Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Catheter ablation more beneficial to heart failure patients than Amiodarone treatment

Among patients with heart failure and atrial fibrillation, those who underwent catheter ablation were less likely to die, be hospitalized or have recurrent atrial fibrillation than patients taking a heart rhythm regulating drug, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

19 Mar 2015

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as "the long-sought culprit" in the mystery behind a cell-signaling breakdown that triggers heart failure. The condition, which affects nearly 6 million Americans and 23 million people worldwide, is marked by progressive weakening and stiffening of the heart muscle and the organ's gradual loss of blood-pumping ability.

19 Mar 2015

New research lays groundwork for developing treatments for asthma, COPD

In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production.

18 Mar 2015

Transcatheter MitraClip system safe, effective for valve repair treatment

The commercial track record with transcatheter mitral valve repair, approved for patients at high risk for surgery, compares favorably with pre-approval reports, according to findings from a U.S. registry presented at the American College of Cardiology's 64th Annual Scientific Session.

18 Mar 2015

New drug fails to prevent irreversible injury to the heart after angioplasty

Patients who received the new drug Bendavia before undergoing angioplasty or receiving a stent to clear blocked arteries after a heart attack showed no significant reduction in scarring as compared to patients given a placebo, according to a study presented at the American College of Cardiology's 64th Annual Scientific Session.

18 Mar 2015

Baroreflex activation therapy safe, effective for symptomatic advanced heart failure patients

Results of a clinical trial announced today at the American College of Cardiology Annual Scientific Session show a new type of therapy is safe and effective for symptomatic advanced heart failure patients who are already receiving optimum drug and device therapy.

17 Mar 2015

Routine use of thrombectomy in heart attack patients may increase risk of stroke

The largest study ever of its kind, led by researchers from McMaster University and the University of Toronto, has found that a routine strategy of blood clot removal during treatment for heart attacks was not beneficial and was associated with an increased risk of stroke.

17 Mar 2015

Endovascular aneurysm repair procedure can extend lives even in high-risk patients: Study

Minimally invasive surgery can prevent a fatal rupture of an abdominal aortic aneurysm.

17 Mar 2015

Sugar-lowering medications prescribed to diabetic patients may increase heart failure risk

A comprehensive study examining clinical trials of more than 95,000 patients has found that glucose or sugar-lowering medications prescribed to patients with diabetes may pose an increased risk for the development of heart failure in these patients.

17 Mar 2015

Endo announces commercial availability of NATESTO nasal gel for men with hypogonadism

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc (NASDAQ: ENDP) (TSX: ENL), announced today the commercial availability of NATESTO (testosterone nasal gel), the first and only nasal gel for testosterone replacement therapy in adult males diagnosed with hypogonadism.

16 Mar 2015

Islet autoantibody levels predict progression to diabetes

Levels of insulin autoantibodies and insulinoma-associated protein 2 autoantibodies predict the onset of diabetes in young children with islet autoimmunity, show findings from the TEDDY study.

13 Mar 2015

New study explores patient outcomes one year after TAVR procedure

In an analysis of outcomes of about 12,000 patients who underwent transcatheter aortic valve replacement, death rate after one year was nearly one in four; of those alive at 12 months, almost half had not been rehospitalized and approximately 25 percent had only one hospitalization, according to a study in the March 10 issue of JAMA.

12 Mar 2015

Rehospitalizations after severe sepsis may be potentially preventable

In an analysis of about 2,600 hospitalizations for severe sepsis, readmissions within 90 days were common, and approximately 40 percent occurred for diagnoses that could potentially be prevented or treated early to avoid hospitalization, according to a study in the March 10 issue of JAMA.

12 Mar 2015

Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Ablative Solutions, Inc., a venture-backed, privately-held clinical stage company headquartered in Kalamazoo, MI, with offices in Menlo Park, CA, announced today that it was the recipient of a "Top Cardiovascular Innovation Award" from Cardiovascular Research Technologies for the Peregrine System.

12 Mar 2015

Chronic heart failure patients with decreased calcitriol may benefit from aggressive supplementation

In patients with chronic heart failure, the vitamin D metabolite 1,25-dihydroxyvitamin D (1,25(OH)2D), also called calcitriol, and its ratio to parathyroid hormone (PTH 1-84) may help predict cardiovascular death; and patients with decreased calcitriol and decreased ratio of calcitriol to PTH might benefit from more aggressive supplementation, a new study finds.

9 Mar 2015

Severe mortality-associated diseases less prevalent in members of long-lived families

Recent research from the Long Life Family Study (LLFS) confirms that severe mortality-associated diseases are less prevalent in the families of long-lived individuals than in the general population. The Journals of Gerontology, Series A will publish these findings in the article titled, "Are Members of Long-Lived Families Healthier than Their Equally Long-Lived Peers? Evidence from the Long Life Family Study" on March 5, 2015.

6 Mar 2015

Screening for and treating depression could help reduce risk of heart disease

A new study by researchers at the Intermountain Medical Center Heart Institute has found that screening for and treating depression could help to reduce the risk of heart disease in patients with moderate to severe depression.

6 Mar 2015

RBFox2 protein plays critical role in heart failure

Researchers at the University of California, San Diego School of Medicine have identified a key piece in the complex molecular puzzle underlying heart failure - a serious and sometimes life-threatening disorder affecting more than 5 million Americans.

5 Mar 2015

Study: Omega-3 fatty acids appear to protect heart function among heart attack survivors

Taking omega-3 fatty acids appeared to lower inflammation and guard against further declines in heart function among recent heart attack survivors already receiving optimal standard care, according to results from a randomized, controlled trial to be presented at the American College of Cardiology's 64th Annual Scientific Session in San Diego.

5 Mar 2015

Common antidepressant medications not helpful for people with mood, anxiety disorders

Studies indicate that the majority of people with mood and anxiety disorders who receive the most commonly prescribed class of antidepressant medications, Selective Serotonin Reuptake Inhibitors or SSRI's, are not helped by these medications. SSRIs are designed to increase serotonin, a neurotransmitter in the brain that is key to maintenance of mood.

4 Mar 2015

Heart Failure News and Research

Further Reading

Catheter ablation more beneficial to heart failure patients than Amiodarone treatment

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

New research lays groundwork for developing treatments for asthma, COPD

Transcatheter MitraClip system safe, effective for valve repair treatment

New drug fails to prevent irreversible injury to the heart after angioplasty

Baroreflex activation therapy safe, effective for symptomatic advanced heart failure patients

Routine use of thrombectomy in heart attack patients may increase risk of stroke

Endovascular aneurysm repair procedure can extend lives even in high-risk patients: Study

Sugar-lowering medications prescribed to diabetic patients may increase heart failure risk

Endo announces commercial availability of NATESTO nasal gel for men with hypogonadism

Islet autoantibody levels predict progression to diabetes

New study explores patient outcomes one year after TAVR procedure

Rehospitalizations after severe sepsis may be potentially preventable

Ablative Solutions named recipient of CRT's Top Cardiovascular Innovation Award

Chronic heart failure patients with decreased calcitriol may benefit from aggressive supplementation

Severe mortality-associated diseases less prevalent in members of long-lived families

Screening for and treating depression could help reduce risk of heart disease

RBFox2 protein plays critical role in heart failure

Study: Omega-3 fatty acids appear to protect heart function among heart attack survivors

Common antidepressant medications not helpful for people with mood, anxiety disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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