Colon News and Research

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Elevated blood glucose levels increase early-onset colorectal cancer risk

Study finds elevated blood glucose levels significantly increase the risk of colorectal cancer, with early-onset cases showing a stronger association. No non-linear relationships were detected.

8 Oct 2024

New insights on 5-fluorouracil's mechanism in different cancers

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

7 Oct 2024

Researchers develop technology to change protein identity in vivo

Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins. The innovation, published in Nature Communications on October 2, allowed researchers to target mouse tumors with a protein and then transport that protein out of the body.

3 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

New insights improve genetic classification for hereditary colorectal cancer

The genetic confirmation of a suspected diagnosis of "hereditary colorectal cancer" is of great importance for the medical care of affected families.

1 Oct 2024

Traditional Chinese medicine shows potential in cancer treatment

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, all of which have significantly contributed to improving patient survival.

1 Oct 2024

Researchers identify a protein that recharges T cells for long-lasting cancer remission

Research shows Fc–IL-4 revitalizes exhausted CD8+ T cells, boosting antitumor responses and highlighting the potential of combining type 1 and type 2 immunity.

30 Sep 2024

Estrogen found to promote tumor growth in breast cancers without receptors

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers.

27 Sep 2024

Researchers explore new metabolic pathway to fight cancer

When an aggressive cancer launches an invasion on the human body, anything that can be done to slow down or better understand that fast-paced assault is going to be a bonus.

26 Sep 2024

Study reveals anti-tumor properties of food antigens

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative medical sciences (IMS) in Japan have discovered that food antigens like milk proteins help keep tumors from growing in our guts, specifically the small intestines.

23 Sep 2024

Excess body weight at first cancer diagnosis increases risk of second cancer

Adults with excess body weight at their first cancer diagnosis face a higher risk of developing a second primary cancer, particularly those related to obesity, according to a recent study. The research emphasizes the need for survivorship guidelines targeting weight management.

22 Sep 2024

Affordable Care Act boosts colon cancer care for underserved groups in Pennsylvania

The Affordable Care Act (ACA) has led to increased guideline-concordant care for colon cancer among non-white patients, patients from rural areas, and patients from the most deprived neighborhoods in Pennsylvania, according to results presented at the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held September 21-24, 2024.

21 Sep 2024

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Researchers examine how different dietary components affect the gut microbiome and development of non-communicable diseases.

20 Sep 2024

Access to accredited hospitals improves cancer care outcomes for vulnerable patients

Vulnerable patients facing social, environmental, and economic disadvantages often experience worse cancer outcomes than other groups.

19 Sep 2024

Researchers seek to revolutionize rectal cancer treatment with AI

With a new four-year, $1.14 million grant from the U.S. Department of Veterans Affairs, researchers at Case Western Reserve University and the Louis Stokes Cleveland VA Medical Center, will use artificial intelligence (AI) to determine the best personalized treatment for Veterans with rectal cancer.

19 Sep 2024

Humor helps reduce avoidance of colorectal cancer information

Colorectal cancer (CRC) is no laughing matter. It's the second-leading cause of cancer deaths globally, according to the World Health Organization.

17 Sep 2024

High-dose vitamin D3 cannot be recommended as treatment for metastatic colon cancer

A double-blind randomized phase 3 clinical trial led by Dana-Farber Cancer Institute researchers and conducted across several hundred cancer centers in the U.S. tested the addition of high-dose vitamin D3 to standard treatment for patients with untreated metastatic colorectal cancer.

16 Sep 2024