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First precision medicine trial in lung cancer expands to include more patients

The Lung Cancer Master Protocol, the first precision medicine trial in lung cancer supported by the National Cancer Institute, part of the National Institutes of Health, is undergoing a major expansion to include patients with all non-small cell lung cancers -- which make up about 85 percent of all lung cancer diagnoses in the U.S.

29 Jan 2019

Cells in the intestines play key role in inducing acute inflammatory episodes

Medical researchers discover a type of cell which induces acute inflammatory episodes in bowel diseases.

29 Jan 2019

CHOP physician-researchers analyze opioid prescription patterns in children

As the opioid epidemic continues to plague the United States, physician-researchers at Children's Hospital of Philadelphia analyzed prescription patterns in children.

29 Jan 2019

Researchers identify effects of nanoparticles on intestinal microorganisms

The intestinal microbiome is not only key for food processing but an accepted co-determinant for various diseases. Researchers led by the University Medical Center of Johannes Gutenberg University Mainz identified effects of nanoparticles on intestinal microorganisms.

29 Jan 2019

Binge and heavy drinking may change DNA, resulting in greater desire for alcohol

Binge and heavy drinking may trigger a long-lasting genetic change, resulting in an even greater craving for alcohol, according to a Rutgers-led study in the journal Alcoholism: Clinical & Experimental Research.

29 Jan 2019

Community hospitals link arms with prestigious facilities to raise their profiles

After seven years of a vigorous fight, Jim Hart worried he was running out of options. Diagnosed with prostate cancer at age 60, Hart had undergone virtually every treatment — surgery, radiation and hormones — to eradicate it. But a blood test showed that his level of prostate-specific antigen, which should have been undetectable, kept rising ominously. And doctors couldn’t determine where the residual cancer was lurking.

29 Jan 2019

Sensyne collaborates with University of Oxford’s Big Data Institute to find solutions for chronic diseases

Sensyne Health plc. today announces a three-year collaboration with the University of Oxford to develop AI for chronic disease.

29 Jan 2019

Study adds more evidence to the link between hearing loss and cognitive decline

Hearing loss affects tens of millions of Americans and its global prevalence is expected to grow as the world's population ages. A new study led by investigators at Brigham and Women's Hospital adds to a growing body of evidence that hearing loss is associated with higher risk of cognitive decline.

29 Jan 2019

New study elucidates role of signaling molecule in development of myocarditis

Researchers of Ludwig-Maximilians-Universitaet in Munich have shown that a protein called midkine, a member of the class of signaling molecules known as cytokines, is a key driver of inflammation in the heart muscle that can lead to heart failure in patients with myocarditis.

29 Jan 2019

Human trials set to begin for testing new 'fat pill' in overweight patients

Are you overweight and living in the South East of England? If so, you could help scientists who need volunteers to test a new 'fat pill'.

29 Jan 2019

Two major forms of CD44 have distinct biological functions in breast cancer, shows study

One of the main obstacles to successfully treating breast cancer is the cells' ability to change in ways that make them resistant to treatment.

29 Jan 2019

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

A Massachusetts General Hospital (MGH) research team has found that the overgrowth of connective called fibrosis may block the effectiveness of immunotherapies against metastatic breast cancer.

29 Jan 2019

Study: Freestanding emergency departments charge more than urgent care centers

Freestanding emergency departments may charge more than urgent care centers (UCCs) to provide care for fewer patients who have similar characteristics and conditions, according to a study released in the Journal of Emergency Medicine.

29 Jan 2019

Stand Up To Cancer creates Dream Team focused on finding therapies for T-cell lymphoma

Stand Up To Cancer announced here today the creation of an $8 million Dream Team of top scientists focused on finding therapies for T-cell lymphoma, a rare cancer of the blood and immune system, using chimeric antigen receptors (CARs) to trigger the immune system to attack and destroy cancerous cells.

29 Jan 2019

RNA-induced gene fusion can occur in mammalian cells, reveals study

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome.

29 Jan 2019

New precision medicine treatment for bone cancer in dogs opens door for human clinical trials

In a first-of-its-kind study, scientists at the University of Missouri have helped advance a patient-specific, precision medicine treatment for bone cancer in dogs.

29 Jan 2019

New drug compounds show promise in treating acute myeloid leukemia

Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.

29 Jan 2019