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Researchers discover promising new compound against Buruli ulcer

Buruli ulcer - one of the most neglected among the NTDs - is a debilitating and stigmatizing disease. Affecting mainly children in West and Central Africa, the chronic disease results in devastating skin lesions and can lead to permanent disfigurement and long-term disabilities.

18 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

New genetic testing method increases the precision of biomarker analysis

Estonian scientists have announced the invention of a genetic testing technology that allows the number of clinical biomarkers to be analyzed at the single-molecule level, which enhances the sensitivity of tests in precision medicine and will make them more affordable in future.

18 Dec 2018

Research focuses on optimization of solid lipid nanoparticle that encapsulates Vinorelbine bitartrate

Vinorelbine Bitartrate, a semi-synthetic vinca alkaloid was approved by the FDA for breast cancer treatment, as it has been proven to be beneficial for first line of defense and subsequent therapies. But its hydrophilic and thermolabile structure causes hindrance to oral clinical translation.

17 Dec 2018

CTF along with NTAP and Sage announce first-ever open data portal for neurofibromatosis

The Children's Tumor Foundation, together with the Neurofibromatosis Therapeutic Acceleration Program and Sage Bionetworks, has announced the first-ever open data portal for scientific research results in the field of neurofibromatosis.

17 Dec 2018

Using machine learning to predict risk of developing life-threatening infections

Staphylococcus epidermidis is an ubiquitous colonizer of healthy human skin, but it is also a notorious source of serious nosocomial infections with indwelling devices and surgical procedures such as hip replacements.

14 Dec 2018

Recent developments and challenges in hMAT inhibitors

Zhu et al. have reviewed the recent developments in the knowledge about the binding, inhibitory mechanisms and structure-activity relationships of hSERT, hNET and hDAT, which are primary human monoamine transporters hMATs.

14 Dec 2018

Scientists develop new stem cell line to study conversion of stem cells into muscle

To help patients with muscle disorders, scientists at The University of Texas Health Science Center at Houston (UTHealth) have engineered a new stem cell line to study the conversion of stem cells into muscle. Findings appeared in Cell Reports.

13 Dec 2018

Scientists use water molecules to track electrical activity of nerve cells

Researchers have discovered a new way to monitor electrical activity in nerve cells; by observing water molecules surrounding neuronal membranes.

11 Dec 2018

New method uses water molecules to unlock neurons' secrets

Neurons are brain cells that communicate with each other by sending electrochemical signals along axons. When a neuron is about to release a signal - in the form of an electric charge - it allows ions to pass through its membrane via ion channels.

11 Dec 2018

Researchers develop new system for efficiently producing human norovirus

An Osaka University-led research team has developed a system for simply and efficiently producing human norovirus. By coaxing human induced pluripotent stem cells to develop into a type of cell that usually lines the intestine, they created a cellular environment that can be used for producing the virus, studying how it interacts with human cells, and investigating potential vaccines.

11 Dec 2018

Novel personalized medicine tool for assessing inherited colorectal cancer syndrome risk developed

An international team of researchers led by Huntsman Cancer Institute at the University of Utah has developed, calibrated, and validated a novel tool for identifying the genetic changes in Lynch syndrome genes that are likely to be responsible for causing symptoms of the disease.

10 Dec 2018

New massive sequencing platform implemented for double factor preimplantation genetic testing

A research team from the Universitat Autònoma de Barcelona, in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Preimplantation Genetic Testing for the first time in history.

5 Dec 2018

The Lancet study: First baby born following uterus transplantation from deceased donor

Currently, uterus donation is only available for women with family members who are willing to donate. With live donors in short supply, the new technique might help to increase availability and give more women the option of pregnancy.

5 Dec 2018

Successful delivery after womb transplant

A Brazilian woman became the first woman to successfully deliver a baby after having received a womb transplant from a dead donor.

4 Dec 2018

New study supports use of ZnO nanoparticles in sunscreens

Zinc oxide has long been recognized as an effective sunscreen agent. However, there have been calls for sunscreens containing ZnO nanoparticles to be banned because of potential toxicity and the need for caution in the absence of safety data in humans.

4 Dec 2018

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

In a piece of research conducted in collaboration, the NanoBioCel group of the UPV/EHU's Faculty of Pharmacy, and the University of Elche have designed some niosomes, which are lipid vesicles for use in gene therapies designed to treat diseases of the central nervous system.

4 Dec 2018

New ointment for treating brown recluse spider bites is tested on humans

The bite from a brown recluse spider (Loxosceles) can cause skin necrosis, renal failure, and even death. A new ointment is being tested in Brazil, however. Its effects have already been proven in tests conducted in cell cultures and animal models.

29 Nov 2018

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

Given this morning's reports of infants possibly born in China whose genomes were edited by CRISPR-based technology, the American Society of Human Genetics (ASHG) reaffirms the cautious but proactive approach recommended in its 2017 position statement on human germline genome editing, published in The American Journal of Human Genetics.

26 Nov 2018

Certain dietary supplements can have beneficial effect on sperm quality, study suggests

Infertility affects 15% of the world population and is recognized by the World Health Organisation as a global health problem.

26 Nov 2018

in vitro News and Research

Researchers discover promising new compound against Buruli ulcer

Researchers identify link between mucus in the small airways and pulmonary fibrosis

New genetic testing method increases the precision of biomarker analysis

Research focuses on optimization of solid lipid nanoparticle that encapsulates Vinorelbine bitartrate

CTF along with NTAP and Sage announce first-ever open data portal for neurofibromatosis

Using machine learning to predict risk of developing life-threatening infections

Recent developments and challenges in hMAT inhibitors

Scientists develop new stem cell line to study conversion of stem cells into muscle

Scientists use water molecules to track electrical activity of nerve cells

New method uses water molecules to unlock neurons' secrets

Researchers develop new system for efficiently producing human norovirus

Novel personalized medicine tool for assessing inherited colorectal cancer syndrome risk developed

New massive sequencing platform implemented for double factor preimplantation genetic testing

The Lancet study: First baby born following uterus transplantation from deceased donor

Successful delivery after womb transplant

New study supports use of ZnO nanoparticles in sunscreens

NanoBioCel group develops lipid vesicles that can genetic material efficiently and viably

New ointment for treating brown recluse spider bites is tested on humans

ASHG reaffirms cautious but proactive approach recommended in its 2017 position statement on germline genome editing

Certain dietary supplements can have beneficial effect on sperm quality, study suggests

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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