Golden West Chapter initiatives.

4 Jun 2015

Cyberonics announces results for fourth quarter and fiscal year 2015

Cyberonics, Inc. today announced results for the fourth quarter and fiscal year ended April 24, 2015.

4 Jun 2015

Keeping blood sugar levels under control can help protect hearts from diabetes-related damage

Day in and day out, for years on end, millions of people with diabetes prick their fingers to test their blood sugar level. And many may wonder if all the careful eating, exercise and medication it takes to keep those levels under control is really worth it.

4 Jun 2015

Expert report highlights urgent action needed to lessen the future impact of Atrial Fibrillation in Europe

Researched and written by RAND Europe, with contributions from a panel of leading European medical, patient group and health economic experts, the Future of Anticoagulation Report explores how decisions made today can change and reshape the landscape of tomorrow...

3 Jun 2015

Heart Failure News and Research

Further Reading

UCSF researchers find that people divided on cardiovascular benefits of alcohol consumption

FDA grants Fast Track designation to Juventas' JVS-100 drug candidate and allows Phase 2b clinical trial

Experimental drug improves failing heart's function

Triciribine drug may reverse progression of pulmonary fibrosis and pulmonary hypertension

Mount Sinai cardiologists implant microchip sensors to better monitor patients with heart failure

Lung cancer patients with comorbid conditions face higher risk of death

Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Switching from Remicade to Inflectra benefits patients with rheumatic diseases

Rapid cooling procedures prior to catheterization reduce extent of myocardial infarction

Images revealing structure of heart cell may provide clues to reducing heart attack damage

Stemedica receives FDA's IND approval for itMSC Phase IIa clinical trial to treat Alzheimer's disease

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

Scientists develop computational method to study link between birth month and disease risk

Sanofi announces results from Phase IIIb ELIXA study of Lyxumia in adults with diabetes and high CV risk

Physicians at UH Case Medical Center implant revolutionary device to treat right ventricular heart disease

Withholding ARBs for longer than two days after surgery significantly increases risk of postoperative death

Cytokinetics, The ALS Association expand partnership to fight against ALS

Cyberonics announces results for fourth quarter and fiscal year 2015

Keeping blood sugar levels under control can help protect hearts from diabetes-related damage

Expert report highlights urgent action needed to lessen the future impact of Atrial Fibrillation in Europe

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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