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New class of sound wave could lead to revolution in stem cell therapy

Acoustics experts have created a new class of sound wave - the first in more than half a century - in a breakthrough they hope could lead to a revolution in stem cell therapy.

7 Jan 2016

Interpretation of images starts in the retina

Tübingen researchers have shown that image processing in the eye is more extensive than previously thought. They investigated the channels that transmit information from the eye to the brain.

7 Jan 2016

Elsevier's new open access journal features novel method to make cancer clinical trials more effective

The first issue of Elsevier's new open access journal Contemporary Clinical Trials Communications features a new method to make cancer clinical trials more effective, a better way of determining whether a trial was successful and a dashboard that helps patients enroll in trials.

7 Jan 2016

DNA damage may lead to mutation and changes in cell

A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly damaged by things from the outside environment, like sunlight, cigarette smoke and radiation. However, more recently researchers have discovered that sources from within the cell itself can sometimes be even more damaging.

7 Jan 2016

Scientists discover molecular mechanism responsible for degeneration of Purkinje cells in SCA1

Scientists from Bern have discovered a mechanism which is responsible for the degeneration of Purkinje cells in the cerebellum in a neurodegenerative disease called Spinocerebellar ataxia type 1. The results of their study open up new avenues for the future treatment of cerebellum associated degenerative disorders.

7 Jan 2016

Promising novel approach to treat gynecologic tumors

UCLA scientists have developed a promising novel method to treat gynecologic tumors. The approach focuses on a protein called p53, which is commonly mutated in women who have high-grade serous ovarian cancer, the deadliest form of reproductive cancer. In many women with the disease, the cancer is very advanced by the time it is diagnosed and is therefore difficult to treat.

7 Jan 2016

Injectable microwheels can effectively treat arterial blockages

Biomedical microwheel research conducted by members of the Colorado School of Mines Department of Chemical and Biological Engineering has been published in Nature Communications.

7 Jan 2016

Drexel biomedical engineer identifies immune cell as potential strategy for growing blood vessels

In what could be a pivotal step toward repairing non-healing wounds and damaged organs, a Drexel University biomedical engineer has identified an immune cell as a potential strategy for growing blood vessels.

7 Jan 2016

Low-oxygen exposure shortly after birth may increase learning and behavioral disorder risks

New research published in the Journal of Leukocyte Biology, shows that the development of white matter in the mouse brains is delayed when they are exposed to chronic low oxygen levels shortly after birth.

7 Jan 2016

Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

The conclusion drawn from a recent study that insertion of adeno-associated virus 2 (AAV2) into human DNA causes mutations leading to the development of hepatocellular carcinoma (HCC) was resoundingly rejected by leading researchers in the fields of gene therapy and molecular genetics.

7 Jan 2016

CUMC study reveals statins may help reduce heart disease risk in people with sleep apnea

A new study conducted at Columbia University Medical Center has revealed some of the underlying mechanisms that may increase the risk of heart disease in people with sleep apnea. The study also found that statins -- the cholesterol-lowering medications commonly prescribed to combat heart disease -- may help reverse this process.

7 Jan 2016

Discovery may pave way for more effective treatments for pandemics, seasonal flu

Scientists at Imperial College London have discovered how flu viruses 'hijack' cell machinery when they infect the body. The findings, published in the journal Nature, may pave the way for more effective antiviral treatments for pandemics and for seasonal flu, which infects over 800 million people worldwide every year.

7 Jan 2016

Insulin-producing cells' mitochondria may represent useful therapeutic target in type 2 diabetes

Factors in the blood from calorie-restricted rats can modify energy-producing mitochondria within the insulin-producing cells that regulate blood sugar levels, new research shows. This has a positive impact on glucose-stimulated insulin secretion and protects cells from fatty acid and glucose toxicity.

7 Jan 2016

Statins could be effective against metastatic small cell lung cancer

In a recent study, researchers at Cancer Treatment Centers of America at Western Regional Medical Center (Western), in collaboration with international colleagues, found that statins could be an effective therapeutic against metastatic small cell lung cancer (SCLC).

7 Jan 2016

Eliminating the 'bad seeds' of liver cancer

Researchers have found the 'bad seeds' of liver cancer and believe they could one day reprogram them to remain responsive to cancer treatment, a new study has found.

7 Jan 2016

Pediatric oncologists devise new treatments for neuroblastoma

Pediatric oncologists from The Children's Hospital of Philadelphia have reported their latest results in devising new treatments for stubbornly deadly forms of the childhood cancer neuroblastoma.

7 Jan 2016

Combining NELL-1 with BMP2 therapy may promote bone development

Bone morphogenetic protein-2 (BMP2) is used clinically to promote bone repair. However, the high BMP2 concentrations required to stimulate bone growth in humans may produce life-threatening adverse effects such as cervical swelling in spinal fusion procedures, a problem that prompted an FDA warning in 2008.

7 Jan 2016

Scientists develop a method for cell replacement in diseased vessels

In industrialized countries, a particularly high number of people suffer from arteriosclerosis -- with fatal consequences: Deposits in the arteries lead to strokes and heart attacks. A team of researchers under the leadership of the University of Bonn has now developed a method for guiding replacement cells to diseased vascular segments using nanoparticles.

7 Jan 2016

UF researchers reveal link between chronic stress and fat metabolism

In cell and mouse model experiments, University of Florida Health researchers have discovered that chronic stress stimulates production of betatrophin, a protein that then goes on to inhibit an enzyme involved in fat metabolism.

7 Jan 2016

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

DURECT Corporation today announced the successful completion of a Phase 1 clinical trial with an injectable formulation of DUR-928 intended for acute use indications. DUR-928 is an endogenous, small-molecule, new chemical entity (NCE), which may have broad applicability in metabolic diseases such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), and in acute organ injuries such as acute kidney injury (AKI).

6 Jan 2016

Cell News and Research

New class of sound wave could lead to revolution in stem cell therapy

Interpretation of images starts in the retina

Elsevier's new open access journal features novel method to make cancer clinical trials more effective

DNA damage may lead to mutation and changes in cell

Scientists discover molecular mechanism responsible for degeneration of Purkinje cells in SCA1

Promising novel approach to treat gynecologic tumors

Injectable microwheels can effectively treat arterial blockages

Drexel biomedical engineer identifies immune cell as potential strategy for growing blood vessels

Low-oxygen exposure shortly after birth may increase learning and behavioral disorder risks

Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

CUMC study reveals statins may help reduce heart disease risk in people with sleep apnea

Discovery may pave way for more effective treatments for pandemics, seasonal flu

Insulin-producing cells' mitochondria may represent useful therapeutic target in type 2 diabetes

Statins could be effective against metastatic small cell lung cancer

Eliminating the 'bad seeds' of liver cancer

Pediatric oncologists devise new treatments for neuroblastoma

Combining NELL-1 with BMP2 therapy may promote bone development

Scientists develop a method for cell replacement in diseased vessels

UF researchers reveal link between chronic stress and fat metabolism

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

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