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XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

An experimental anti-inflammatory drug can protect vulnerable neurons and reduce motor deficits in a rat model of Parkinson's disease, researchers at Emory University School of Medicine have shown.

26 Jul 2014

Study: Slow walking, memory complaints may predict future dementia

A study involving nearly 27,000 older adults on five continents found that nearly 1 in 10 met criteria for pre-dementia based on a simple test that measures how fast people walk and whether they have cognitive complaints.

26 Jul 2014

Albuminuria change is a strong cardiovascular risk indicator in diabetes

Changes in albuminuria predict cardiovascular mortality and morbidity over and above glucose levels and blood pressure, say researchers.

25 Jul 2014

BU researchers find possible way to prevent Alzheimer's disease

Boston University School of Medicine researchers may have found a way to delay or even prevent Alzheimer's disease (AD). They discovered that pre-treatment of neurons with the anti-aging protein Klotho can prevent neuron death in the presence of the toxic amyloid protein and glutamate.

25 Jul 2014

EMA recommends full marketing approval for IMBRUVICA in the European Union

Pharmacyclics, Inc. today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency issued a positive opinion recommending the granting of full marketing approval for IMBRUVICA (ibrutinib) in the European Union.

25 Jul 2014

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells.

25 Jul 2014

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Over half of patients being seen in the clinic for a diagnosed brain tumor have metastatic cancer, which has no treatment and detrimental outcomes in most cases.

25 Jul 2014

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

25 Jul 2014

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation.

25 Jul 2014

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Bayer HealthCare and Onyx Pharmaceuticals Inc., an Amgen subsidiary, today announced that an investigational Phase 3 trial of NEXAVAR (sorafenib) tablets in patients with advanced breast cancer did not meet its primary endpoint of improving progression-free survival (PFS).

25 Jul 2014

Incisionless TAVR surgery cuts length of hospital stay by 30%

New research from Penn Medicine shows that incisionless transcatheter aortic valve replacement (TAVR) surgery cuts length of hospital stay by 30 percent and has no impact on post-operative vascular complication rates when compared with conventional transfemoral TAVR, which requires an incision in the groin.

25 Jul 2014

Blacks with depression and diabetes receive inadequate mental health treatment

A new study in General Hospital Psychiatry confirms that Blacks with depression plus another chronic medical condition, such as Type 2 diabetes or high blood pressure, do not receive adequate mental health treatment.

25 Jul 2014

Researchers recommend low carbohydrate diet for Type 1 and Type 2 diabetes

A new study involving researchers from the University of Alabama at Birmingham and other institutions says patients with Type 1 and Type 2 diabetes should eat a diet low in carbohydrates.

25 Jul 2014

Children who experience stress early in life have emotional, physical health problems

Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems.

25 Jul 2014

$1,000-a-pill hepatitis C drug boosts Gilead's fortunes

Sales of the new hepatitis C drug Sovaldi reached $3.5 billion in the second quarter, putting it on track to become one of the world's best-selling medicines and intensifying concerns about its costs.

25 Jul 2014

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system.

25 Jul 2014

Researchers examine association between ritual circumcision procedure and HSV-1 in infants

A rare procedure occasionally performed during Jewish circumcisions that involves direct oral suction is a likely source of herpes simplex virus type 1 (HSV-1) transmissions documented in infants between 1988 and 2012, a literature review conducted by Penn Medicine researchers and published online in the Journal of the Pediatric Infectious Disease Society found.

25 Jul 2014

Researchers working to develop new drugs for treating chronic inflammatory diseases

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong.

25 Jul 2014

Immune system play role in memory impairment associated with chronic epilepsy

Could the body's own immune system play a role in memory impairment and cognitive dysfunction associated with conditions like chronic epilepsy, Alzheimer's dementia and concussions? Cleveland Clinic researchers believe so, based on a study published online by PLOS ONE.

25 Jul 2014

Newcomer among arboviruses: The zika virus

In the group of viruses that includes dengue and chikungunya, a newcomer now has people talking about it. Also originating in Africa, zika was isolated in humans in the 1970s. Several years earlier, only a few human cases had been reported.

25 Jul 2014

Blood News and Research

XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

Study: Slow walking, memory complaints may predict future dementia

Albuminuria change is a strong cardiovascular risk indicator in diabetes

BU researchers find possible way to prevent Alzheimer's disease

EMA recommends full marketing approval for IMBRUVICA in the European Union

Autophagy prevents accumulation of toxic proteins associated with type 2 diabetes

CCC study provides hope that SapC-DOPS could be used for metastatic brain cancer treatment

Study identifies molecular mechanisms could lead to new therapies to treat obesity, diabetes

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Incisionless TAVR surgery cuts length of hospital stay by 30%

Blacks with depression and diabetes receive inadequate mental health treatment

Researchers recommend low carbohydrate diet for Type 1 and Type 2 diabetes

Children who experience stress early in life have emotional, physical health problems

$1,000-a-pill hepatitis C drug boosts Gilead's fortunes

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers examine association between ritual circumcision procedure and HSV-1 in infants

Researchers working to develop new drugs for treating chronic inflammatory diseases

Immune system play role in memory impairment associated with chronic epilepsy

Newcomer among arboviruses: The zika virus

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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