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How Patch Clamp Technology Can Benefit Ion Channel Research

Learn how patch clamp technology meets high-throughput to benefit ion channel research in this interview with Tim and James, Nanion.

From Nanion Technologies 16 Jan 2019

GoFundMe CEO: ‘Gigantic gaps’ in health system showing up in crowdfunding

Scrolling through the GoFundMe website reveals seemingly an endless number of people who need help or community support. A common theme: the cost of health care.

16 Jan 2019

MAR treatments unlikely to be cause of premature or low birth weight babies

Children born through medically assisted reproduction, such as IVF, are at higher risk of being premature and to be born low birth weight, but it’s unlikely to be due to the procedures used, according to a new study published in The Lancet from the London School of Economics and Political Science.

14 Jan 2019

Synthetic compound reverses mutant p53 aggregate accumulation, study shows

Cancer is a multidisciplinary disease, with different mutations leading to different prognoses and treatment necessities. Among the most important mutation targets in cancers, affecting more than 50% of all cancer cases, is TP53.

14 Jan 2019

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Millions of people suffer from inflammatory bowel disease worldwide, either in the form of ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD.

9 Jan 2019

Study: Rutin found in fruits and vegetables protect mice against snake venom

Rutin, a bioflavonoid found in certain vegetables and fruits, protects mice against snake venom by minimizing bleeding and inflammation, according to a study performed at the Butantan Institute, a research institution belonging to the government of São Paulo State in Brazil.

9 Jan 2019

KU researcher studies how estrogen may protect menisci between thighbone and shinbone

More than 30 million Americans suffer from osteoarthritis of the knee, according to the Centers for Disease Control and Prevention.

9 Jan 2019

New molecular engineering method improves precision of biomarker analysis

Researchers from the University of Helsinki in cooperation with the University of Tartu, Competence Centre on Health Technologies from Estonia, and the Karolinska Institute, published an article in Nature's partner journal Genomic Medicine in which they present Targeted Allele Counting by sequencing along with several of its potential applications.

8 Jan 2019

Scientists demonstrate potential of imaging technique based on physical properties of tumors

A team of physicists at the Institut Lumière Matière, in collaboration with the Cancer Research Center of Lyon, has demonstrated the potential, for oncology, of an imaging technique based only on the physical properties of tumors.

8 Jan 2019

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Researchers from LSTM and the University of Liverpool have successfully optimized a hit from a whole cell screening of a 10000-compound library to deliver the first novel fully synthetic and rationally designed anti-Wolbachia drug, AWZ1066S, which could potentially be used to treat onchocerciasis and lymphatic filariasis.

8 Jan 2019

Insilico Medicine and TARA Biosystems collaborate to develop novel therapies for cardiac diseases

Insilico Medicine, an artificial intelligence company developing end-to-end drug discovery pipelines for age-related diseases and TARA Biosystems, Inc. a company offering "heart-on-a-chip" tissue models for drug discovery and risk assessment applications, announced today the launch of a collaboration to discover and develop novel therapies for cardiac disease and diseases associated with cardiac muscle aging.

8 Jan 2019

New editorial proposes changes to improve minority representation in clinical trials

In an editorial published in CNS Spectrums, Jay Avasarala, MD, PhD, takes the research community to task for its lack of minority representation in Phase III clinical trials for drugs to treat Multiple Sclerosis (MS).

2 Jan 2019

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

Treatment for low-grade gliomas in patients living with neurofibromatosis type 1 are now one step closer thanks to recent research discoveries initiated and funded by the Children's Tumor Foundation.

28 Dec 2018

New review focuses on the structure-activity relationships of flavonoids

ABCB1 in the ABC transporter family also termed as P-glycoprotein, grants the simultaneous resistance of metastatic cancer cells towards various anti-cancer drugs with different targets and diverse chemical structures.

27 Dec 2018

Soyasapogenol B: A new drug delivery technology for therapeutics

Multi-Walled Carbon Nanotubes (MWCNTs) are characterized by walls formed by a one atom thick sheet of carbon.

24 Dec 2018

New bacteria-based drug delivery system could radically expand cancer treatment options

An interdisciplinary team of three Virginia Tech faculty members affiliated with the Macromolecules Innovation Institute has created a drug delivery system that could radically expand cancer treatment options.

21 Dec 2018

Researchers find new way to cut the power of tumors

Instead of tackling tumors head-on, an international team of researchers from the University of Geneva and the Amsterdam UMC, location VUmc in Amsterdam has chosen to regulate their vascularization by intervening with cellular receptor that is overexpressed specifically in cancer blood vessels.

20 Dec 2018

Researchers synthesize new compound that inhibits replication of hepatitis C virus

A new compound that inhibits the replication of hepatitis C virus in several stages of its lifecycle - and is also capable of acting on bacteria, fungi and cancer cells - has been synthesized by researchers at São Paulo State University in Brazil.

19 Dec 2018

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

An international team coordinated by the Interdisciplinary Research Structure in Biotechnology and Biomedicine of the University of Valencia has proved how the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to the biochemical research for decades.

19 Dec 2018

Study reveals how stem cells can be induced to differentiate into various ocular lineages

The discovery of pluripotent stem cells, which have the ability to differentiate into the huge range of different cell lineages that make up the human body, signaled the start of a new era in biological science and medicine. Although we are also now able to reprogram regular cells to exhibit this pluripotency, we still have much to learn about the different cues that lead such cells towards a particular cell fate, including the cells that make up the eye.

19 Dec 2018

in vitro News and Research

How Patch Clamp Technology Can Benefit Ion Channel Research

GoFundMe CEO: ‘Gigantic gaps’ in health system showing up in crowdfunding

MAR treatments unlikely to be cause of premature or low birth weight babies

Synthetic compound reverses mutant p53 aggregate accumulation, study shows

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Study: Rutin found in fruits and vegetables protect mice against snake venom

KU researcher studies how estrogen may protect menisci between thighbone and shinbone

New molecular engineering method improves precision of biomarker analysis

Scientists demonstrate potential of imaging technique based on physical properties of tumors

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Insilico Medicine and TARA Biosystems collaborate to develop novel therapies for cardiac diseases

New editorial proposes changes to improve minority representation in clinical trials

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

New review focuses on the structure-activity relationships of flavonoids

Soyasapogenol B: A new drug delivery technology for therapeutics

New bacteria-based drug delivery system could radically expand cancer treatment options

Researchers find new way to cut the power of tumors

Researchers synthesize new compound that inhibits replication of hepatitis C virus

Study uncovers initial folding mechanism of membrane proteins, key in design of new drugs

Study reveals how stem cells can be induced to differentiate into various ocular lineages

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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