Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Osteoporosis drug Raloxifene shown to be as effective as Tamoxifen in preventing invasive breast cancer

Initial results of the Study of Tamoxifen and Raloxifene, or STAR, show that the drug raloxifene, currently used to prevent and treat osteoporosis in postmenopausal women, works as well as tamoxifen in reducing breast cancer risk for postmenopausal women at increased risk of the disease.

18 Apr 2006

Researchers release results of (STAR) breast cancer prevention trial

Below are comments from Len Lichtenfeld, MD, American Cancer Society deputy chief medical officer, in response to the results of the STAR trial.

18 Apr 2006

Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy

Ultrasound provides a safe and accurate method of detecting breast cancers in pregnant women, as well as assessing response to chemotherapy, according to a study appearing in the April issue of Radiology.

13 Apr 2006

New risks identified after early breast cancer

A new study of women with early stage, localized breast cancer identifies new patterns and risk factors for invasive disease that may influence how patients are treated.

13 Apr 2006

Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy

The patient of a periodontist in private practice in New Orleans developed osteonecrosis of the jaw (ONJ), a condition that can cause severe, often irreversible and debilitating damage to the jaw, following periodontal surgical therapy.

11 Apr 2006

Estrogen-alone hormone therapy does not increase the risk of breast cancer in postmenopausal women

The results contrast with the previously reported WHI Estrogen plus Progestin Trial, which found an increase in breast cancer over about 5 years among those taking combined hormone therapy.

11 Apr 2006

Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ

A new study of women with early stage, localized breast cancer identifies new patterns and risk factors for invasive disease that may influence how patients are treated.

10 Apr 2006

Inflammation cuts both ways

Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder.

6 Apr 2006

Radiofrequency ablation is as effective as surgery for small liver tumors

Three-year data shows that radiofrequency ablation is as effective as surgical resection for overall survival and tumor recurrence, for the treatment of single small hepatocellular carcinoma in patients with liver cirrhosis, according to a study presented at the Society of Interventional Radiology's 31st Annual Scientific Meeting.

4 Apr 2006

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

The unchecked activity of a cell signaling pathway crucial in embryonic development and the liver's response to injury leads to liver cancer, researchers from Duke University Medical Center and John Hopkins University School of Medicine have found.

4 Apr 2006

Skin cancer facts

Up to two-thirds of all cancers may be prevented through dietary and lifestyle changes. In the case of skin cancer, this could not be more true.

4 Apr 2006

Omega-3 fatty acids inhibit the growth of liver cancer cells

Two new studies by a University of Pittsburgh research team suggest that omega-3 fatty acids - substances that are found in high concentrations in fish oils and certain seeds and nuts - significantly inhibit the growth of liver cancer cells.

3 Apr 2006

Underutilization of partial nephrectomy for localized renal cell carcinoma in the U.S.

In the past, the gold standard for the treatment of localized renal tumors has been radical nephrectomy. Over time however, experience with nephron sparing surgery and, now, laparoscopic approaches have demonstrated oncologic equipoise and may provide for an improved quality of life for patients as compared to those undergoing radical nephrectomy for localized renal masses.

31 Mar 2006

First trial to combine a biologic agent with a conventional chemotherapy agent for the treatment of ovarian cancer

Researchers found the addition of thalidomide to topotecan for the treatment of recurrent ovarian cancer significantly increases the response to therapy and the duration of progression free survival without additional toxicity.

28 Mar 2006

Not all breast cancers' risk are increased by Hormone Replacement Therapy

Recent research presented at EBCC-5 from the million women study found that taking Hormone Replacement Therapy (HRT) increased the risk of some types of breast cancer, but not others.

23 Mar 2006

Human papillomavirus may be a risk factor in developing squamous cell carcinoma

The study, published in the March 15 issue of the Journal of the National Cancer Institute, used new technology to detect antibodies from a strain of HPV on skin cancer samples.

20 Mar 2006

Thrombocytosis: A clinical marker of tumor aggressiveness in renal cell carcinoma

Molecular and serum markers of prognosis in renal cell carcinoma have remained elusive. In large part, tumor (TNM) stage, Fuhrman grade, and patient performance status have stood the test of time as the most valuable factors in predicting patient outcome following surgery.

15 Mar 2006

Carcinoma News and Research

Further Reading

Osteoporosis drug Raloxifene shown to be as effective as Tamoxifen in preventing invasive breast cancer

Researchers release results of (STAR) breast cancer prevention trial

Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy

New risks identified after early breast cancer

Oral post-surgical complications following the administration of bisphosphonates given for osteopenia related to malignancy

Estrogen-alone hormone therapy does not increase the risk of breast cancer in postmenopausal women

Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ

Inflammation cuts both ways

Radiofrequency ablation is as effective as surgery for small liver tumors

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

Skin cancer facts

Omega-3 fatty acids inhibit the growth of liver cancer cells

Underutilization of partial nephrectomy for localized renal cell carcinoma in the U.S.

First trial to combine a biologic agent with a conventional chemotherapy agent for the treatment of ovarian cancer

Not all breast cancers' risk are increased by Hormone Replacement Therapy

Human papillomavirus may be a risk factor in developing squamous cell carcinoma

Thrombocytosis: A clinical marker of tumor aggressiveness in renal cell carcinoma

Human papillomavirus infections and incidence of squamous cell and basal cell carcinomas of the skin

New vaccines will protect against cancer

Therapy for metastatic renal cell carcinoma remains inadequate

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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