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New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

Researchers offer new insights into the neurobiological basis of autism spectrum disorders

Findings from a new study published in Cell Reports, involving a collaborative effort between researchers at the Luikart Laboratory at Dartmouth's Geisel School of Medicine and the Weston Laboratory at the University of Vermont, are providing further insight into the neurobiological basis of autism spectrum disorders (ASD) and pointing to possible treatments.

1 Nov 2022

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

First pig-to-human cardiac transplant alters heart's electrical signals

A recent study to be presented at the American Heart Association (AHA) Scientific Sessions 2022* revealed unexpected changes in the electrical conduction system of the first genetically-modified porcine-to-human heart xenotransplant.

1 Nov 2022

Study provides a broader picture of consumer dining behavior during COVID-19 pandemic

The COVID-19 pandemic was marked by uncertainty. As public places slowly began reopening, people had to grapple with the risk they were willing to take for activities like in-person shopping or eating at a restaurant.

1 Nov 2022

New research lays the foundation for more effectively treating pediatric brain tumor

In a ground-breaking new study, scientists have uncovered the mechanics of the blood-tumor barrier, one of the most significant obstacles to improving treatment efficacy and preventing the return of cancerous cells.

1 Nov 2022

New method helps gain fundamental insights into ribosome function

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids that exit the ribosome as proteins.

1 Nov 2022

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Approximately one-fourth of the general population worldwide has nonalcoholic fatty liver disease, known as NAFLD, an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. NAFLD can lead to cirrhosis, liver cancer and liver failure.

1 Nov 2022

Rutgers study finds substantial inequities in access to specialty epilepsy care in New Jersey

For millions of Americans who suffer from epilepsy, advanced monitoring is essential for diagnosis and effective treatment. But in New Jersey, accessing these services is difficult for patients from racial and ethnic minority groups, according to a Rutgers study.

1 Nov 2022

The maternal RSV vaccine from Pfizer protects newborns against severe illness

Pfizer announced its maternal vaccine against RSV to be almost 82% effective in protecting infants for the first 90 days of life against severe illness.

1 Nov 2022

New review elucidates current treatment approaches for myelodysplastic syndromes

Physician scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have published a review in the Journal of the American Medical Association that clarifies current treatment approaches for myelodysplastic syndromes (MDS), which are rare and often deadly bone marrow cancers.

1 Nov 2022

UT Southwestern study uncovers a causative signaling pathway in breast cancer

UT Southwestern researchers have identified a causative signaling pathway in breast cancer, providing potential new targets for treatment of the most common type of cancer in women.

1 Nov 2022

First preclinical model to study the pathobiology of appendiceal cancer

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year.

1 Nov 2022

Social and economic inequality associated with differences in children's brain connections

Growing up in a socioeconomically disadvantaged household may have lasting effects on children's brain development, a large new study suggests.

1 Nov 2022

Study provides insight into how sleep and wakefulness regulate inhibitory synapses

Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity.

1 Nov 2022

Hospital investigated for allegedly denying an emergency abortion after patient’s water broke

The federal government has launched its first confirmed investigation of an alleged denial of an abortion to a woman experiencing a medical emergency.

1 Nov 2022

EULAR points-to-consider can guide diagnostic evaluation, treatment and monitoring of SAIDs

SAIDs are a group of multi-system disorders caused by dysfunction in the innate immune system. A number of these SAIDs are mediated by a cytokine called interleukin-1 (IL-1), including the cryopyrin-associated periodic syndromes (CAPS), tumor necrosis factor receptor-associated periodic syndrome (TRAPS), mevalonate kinase deficiency (MKD), and deficiency of the IL-1 receptor antagonist (DIRA).

1 Nov 2022

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

Many medical devices for treating heart failure generate nonphysiological shear flow. This can trigger the destruction of red blood cells after implantation of ventricular assist devices (VADs), artificial heart valves, vascular stents, or interventional thrombectomy devices.

1 Nov 2022

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New research discussed the structure and life cycle of respiratory syncytial virus (RSV), the current research on the treatment and prevention of RSV infections, and the advancements in RSV mRNA vaccine technology after the surge in vaccine research during the COVID-19 pandemic.

1 Nov 2022

New analysis on the risk for myocarditis or pericarditis after mRNA COVID-19 vaccination

A comprehensive review and meta-analysis of published research confirm that young adults (40 years old and younger) have a slightly elevated risk for myocarditis or pericarditis after mRNA COVID-19 vaccination.

1 Nov 2022

Research News and Research

New control system could be used to finely tune the production of useful proteins

Researchers offer new insights into the neurobiological basis of autism spectrum disorders

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

First pig-to-human cardiac transplant alters heart's electrical signals

Study provides a broader picture of consumer dining behavior during COVID-19 pandemic

New research lays the foundation for more effectively treating pediatric brain tumor

New method helps gain fundamental insights into ribosome function

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Rutgers study finds substantial inequities in access to specialty epilepsy care in New Jersey

The maternal RSV vaccine from Pfizer protects newborns against severe illness

New review elucidates current treatment approaches for myelodysplastic syndromes

UT Southwestern study uncovers a causative signaling pathway in breast cancer

First preclinical model to study the pathobiology of appendiceal cancer

Social and economic inequality associated with differences in children's brain connections

Study provides insight into how sleep and wakefulness regulate inhibitory synapses

Hospital investigated for allegedly denying an emergency abortion after patient’s water broke

EULAR points-to-consider can guide diagnostic evaluation, treatment and monitoring of SAIDs

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New analysis on the risk for myocarditis or pericarditis after mRNA COVID-19 vaccination

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