Research News and Research

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Rural hospital closures impact the operations of surrounding healthcare institutions

Since 2005, more than 180 rural hospitals in the United States have closed, with nearly 1,000 more at risk of doing so.

13 Dec 2022

'Cellular glue' opens the door to building tissues and organs

Researchers at UC San Francisco have engineered molecules that act like "cellular glue," allowing them to direct in precise fashion how cells bond with each other.

13 Dec 2022

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Researchers assessed the impact of bebtelovimab (BEB) monoclonal antibody in the treatment of high-risk SARS-CoV-2 Omicron variant-infected patients.

13 Dec 2022

Study suggests persistent inflammatory response triggered by SARS-CoV-2 may be responsible for observed sequelae in PASC patients

Researchers assessed the association of enhanced migratory or activated CD8+ T cell and reduced avidity reactive cellular response due to post-acute COVID-19 syndrome (PASC).

13 Dec 2022

Scientists identify molecules in mucus that can block cholera infection

MIT researchers have identified molecules found in mucus that can block cholera infection by interfering with the genes that cause the microbe to switch into a harmful state.

13 Dec 2022

Vague, superficial advice given by doctors to patients living with obesity

A new research study published today in Family Practice, published by Oxford University Press, finds that when doctors tell patients living with obesity to lose weight the guidance they give is generally vague, superficial, and commonly not supported by scientific evidence.

13 Dec 2022

Study identifies factors linked to well-being as people age

What are the keys to "successful" or optimal aging? A new study followed more than 7000 middle-aged and older Canadians for approximately three years to identify the factors linked to well-being as we age.

13 Dec 2022

The effectiveness of nirmatrelvir-ritonavir and molnupiravir for the treatment of COVID-19 among US veterans

Researchers evaluated the effectiveness of SARS-CoV-2 antivirals, nirmatrelvir-ritonavir, and molnupiravir among Veterans in the United States of America.

13 Dec 2022

How Medicare Advantage plans dodged auditors and overcharged taxpayers by millions

In April 2016, government auditors asked a Blue Cross Medicare Advantage health plan in Minnesota to turn over medical records of patients treated by a podiatry practice whose owner had been indicted for fraud.

13 Dec 2022

Are you an optimist? Could you learn to be? Your health may depend on it.

When you think about the future, do you expect good or bad things to happen? If you weigh in on the "good" side, you're an optimist. And that has positive implications for your health in later life.

13 Dec 2022

Clinical efficacy and safety of two injections of a bivalent vaccine as a primary series during a period of Omicron circulation

Researchers evaluated the bivalent vaccine efficacy against the Omicron VOC.

13 Dec 2022

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

Researchers from The University of Texas MD Anderson Cancer Center are presenting compelling findings from three clinical trials at the 2022 American Society of Hematology Annual Meeting.

13 Dec 2022

Report makes recommendations clarifying the ethics and oversight of chimeric research

A new report on the ethics of crossing species boundaries by inserting human cells into nonhuman animals – research surrounded by debate – makes recommendations clarifying the ethical issues and calling for improved oversight of this work.

13 Dec 2022

RNA-targeting CRISPR technology alleviates disease-related phenotypes in Huntington’s models

Huntington's disease (HD) is a neurological disorder that causes progressive loss of movement, coordination and cognitive function.

12 Dec 2022

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

The nanomaterial graphene oxide - which is used in everything from electronics to sensors for biomolecules - can indirectly affect the immune system via the gut microbiome, as shown in a new study on zebrafish by researchers at Karolinska Institutet in Sweden.

12 Dec 2022

Poll: Most older Americans prefer to keep religious or spiritual beliefs separate from their health care

When it comes to matters of personal beliefs, most older Americans prefer to keep their health care and their spiritual or religious lives separate, a new University of Michigan poll finds.

12 Dec 2022

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

An international research team led by Dr Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into the mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior of the cell.

12 Dec 2022

Study discovers link between a lesser-known hormone and lipid levels in midlife women

Step aside estrogen. Scientists at the University of Pittsburgh have discovered a predictor of blood lipid - or cholesterol - status for midlife women that may be key to understanding how hormone replacement therapy contributes to heart health.

12 Dec 2022

New computer model can help researchers to spot which cells acquire alterations during development

Scientists at Johns Hopkins Medicine say they have developed a computer model - dubbed quantitative fate mapping - that looks back in the developmental timeline to trace the origin of cells in a fully grown organism

12 Dec 2022

Individuals with depression less likely to adhere to medications following percutaneous coronary intervention

Patients diagnosed with depression were less likely to adhere to essential medical therapies following percutaneous coronary intervention (PCI) than those without depression, according to a new study published in JAMA Network Open by researchers at the University of Pittsburgh School of Medicine.

12 Dec 2022

Research News and Research

Rural hospital closures impact the operations of surrounding healthcare institutions

'Cellular glue' opens the door to building tissues and organs

Study finds bebtelovimab therapy lacks efficacy in patients infected with SARS-CoV-2 Omicron subvariants

Study suggests persistent inflammatory response triggered by SARS-CoV-2 may be responsible for observed sequelae in PASC patients

Scientists identify molecules in mucus that can block cholera infection

Vague, superficial advice given by doctors to patients living with obesity

Study identifies factors linked to well-being as people age

The effectiveness of nirmatrelvir-ritonavir and molnupiravir for the treatment of COVID-19 among US veterans

How Medicare Advantage plans dodged auditors and overcharged taxpayers by millions

Are you an optimist? Could you learn to be? Your health may depend on it.

Clinical efficacy and safety of two injections of a bivalent vaccine as a primary series during a period of Omicron circulation

Targeted therapies and novel drug combinations show promise for the treatment of multiple leukemias

Report makes recommendations clarifying the ethics and oversight of chimeric research

RNA-targeting CRISPR technology alleviates disease-related phenotypes in Huntington’s models

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

Poll: Most older Americans prefer to keep religious or spiritual beliefs separate from their health care

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

Study discovers link between a lesser-known hormone and lipid levels in midlife women

New computer model can help researchers to spot which cells acquire alterations during development

Individuals with depression less likely to adhere to medications following percutaneous coronary intervention

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