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Strontium-loaded hydrogel scaffolds promote wound healing by stimulating gingival fibroblast activity

A team of University at Buffalo researchers has developed a new strontium-loaded scaffold that can be personalized to fit any size dental implant and could help improve healing and tissue attachment in patients.

9 Dec 2022

Structural studies pave the way for cancer drugs that could target only mutated versions

To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.

9 Dec 2022

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Oregon Health & Science University researchers and partners are developing what could become the first-ever treatment against the debilitating joint pain that can last months or years after becoming infected with the emerging Chikungunya virus.

9 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma.

9 Dec 2022

Overexpression of lncRNA MVIH may serve as a potential diagnostic biomarker in cervical cancer

A new research paper was published in Genes & Cancer on November 23, 2022, entitled, "Ectopic expression of lncRNA MVIH as a potential diagnostic biomarker in cervical cancer."

9 Dec 2022

Researchers discover a previously unknown mechanism that drives aging

Northwestern University researchers have discovered a previously unknown mechanism that drives aging.

9 Dec 2022

Johns Hopkins researchers characterize a broad range of psychedelic occasioned belief changes

Johns Hopkins Medicine researchers continue their exploration into psychedelics and how these drugs may produce a wide range of profound changes in perception, cognition and mood.

9 Dec 2022

Concrete steps for screening, detection and treatment of adolescent substance use

Despite advances in technology and availability, one of the best ways for parents and health care providers to prevent or help stop adolescent substance use is still an old-fashioned conversation, according to a new Viewpoint published in the November issue of The Lancet Child & Adolescent Health.

9 Dec 2022

Bariatric surgical procedures can lead to enduring improvements in urinary incontinence

Urinary incontinence is a common complaint among adults with severe obesity. The majority of adults with urinary incontinence who undergo Roux-en-Y gastric bypass or sleeve gastrectomy, the two most common types of weight loss surgery, can reasonably expect enduring improvements in urinary incontinence, according to a new study published today in JAMA Network Open.

9 Dec 2022

Mental health services for farmers in rural areas need urgent attention, say researchers

Mental health services in rural areas need urgent attention to ensure the needs of farmers are properly met, according to researchers.

9 Dec 2022

Study may allow patients with multiple breast lesions to consider breast-conserving therapy as treatment option

Patients with multiple tumors in the same breast who underwent a lumpectomy followed by radiation therapy had local recurrence rates comparable to those historically observed in patients with a single tumor, according to results from the ACOSOG Z11102 (Alliance) prospective phase II clinical trial, which were presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

WashU’s nasal COVID-19 vaccine authorized for emergency use in India as a booster

A nasal COVID-19 vaccine based on technology licensed from Washington University in St. Louis has been approved for emergency use in India as a booster for people who have already received two doses of other COVID-19 vaccines.

9 Dec 2022

Scientists trace how livestock systems act as a reservoir for antimicrobial-resistant bacteria

Scientists from the International Livestock Research Institute (ILRI), the University of Liverpool, the University of Edinburgh and elsewhere have traced how livestock systems act as a reservoir for antimicrobial-resistant (AMR) bacteria and AMR genetic determinants that may infect or colonize people.

9 Dec 2022

Study proposes a new concept for treating COVID-19 associated weight loss

Losing too much weight when infected with COVID-19 has been linked to worse outcomes. Now, researchers at Karolinska Institutet in Sweden have discovered that SARS-CoV-2 infection fuels blood vessel formation in fat tissues, thus revving up the body's thermogenic metabolism.

9 Dec 2022

HIV-positive people are protected by Covid vaccines

People infected with HIV who receive antiretroviral therapy form antibodies against Sars-Cov-2 after being vaccinated against Covid with mRNA vaccines.

9 Dec 2022

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

In patients with hormone receptor (HR)-positive, HER2-negative tumors resistant to aromatase inhibitors, addition of the investigational AKT inhibitor capivasertib to fulvestrant (Faslodex) doubled the median progression-free survival compared with placebo plus fulvestrant in the phase III CAPItello-291 clinical trial, according to results presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Patients with invasive breast cancer who had low scores on an investigational gene molecular signature had similar rates of local recurrence whether or not they received adjuvant radiation therapy after breast-conserving surgery, according to results of a meta-analysis presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

9 Dec 2022

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points.

9 Dec 2022

Landmark study challenges a 70-year-old theory of protein folding

A landmark study by researchers at the Department of Energy’s SLAC National Accelerator Laboratory and Stanford University reveals how a tiny cellular machine called TRiC directs the folding of tubulin, a human protein that is the building block of microtubules that serve as the cell’s scaffolding and transport system.

9 Dec 2022

Research News and Research

Strontium-loaded hydrogel scaffolds promote wound healing by stimulating gingival fibroblast activity

Structural studies pave the way for cancer drugs that could target only mutated versions

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

An epigenetic modification improves the defense against infections, research shows

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

Overexpression of lncRNA MVIH may serve as a potential diagnostic biomarker in cervical cancer

Researchers discover a previously unknown mechanism that drives aging

Johns Hopkins researchers characterize a broad range of psychedelic occasioned belief changes

Concrete steps for screening, detection and treatment of adolescent substance use

Bariatric surgical procedures can lead to enduring improvements in urinary incontinence

Mental health services for farmers in rural areas need urgent attention, say researchers

Study may allow patients with multiple breast lesions to consider breast-conserving therapy as treatment option

WashU’s nasal COVID-19 vaccine authorized for emergency use in India as a booster

Scientists trace how livestock systems act as a reservoir for antimicrobial-resistant bacteria

Study proposes a new concept for treating COVID-19 associated weight loss

HIV-positive people are protected by Covid vaccines

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

POLAR gene profile predicts which patients may and may not benefit from radiation therapy after breast-conserving surgery

Researchers develop transgenic mice with the FRET biosensor for in vivo observation of necroptosis

Landmark study challenges a 70-year-old theory of protein folding

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