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Researchers discover promising new compound against Buruli ulcer

Buruli ulcer - one of the most neglected among the NTDs - is a debilitating and stigmatizing disease. Affecting mainly children in West and Central Africa, the chronic disease results in devastating skin lesions and can lead to permanent disfigurement and long-term disabilities.

18 Dec 2018

Study finds significant use of traditional, complementary and alternative medicines in Sub-Saharan Africa

Researchers who have undertaken the first systematic review of into the use of traditional, complementary and alternative medicines in Sub-Saharan Africa found its use is significant and not just because of a lack of resources or access to "conventional medicine".

18 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

New app accurately measures and charts progression of skin wounds

Monitoring a wound is critical, especially in diabetic patients, whose lack of sensation due to nerve damage can lead to infection of a lesion and, ultimately, amputation.

18 Dec 2018

Study examines relationship between growth restriction and risk of childhood mortality

Almost all children live to see their eighteenth birthday despite a severe growth restriction, as long as they have survived their first month during infancy. This is indicated in a study by researchers at Karolinska Institutet, which is published in the journal PLOS Medicine.

18 Dec 2018

Metal-based chemotherapy enhances the effect of cancer immunotherapy

Due to their powerful tumor-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) effect even against dividing healthy cells.

18 Dec 2018

New genetic testing method increases the precision of biomarker analysis

Estonian scientists have announced the invention of a genetic testing technology that allows the number of clinical biomarkers to be analyzed at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future.

18 Dec 2018

Sickest children could benefit from split liver transplants

In a review of registry data for more than 5,300 liver transplants performed in children nationwide, Johns Hopkins Medicine researchers identify the type of patient who is most likely to survive a split liver transplant--receiving only part of a donor's liver--with no additional long-term health risks, which could allow for an increase in the availability of organs.

18 Dec 2018

Mouse study uncovers how marijuana may damage some adolescent brains

In a study of adolescent mice with a version of a gene linked to serious human mental illnesses, Johns Hopkins Medicine researchers say they have uncovered a possible explanation for how marijuana may damage the brains of some human teens.

18 Dec 2018

McMaster study: Your postal code may play a role in your risk of major diseases

Where you live in Canada may play a role in your risk of major diseases like cardiovascular disease, diabetes and cancer.

18 Dec 2018

Research suggests a promising therapeutic target to treat or prevent metabolic disorders

Research led by Suresh Alahari, PhD, Fred Brazda Professor of Biochemistry and Microbiology at LSU Health New Orleans, suggests a novel protein may be a promising therapeutic target to treat or prevent metabolic disorders.

18 Dec 2018

Parental alcohol use disorder associated with offspring marital outcomes

Children of parents who have alcohol use disorder are more likely to get married under the age of 25, less likely to get married later in life, and more likely to marry a person who has alcohol use disorder themselves, according to a new study by researchers at Virginia Commonwealth University and Lund University in Sweden.

18 Dec 2018

UI study leads to better understanding of signaling capacity between neurons

The fundamental process of information transfer from neuron to neuron occurs through a relay of electrical and chemical signaling at the synapse, the junction between neurons. Electrical signals, called action potentials, cause voltage-gated calcium channels on the presynaptic neuron to open.

18 Dec 2018

Intraocular injection improves vision in a form of congenital retinal blindness

A new treatment for patients with a form of congenital retinal blindness has shown success in improving vision, according to results published today in Nature Medicine led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania.

18 Dec 2018

Early postpartum initiation of opioids associated with persistent use

Vanderbilt researchers have published findings indicating that regardless of whether a woman delivers a child by cesarean section or by vaginal birth, if they fill prescriptions for opioid pain medications early in the postpartum period, they are at increased risk of developing persistent opioid use.

18 Dec 2018

Advanced method can help detect multiple markers that contribute to Alzheimer's disease

In biomedical research, plant breeding, and countless other endeavors, geneticists are on the hunt for the specific genes responsible for disease susceptibility, yield, and other traits of interest.

17 Dec 2018

New study reveals best assessment tools to establish delirium severity

A study published today in JAMA Internal Medicine reveals the best assessment tools available to establish the severity of diagnosed delirium in hospitalized patients. Delirium is a common, serious, and often preventable complication among older adult patients.

17 Dec 2018

Scientists create patient-specific model to identify most effective treatment for appendix cancer

Scientists at the Wake Forest Institute for Regenerative Medicine have recently developed a process that may change the way cancer of the appendix is treated in the future.

17 Dec 2018

New study confirms geographic bias in lung allocation for transplant

Results of a medical records study of more than 7,000 patients awaiting a lung transplant in the United States affirm the basis of a court filing in 2017 that called the organ allocation system geographically "rigged" in some regions of the nation.

17 Dec 2018

New approach to tumor analysis could improve prognosis for bowel cancer patients

Bowel (colorectal) cancer is the third most commonly occurring cancer in men and the second most commonly occurring cancer in women worldwide. The global burden is expected to increase by 60 per cent to more than 2.2 million new cases and 1.1 million deaths by 2030.

17 Dec 2018