Mastectomy News and Research

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Mastectomy is surgery to remove the breast (or as much of the breast tissue as possible).

NHS hospitals have scope to make efficiency savings by adopting best practice

NHS hospitals have substantial scope to improve their efficiency by adopting best practice, according to research published today by Professor Andrew Street and colleagues at the Centre for Health Economics (CHE) at the University of York.

14 Jul 2012

Breast cancer patients who undergo breast conserving surgery often have a reoperation

One in five women with breast cancer who opt for breast conserving surgery rather than a mastectomy have a reoperation, according to a national study published on bmj.com today. This information on the risk of reoperation should help women in making the decision about whether to undergo breast conserving surgery or mastectomy.

13 Jul 2012

PGD for breast cancer genes BRCA1/2 is now feasible

Preimplantation genetic diagnosis (PGD) for the breast cancer genes BRCA1/2 is now feasible and established, with good success rates for those treated, according to investigators from the reproduction, oncology and genetics centres of the university hospitals of Maastricht and Brussels.

3 Jul 2012

Variations in microRNA expression within breast tumors can lead to sampling bias

Certain short strands of RNA, known as microRNAs (miRNAs), have been linked to the progression and metastasis of breast cancer and may provide information about prognosis. However, studies of miRNA expression profiles often report conflicting findings. While the potential for using miRNAs in breast cancer diagnosis is promising, scientists report in a new study published online today in The Journal of Molecular Diagnostics that differences in the amount and types of miRNA within breast tumors can be misleading.

15 Jun 2012

Distinct cancer 'signatures' may help predict response to estrogen-lowering therapy

Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer "signatures" that could help predict which women are most likely to benefit from estrogen-lowering therapy, while sparing others from unnecessary treatment.

11 Jun 2012

Preoperative opportunity to control blood glucoses

Patients with diabetes mellitus experience significantly higher rates of surgical and systemic complications, higher mortality and increased length of stay during hospitalization following 11 major elective procedures, according to research presented today at the American Association of Clinical Endocrinologists (AACE) 21st Annual Meeting & Clinical Congress in Philadelphia.

28 May 2012

Blocking Skp2 protein might inhibit glycolysis and treat breast cancer

HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.

28 May 2012

Breast brachytherapy with strut-based applicator effective for early-stage breast cancer

Breast brachytherapy with a strut-based applicator is a well-tolerated and effective treatment for early-stage breast cancer, according to a multi-site study with a median follow-up of four years. The research was presented as a scientific poster at the European Society for Radiology & Oncology (ESTRO) World Congress of Brachytherapy in Barcelona, May 10-12.

14 May 2012

Accelerated partial breast irradiation does not compromise survival

Using a concentrated, highly targeted dose of radiation to the breast has equally good results as irradiating the whole area, with no adverse effects on survival and a much better cosmetic outcome, Hungarian researchers have found.

11 May 2012

Domain Surgical's FMwand successfully used in 100 cases

Domain Surgical, a leading developer of advanced thermal surgical technology, today announced that its novel FMwand Ferromagnetic Surgical System has been used successfully in 100 cases. The FMwand simultaneously cuts and coagulates tissue without passing electrical current into the patient, making it safe to use near delicate tissue structures.

9 May 2012

Breast brachytherapy with strut-based applicator effective for women with DCIS

Breast brachytherapy with a strut-based applicator appears to be an effective treatment for women who have ductal carcinoma in situ (DCIS) of the breast, according to a groundbreaking study presented at the annual meeting of the American Society of Breast Surgeons, held in Phoenix May 2-4.

8 May 2012

Breast cancer in men rarer but more deadly than in women

“Men with breast cancer don't do as well as women with breast cancer, and there are opportunities to improve that,” said study author Dr. Jon Greif, a breast surgeon in San Francisco. “They were less likely to get the standard treatments that women get.” Survival rates for men with breast cancer, overall, are lower than those for women, at least when it is diagnosed in the early stages, Greif found. The cancers differ in other respects too.

8 May 2012

Radiofrequency ablation during breast cancer surgery can provide effective alternative to XRT

Radiofrequency ablation of the lumpectomy site during breast cancer surgery can provide an effective alternative to post-operative external radiation therapy (XRT) and reduce repeat surgeries to achieve clear tumor margins, according to one of the first published long-term studies to examine this new treatment protocol.

5 May 2012

Many women diagnosed with breast cancer report no family history

More than half the women aged 40-49 diagnosed with breast cancer on screening mammography report no family history, a new study shows.

4 May 2012

Misleading information about breast brachytherapy

One of the leading experts on radiation therapy for breast cancer says a new study in JAMA -- about breast cancer treatment - has misleading information and may unnecessarily deter women from getting breast brachytherapy, a safe and effective treatment.

2 May 2012

Accelerated partial breast irradiation therapy increases risk for subsequent mastectomy

Accelerated partial breast irradiation (APBI) brachytherapy, the localized form of radiation therapy growing increasingly popular as a treatment choice for women with early-stage breast cancer, is associated with higher rate of later mastectomy, increased radiation-related toxicities and post-operative complications, compared to traditional whole breast irradiation (WBI), according to researchers from The University of Texas MD Anderson Cancer Center.

2 May 2012

Surgeons not including radiation oncologists early enough in treatment decision-making processes

Surgeons are not always including radiation oncologists early enough in a patient's treatment decision-making process, leaving some patients uninformed of all of their treatment options and potentially leading to more mastectomies over breast-conserving therapy, according to a study in the April issue of the International Journal of Radiation Oncology-Biology-Physics, the official scientific journal of the American Society for Radiation Oncology (ASTRO).

19 Apr 2012

Surgery to remove only the tumor preferable to removing entire kidney

Kidney cancer patients who had only their tumor removed had better survival than patients who had their entire kidney removed, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

18 Apr 2012

Tumor size helps predict survival in node-negative breast cancer patients

Research from investigators at The Cancer Institute of New Jersey (CINJ), UMDNJ-School of Public Health (SPH) and UMDNJ-Robert Wood Johnson Medical School, indicates that tumor size stratified by age, race and hormone receptor status helps predict survival in node-negative breast cancer patients.