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First Edition: January 10, 2014

Today's headlines include reports about Maryland's plan to reduce hospital spending.

10 Jan 2014

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

Findings of a preliminary study published in The Lancet Respiratory Medicine suggest that a patient’s own bone-marrow stromal (stem) cells could be used to treat multidrug-resistant (MDR) and extensively-drug (XDR) tuberculosis.

10 Jan 2014

IBM and OhioHealth collaborate to aid in prevention of infections in hospitals

OhioHealth and IBM today announced a collaboration to aid in the prevention of infections using a first-of-a-kind network of wireless sensors and real-time Big Data analytics that measure hand-washing practices.

10 Jan 2014

Viewpoints: Don't blame insurers for health system problems; Obama's 'management failure;' Texas abortion case heads to court

[The] problem with the Affordable Care Act isn't the insurance industry. In fact, the main benefits of nationalized health care can be achieved in systems with hundreds, even thousands, of for-profit insurers. ...

10 Jan 2014

PaxVax reports interim data from Phase 3 cholera challenge study of PXVX0200

PaxVax Inc, which develops and commercializes innovative vaccines against infectious diseases in a socially responsible manner, today announced interim data from a Phase 3 cholera challenge study of its single-dose oral cholera vaccine candidate, PXVX0200 (also known as CVD 103-HgR). Trial investigators compared the rate of diarrhea in participants vaccinated with PXVX0200 to the rate in participants who had received placebo.

10 Jan 2014

Sutter Davis Hospital receives Malcolm Baldrige National Quality Award for excellent performance

Sutter Davis Hospital (SDH) has become the first organization in the greater Sacramento area and the smallest hospital ever to receive the Malcolm Baldrige National Quality Award, the nation's only Presidential honor that recognizes performance excellence in education, healthcare and business organizations.

10 Jan 2014

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

Neurovance Inc. today announced interim results from its phase 2a pilot study of EB-1020 SR in adult patients with all subtypes of ADHD. With the four week trial fully enrolled and dosing completed in the majority of patients, the results indicate a statistically significant improvement in ADHD symptoms.

10 Jan 2014

AOM associated with significant increases in direct costs incurred by consumers, health care system

Acute otitis media, or ear infection, is the most common ailment among kids of preschool age and younger in the U.S., primarily because these children have immature middle-ear drainage systems, higher exposure to respiratory illnesses and undeveloped immune systems.

10 Jan 2014

Research: SLPI protein produced by body in response to injury plays vital role in patients with ALF

Findings published in the American Association for the Study of Liver Diseases journal, Hepatology, indicate that infection, the commonest cause of mortality in patients with acute liver failure, may be decreased by inhibiting the activity of a protein found in saliva called SLPI.

10 Jan 2014

Teens with a history of concussions more likely to suffer from depression

Teens with a history of concussions are more than three times as likely to suffer from depression as teens who have never had a concussion, finds a new study in the Journal of Adolescent Health.

10 Jan 2014

Bipartisan commission: States should lead efforts to cut health costs

State leaders have significant power to curb rising health care costs and they should lead the effort, advises a commission co-chaired by two former governors. Meanwhile, a Massachusetts state report concludes that more than a third of health-care spending in that state each year may be wasteful.

10 Jan 2014

Aetna is helping to reverse abuse of prescription painkillers

Abuse of prescription painkillers, known as opioids, is a widespread and growing problem in the United States. The epidemic adds billions of dollars to health care, work place and criminal justice costs each year.

10 Jan 2014

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types, transforming - among many other forms -- into compressed discs capable of going through capillaries with diameters smaller than the blood cell itself.

10 Jan 2014

Prenatal exposure to maternal stress hormones predicts nicotine dependence for daughters

Tobacco smoking by pregnant women has long been viewed as a public health risk because of smoking's adverse effects on the development of a fetus.

10 Jan 2014

Discovery opens new therapeutic avenue for chronic skin condition affecting millions

Researchers from the La Jolla Institute for Allergy and Immunology have revealed a critical player in the cellular interactions leading to eczema - a chronic inflammatory skin condition affecting more than 14 million U.S. children and adults.

10 Jan 2014

Longer reads: Hospice drains Medicare; false Obamacare 'horror stories;' growing up without vaccines

Hospice patients are expected to die: The treatment focuses on providing comfort to the terminally ill, not finding a cure. To enroll a patient, two doctors certify a life expectancy of six months or less. But over the past decade, the number of "hospice survivors" in the United States has risen dramatically, in part because hospice companies earn more by recruiting patients who aren't actually dying, a Washington Post investigation has found. Healthier patients are more profitable because they require fewer visits and stay enrolled longer (Peter Whoriskey and Dan Keating, 12/26).

9 Jan 2014

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.

9 Jan 2014

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Gastric bypass surgery is a type of bariatric operation that results in weight loss and stimulates metabolic effects that treat diabetes and other cardiovascular risk factors such as diabetes, high cholesterol, and hypertension.

9 Jan 2014

Trevena doses first patient in TRV027 Phase 2b trial for acute heart failure

Trevena, Inc., a clinical stage pharmaceutical company involved in the discovery and development of G-protein coupled receptor biased ligands, announced today initiation of dosing in BLAST-AHF, the Company's randomized, multi-center Phase 2b trial of TRV027 in patients with acute heart failure.

9 Jan 2014

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Biogen Idec and Sangamo BioSciences, Inc. announced today an exclusive worldwide collaboration and license agreement focused on the development of therapeutics for hemoglobinopathies, inherited conditions that result from the abnormal structure or underproduction of hemoglobin.

9 Jan 2014

Hospital News and Research

First Edition: January 10, 2014

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

IBM and OhioHealth collaborate to aid in prevention of infections in hospitals

Viewpoints: Don't blame insurers for health system problems; Obama's 'management failure;' Texas abortion case heads to court

PaxVax reports interim data from Phase 3 cholera challenge study of PXVX0200

Sutter Davis Hospital receives Malcolm Baldrige National Quality Award for excellent performance

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

AOM associated with significant increases in direct costs incurred by consumers, health care system

Research: SLPI protein produced by body in response to injury plays vital role in patients with ALF

Teens with a history of concussions more likely to suffer from depression

Bipartisan commission: States should lead efforts to cut health costs

Aetna is helping to reverse abuse of prescription painkillers

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

Prenatal exposure to maternal stress hormones predicts nicotine dependence for daughters

Discovery opens new therapeutic avenue for chronic skin condition affecting millions

Longer reads: Hospice drains Medicare; false Obamacare 'horror stories;' growing up without vaccines

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Trevena doses first patient in TRV027 Phase 2b trial for acute heart failure

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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