Analgesia News and Research

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Amphar, ETView Medical to distribute VivaSight airway devices

ETView Medical Ltd. announced today that it has entered into a distribution agreement with Amphar b.v. (Amphar). The agreement enables Amphar to market ETView's VivaSight platform, combining an airway ventilation tube with integrated continuous high resolution airway imaging for patient airway control and lung isolation capability in the Netherlands.

19 Mar 2012

Korean FDA grants pre-market clearance for ETView's VivaSight‐SL airway management solutions

ETView today announced that the Korean Food and Drug Administration ("KFDA") has granted pre-market clearance for VivaSight‐SL. With KFDA clearance, ETView plans to immediately initiate market launch of VivaSight‐SL. ETView also announced a distribution agreement with ChinooMTech Company.

12 Mar 2012

AcelRx initiates ARX-01 Phase 3 study for treatment of post-operative pain

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain, reported dosing of the first patient in a Phase 3 study for ARX-01, the Sufentanil NanoTab PCA System, its novel sublingual patient-controlled analgesia system.

6 Mar 2012

Desflurane may be safer anesthetic option for patients with AD

In a study that will appear in Annals of Neurology and has received early online release, Massachusetts General Hospital (MGH) researchers report that administration of isoflurane impaired the performance of mice on a standard test of learning and memory - a result not seen when another anesthetic, desflurane, was administered.

2 Mar 2012

Methylnaltrexone may restore bowel function in critically ill patients

Opioids are a mainstay of care in the critical care unit, but their use frequently causes constipation which can lead to adverse outcomes including delayed feeding and later discharge from the ICU. Researchers from London, UK, and Chicago, IL, have found that methylnaltrexone (MNTX), a peripheral opioid antagonist, may restore bowel function in critically ill patients.

2 Mar 2012

New NPS information on dextropropoxyphene: recommendations and alternatives

NPS has published information online for prescribers to help them prepare for the TGA’s cancellation of Capadex and Paradex, two of the four medicines available in Australia containing dextropropoxyphene.

1 Mar 2012

'Call to action' on wrong-route injections in anesthesia

Worldwide changes in catheter system design are urgently needed to prevent serious complications caused by accidental injection of drugs into the wrong location, according to a special editoral in the March issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

1 Mar 2012

More than 80% of anesthesiologists have been involved in surgical catastrophes

More than 80 percent of anesthesiologists have been involved in a catastrophic event involving death or injury to a patient during surgery, suggests a survey study in the March issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

1 Mar 2012

ETView Medical enters into patent license agreement for thoracic surgery devices

ETView Medical Ltd. announced today that it has entered into an exclusive license agreement for 2 US patents with James S. Simon, M.D., of Tiburon, California. The licensed patents are U.S. Pat. No. 7,052,456, entitled "Airway products having LEDs", and U.S. Pat. No. 6,189,533, entitled "Endotracheal Intubation Device".

20 Feb 2012

Innocoll completes XaraColl End-of-Phase 2 meeting with FDA

Innocoll, Inc. announced that it has held an End-of-Phase 2 meeting with the FDA to present the results of the Phase 2 clinical studies completed for XaraColl and to discuss the proposed safety and efficacy studies to be conducted in Phase 3. XaraColl is being developed for postoperative analgesia and Innocoll plans to undertake its Phase 3 program in patients undergoing hernia repair.

17 Feb 2012

Erasing neuronal memories may help control persistent pain

For some, the pain is so great that they can't even bear to have clothes touch their skin. For others, it means that every step is a deliberate and agonizing choice. Whether the pain is caused by arthritic joints, an injury to a nerve or a disease like fibromyalgia, research now suggests there are new solutions for those who suffer from chronic pain.

13 Feb 2012

Trevena commences TRV130 Phase I clinical trial for severe post-operative pain

Trevena, Inc., the leader in discovery and development of G-protein coupled receptor (GPCR) biased ligands, announced today the initiation of a Phase I clinical trial of TRV130, a novel candidate designed for the intravenous treatment of moderate-to-severe post-operative pain.

13 Feb 2012

Bupivacaine may effectively manage pain after total knee replacement

Researchers at the Rothman Institute at Jefferson have shown that local anesthesia delivered through a catheter in the joint, intraarticularly, may be more beneficial than traditional opioids such as morphine and Oxycontin for pain management following total knee replacement surgery.

10 Feb 2012

Nuvo launches Synera in the U.S.

Nuvo Research Inc., a specialty pharmaceutical company dedicated to building a portfolio of products for the topical treatment of pain and the development of its immune modulating drug candidate WF10, today announced the U. S. launch of Synera.

3 Feb 2012

General anesthesia may lower recurrence risk in patients with HCC

For patients undergoing a minimally invasive treatment for liver cancer, the risk of recurrent cancer appears lower with general anesthesia compared to regional (epidural) anesthesia, reports a study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

1 Feb 2012

Continuous wound infusion with local anesthetic reduces pain after hip surgery

In patients undergoing hip replacement surgery, using a special wound catheter to infuse local anesthetic directly into the hip joint provides significant and lasting improvements in postoperative pain control, reports a study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

1 Feb 2012

AICAR might protect against heat stress in MH-susceptible individuals

Malignant hyperthermia (MH) is a life-threatening genetic muscle disorder, most commonly triggered in those at risk by certain types of drugs used during anesthesia. Heat stroke, on the other hand, most commonly occurs in individuals in response to physical exertion in hot/humid environments. While their common triggers may differ, the signs associated with MH and heat stroke are remarkably similar - uncontrolled muscle contractions, dangerous increases in body temperature, and muscle breakdown leading to the release of toxins in the blood which may cause cardiac arrhythmias and death. Immediate treatment for these conditions is crucial.

13 Jan 2012

Pacira provides updated timing for commercial launch of EXPAREL

Pacira Pharmaceuticals, Inc. today provided updated timing for its commercial launch of EXPAREL (bupivacaine liposome injectable suspension), a non-opioid analgesic that was approved by the U.S. Food and Drug Administration (FDA) for administration into the surgical site to produce postsurgical analgesia.

9 Jan 2012

IARS celebrates 90 years of support of anesthesia-related research

The International Anesthesia Research Society (IARS), the oldest professional society for anesthesiologists, originally founded as the National Anesthesia Research Society, celebrates 90 years of support of medical research in 2012.

5 Jan 2012

$First study to explore impact of crowding on children with fracture-related pain$

First study to explore impact of crowding on children with fracture-related pain

Crowding in hospital emergency departments has led to a decrease in the timely and effective use of pain medication in children suffering acute long bone fractures, according to a new study by the University of Colorado School of Medicine.

23 Dec 2011