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ICGC: New era of personalised medicine for cancer patients

Published online today in Nature, a paper authored by over 200 members of the International Cancer Genome Consortium describes the beginnings of a Brave New World, a new era of personalised medicine for cancer patients.

15 Apr 2010

Florida to enact health care legislation to improve access to ARV therapy

Florida is poised to enact health care legislation that would add clarity to existing state statutes by requiring that all state-regulated health plans include lifesaving antiretroviral (ARV) HIV/AIDS drugs on their drug formularies or preferred drug lists.

15 Apr 2010

Inflammasome components help protect against colitis

Particular components of inflammasomes-protein complexes needed for generating immune responses to pathogens and cellular damage-lessen the severity of colitis and colitis-associated colon cancer in mice, according to a study published online this week in the Journal of Experimental Medicine.

13 Apr 2010

National organizations, medical institutions join Lung Cancer Alliance to address nation's most lethal cancer

Today, Lung Cancer Alliance announced new additions to the growing list of supporters joining LCA in its "call to action" to devise a better public health strategy to address the nation's most lethal cancer.

13 Apr 2010

Oceana Therapeutics, Q-Med submit Solesta PMA application for treatment of fecal incontinence

Oceana Therapeutics and Q-Med AB today announced the filing of a Premarket Approval (PMA) application with the U.S. Food and Drug Administration (FDA) for Solesta® for the treatment of Fecal (or Bowel) Incontinence, a largely unsatisfied medical need afflicting millions of Americans.

12 Apr 2010

Modified ESD procedure can remove large ileal lipoma: Research article

Lipoma is relatively common in the colon but is less often in the small intestine. Most lipomas are incidentally detected at endoscopy and are usually small and asymptomatic. However, some of them can present with obstruction and/or intussusceptions. Surgical resection is commonly recommended to remove such significant lipomas with a limited pedicle and larger than 2 cm in size, as endoscopic resection may result in unfavorable complications such as intestinal perforations.

12 Apr 2010

Recql5 identified as a tumor suppressor in GI tract

Recql5 is a member of the mammalian RecQ helicase family. Genetic mutations that result in loss of RecQ helicase activity give rise to disorders that are associated with cancer predisposition and premature aging, such as Bloom, Werner, and Rothmund-Thomson syndromes. This class of enzymes is best known for their role in maintaining the integrity of the genome to prevent oncogenic mutations.

9 Apr 2010

Potential toxicity of zinc nanoparticles in sunscreen products

Scientists are reporting that particle size affects the toxicity of zinc oxide, a material widely used in sunscreens. Particles smaller than 100 nanometers are slightly more toxic to colon cells than conventional zinc oxide. Solid zinc oxide was more toxic than equivalent amounts of soluble zinc, and direct particle to cell contact was required to cause cell death. Their study is in ACS' Chemical Research in Toxicology, a monthly journal.

8 Apr 2010

Secretary of Health announces five health research grants to improve health of Pennsylvanians

Secretary of Health Everette James today announced five health research grants totaling approximately $20 million will be awarded from Pennsylvania's share of the national tobacco settlement for 2009-2010.

8 Apr 2010

NHS cancer patients to receive latest and best treatments available

Cancer patients on the National Health Service may soon be offered expensive life extending drugs which are currently denied to them. David Cameron has proposed on behalf of the Conservatives that the drugs that are licensed and prescribed by the health consultant of the patient should be made available to the cancer patient, irrespective of the NHS rationing.

5 Apr 2010

NewYork-Presbyterian Hospital installs high-tech imaging systems for heart and vascular surgeries

In a move that could change the way many patients undergo surgery, NewYork-Presbyterian Hospital has installed five state-of-the-art Siemens Artis zeego- medical imaging systems that provide faster, more accurate 3-D images of the body with a quality never before attainable.

3 Apr 2010

Cancer Prevention Coalition submits petition on imminent health hazard from hormonal meat

As reported in a March 18, New York Times editorial, "Honest Food Labels," FDA Commissioner, Margaret Hamburg, M.D., publicized letters to 17 food companies accusing them of -- "masking undesirable ingredients" -- in their products. She also emphasized the importance of "providing nutrition information that consumers can rely on."

3 Apr 2010

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Renuka Iyer, MD, of the Department of Medicine, and Dan Iancu, MD, of the Department of Pathology and Laboratory Medicine at Roswell Park Cancer Institute (RPCI) are studying how a new test called CellSearch could be used with standard radiographic methods to monitor treatment results in patients with locally advanced or metastatic gallbladder or biliary duct cancers. The goal of the study is to see if CellSearch could predict patient response to therapy earlier than traditional measures.

2 Apr 2010

Hospira reaches legal settlement with Sanofi-Aventis over oxaliplatin injection patent litigation

Hospira, Inc., the world leader in generic injectable pharmaceuticals, today announced it has reached a legal settlement with Sanofi-Aventis to resolve patent litigation concerning Hospira's U.S. sales of its oxaliplatin injection, a generic version of Sanofi-Aventis' oncolytic agent, Eloxatin®.

2 Apr 2010

APP, Fresenius Kabi and sanofi-aventis sign license and settlement agreements

Fresenius Kabi Pharmaceuticals Holding, Inc.,, the parent company of APP Pharmaceuticals, Inc., announced today that APP and other Fresenius Kabi companies have entered into license and settlement agreements with sanofi-aventis covering patents that apply to Eloxatin® (oxaliplatin injection and oxaliplatin for injection).

2 Apr 2010

ImmunoCellular Therapeutics files Annual Report with Securities and Exchange Commission for 2009

ImmunoCellular Therapeutics announced today that it has filed its Annual Report with the Securities and Exchange Commission for the period ended December 31, 2009 on Form 10-K.

1 Apr 2010

Combating immune suppressive cells in liver may prevent the spread of cancer: Study

Scientists have uncovered what could be a very important clue in answering one of the most perplexing questions about cancer: why does it spread to the liver more than any other organ? In a new research report published in the April 2010 issue of Journal of Leukocyte Biology, scientists from New York University describe experimental results suggesting that the immune system may be the reason.

1 Apr 2010

Indispensable role of Mindin in innate and adaptive immunity

Mindin has an indispensable role in both innate and adaptive immunity. A research group in China investigated regulation of mindin expression and the signaling pathway involved. mRNA expression of mindin was upregulated during dextran sulfate sodium induced mouse intestinal inflammation. Stimulation with CpG-ODN (a known TLR-9 ligand) induced upregulation of mindin expression in RAW 264.7 cells and significantly increased the NF-κB-luciferase activity in vitro.

31 Mar 2010

Dr Patel ignored advice from colleagues

The charges of manslaughter that Dr Patel has been facing over three patients he had operated on between 2003 and 2005 are now on trial in the Supreme Court in Brisbane. The patients were Mervyn John Morris, 75 , Ames Edward Phillips, 46, and Geradus Wihelmus Gosewinus Kemps, 77. Dr Patel is also charged with one grievous bodily harm case besides these three manslaughter charges to Ian Rodney Vowles, 62.

30 Mar 2010

Two-drug combination destroys precancerous colon polyps

A two-drug combination destroys precancerous colon polyps with no effect on normal tissue, opening a new potential avenue for chemoprevention of colon cancer, a team of scientists at The University of Texas M. D. Anderson Cancer Center reports in the advance online edition of the journal Nature.

29 Mar 2010

Colon News and Research

ICGC: New era of personalised medicine for cancer patients

Florida to enact health care legislation to improve access to ARV therapy

Inflammasome components help protect against colitis

National organizations, medical institutions join Lung Cancer Alliance to address nation's most lethal cancer

Oceana Therapeutics, Q-Med submit Solesta PMA application for treatment of fecal incontinence

Modified ESD procedure can remove large ileal lipoma: Research article

Recql5 identified as a tumor suppressor in GI tract

Potential toxicity of zinc nanoparticles in sunscreen products

Secretary of Health announces five health research grants to improve health of Pennsylvanians

NHS cancer patients to receive latest and best treatments available

NewYork-Presbyterian Hospital installs high-tech imaging systems for heart and vascular surgeries

Cancer Prevention Coalition submits petition on imminent health hazard from hormonal meat

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Hospira reaches legal settlement with Sanofi-Aventis over oxaliplatin injection patent litigation

APP, Fresenius Kabi and sanofi-aventis sign license and settlement agreements

ImmunoCellular Therapeutics files Annual Report with Securities and Exchange Commission for 2009

Combating immune suppressive cells in liver may prevent the spread of cancer: Study

Indispensable role of Mindin in innate and adaptive immunity

Dr Patel ignored advice from colleagues

Two-drug combination destroys precancerous colon polyps

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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