Bone Marrow Transplant News and Research

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ALL induction treatment failure should not be an automatic indication for bone marrow transplant

International study that included St. Jude Children's Research Hospital reports some young acute lymphoblastic leukemia patients who fail induction therapy can achieve high cure rates without bone marrow transplantation.

12 Apr 2012

Proteonomix provides corporate and clinical trial updates

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today provided updates on its progress.

10 Apr 2012

Platelet activating factor plays a crucial role in development of graft-versus-host disease

A new discovery in mice may lead to new treatments that could make bone marrow transplants more likely to succeed and to be significantly less dangerous.

2 Apr 2012

Federal Court refuses to reconsider bone marrow donor payments

According to a federal appeals court it would not reconsider a ruling that allows bone marrow donors to be paid for their donations like blood donors.

29 Mar 2012

New gene transfer technique can treat beta-thalassemia, sickle cell anemia

A team of researchers led by scientists at Weill Cornell Medical College has designed what appears to be a powerful gene therapy strategy that can treat both beta-thalassemia disease and sickle cell anemia. They have also developed a test to predict patient response before treatment.

28 Mar 2012

Routine counseling on fertility preservation needed for young women with cancer

A new study has found that very few young women with cancer take steps to preserve their fertility while undergoing cancer therapy. Also, certain groups of young women are more likely to do so than others. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that efforts are needed to provide counseling on fertility preservation in reproductive-aged women diagnosed with cancer.

26 Mar 2012

CIBMTR report shows higher survival rate for patients treated at RPCI's BMT program

Outcomes for patients treated through the Blood and Marrow Transplant Program at Roswell Park Cancer Institute (RPCI) are among the highest in the nation. For the second consecutive year, a report compiled by the Center for International Blood and Marrow Transplant Research (CIBMTR) shows that the one-year survival rate for transplant patients treated at RPCI was significantly higher than expected, affirming RPCI's position among the elite of U.S. centers performing the procedure.

21 Mar 2012

Paper describes results of BMT in models of Rett Syndrome

A paper published online today in Nature describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe symptoms of the childhood disorder, including abnormal breathing and movement, and significantly extended the lifespan of Rett mouse models.

19 Mar 2012

Combination therapy may improve life span and motor function of infants with Batten disease

Infants with Batten disease, a rare but fatal neurological disorder, appear healthy at birth. But within a few short years, the illness takes a heavy toll, leaving children blind, speechless and paralyzed. Most die by age 5.

16 Mar 2012

Doctors can use genetic profiling to more accurately predict patients with AML

Researchers have identified a set of genetic abnormalities in patients with acute myelogenous leukemia (AML) that doctors can use to more accurately predict patients' prognoses and select treatments that are most likely to benefit them.

15 Mar 2012

Researchers identify molecule that helps decrease acute GVHD severity

Researchers have identified a molecule that helps control the severity of graft-versus-host disease, a life-threatening complication for many leukemia patients who receive a bone-marrow transplant.

12 Mar 2012

Proceeds from Polo Under the Palms in Sarasota to benefit MD Anderson Cancer Center

Polo mallets and palm trees take center stage as Polo Under the Palms returns to Sarasota, Fla., March 24. Proceeds from the second annual competition benefit The University of Texas MD Anderson Cancer Center.

2 Mar 2012

Positive data from Chimerix CMX001 Phase 2 study on CMV disease

Chimerix, Inc., a biotechnology company developing novel antiviral therapeutics, today announced positive results from CMX001 Study 201, a Phase 2 study evaluating CMX001 for the prevention of cytomegalovirus (CMV) disease in hematopoietic stem cell transplant (HCT) recipients.

6 Feb 2012

Positive results from Chimerix CMX001 study for CMV in hematopoietic stem cell transplant recipients

6 Feb 2012

Tennessee Gov. declares February as 'St. Jude Month'

In 1962, St. Jude Children's Research Hospital opened its doors amid an emotionally charged debate regarding how to treat childhood cancer. At that time, few children with the most common form of childhood cancer survived, and many physicians believed treatment was futile. St. Jude physicians and researchers took a radically different approach, and these efforts proved pivotal in changing the way the world treats childhood cancer.

6 Feb 2012

Immune cells from healthy individuals effectively kill cancer cells

Immune cells from healthy individuals can be the new immune cure for cancer. This treatment can kill cancer cells without destroying neighbouring cells. The hope is to eradicate cancer for ever.

3 Feb 2012

Patient enrollment complete in Enlivex Phase I/II clinical trial for autoimmune diseases

Hadasit Bio-Holdings a publicly traded portfolio of biotech companies, all based on intellectual property developed and owned by Hadassah University Hospital, Israel's foremost medical research center, today announced that the recruitment of 13 patients for the Enlivex Phase I/II clinical trial has been completed.

23 Jan 2012

Alpha-1-antitrypsin may reduce effects of GVHD

A natural enzyme derived from human blood plasma showed potential in significantly reducing the effects of graft-vs.-host disease, a common and deadly side effect of lifesaving bone marrow transplants.

18 Jan 2012

Ivera receives new FDA clearance for Curos disinfecting port protector

Ivera Medical Corporation today announced it has received a new FDA 510(k) clearance for its Curos disinfecting port protector which reflects the company's ongoing determination to continuously improve its products to better deliver solutions designed to reduce hospital-acquired catheter related bloodstream infections.

18 Jan 2012

Findings on cell working could lead to test and therapy for kidney failure caused by E. coli

New findings by St. Michael's researchers about the way cells work could lead to a test and therapy for kidney failure caused by E. coli

11 Jan 2012

Bone Marrow Transplant News and Research

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

Proteonomix provides corporate and clinical trial updates

Platelet activating factor plays a crucial role in development of graft-versus-host disease

Federal Court refuses to reconsider bone marrow donor payments

New gene transfer technique can treat beta-thalassemia, sickle cell anemia

Routine counseling on fertility preservation needed for young women with cancer

CIBMTR report shows higher survival rate for patients treated at RPCI's BMT program

Paper describes results of BMT in models of Rett Syndrome

Combination therapy may improve life span and motor function of infants with Batten disease

Doctors can use genetic profiling to more accurately predict patients with AML

Researchers identify molecule that helps decrease acute GVHD severity

Proceeds from Polo Under the Palms in Sarasota to benefit MD Anderson Cancer Center

Positive data from Chimerix CMX001 Phase 2 study on CMV disease

Positive results from Chimerix CMX001 study for CMV in hematopoietic stem cell transplant recipients

Tennessee Gov. declares February as 'St. Jude Month'

Immune cells from healthy individuals effectively kill cancer cells

Patient enrollment complete in Enlivex Phase I/II clinical trial for autoimmune diseases

Alpha-1-antitrypsin may reduce effects of GVHD

Ivera receives new FDA clearance for Curos disinfecting port protector

Findings on cell working could lead to test and therapy for kidney failure caused by E. coli

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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