Biochemistry News and Research

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Case Western Reserve University receives grant to research on glucose-responsive insulin

Case Western Reserve University's School of Medicine has received a nearly $1 million grant from The Leona M. and Harry B. Helmsley Charitable Trust's Type 1 diabetes program.

15 Mar 2013

Synthesis & Solid State Pharmaceutical Centre: an interview with Dr Mary Shire, University of Limerick

This is a new research centre led by the University of Limerick that supports the pharmaceutical sector in Ireland. The centre will carry out research on the key aspects of what it takes to synthesise the pharmaceutically active molecule to isolate a pure material and to formulate this into a medicine.

14 Mar 2013

Scientists sign licensing agreement for anticancer substances

Most cancer patients die of the disease because tumor cells spread to other sites in the body and form new tumors, so-called metastases.

14 Mar 2013

MiR-198 controls migration of skin cells necessary for wounds to close and heal

Patients with diseases such as diabetes suffer from painful wounds that take a long time to heal making them more susceptible to infections that could even lead to amputations. A*STAR's discovery paves the way for therapeutics to improve healing of such chronic wounds, which are a significant burden to patients.

11 Mar 2013

Researchers identify new mechanism in onset of motor neuron diseases

The British astrophysicist Stephen Hawking is likely to be the world's most famous person living with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. ALS is a progressive disease affecting motor neurons, nerve cells that control muscle function, and nearly always leads to death.

11 Mar 2013

UT Southwestern researcher to receive March of Dimes Prize in Developmental Biology

Dr. Eric Olson, chairman of molecular biology at UT Southwestern Medical Center, is the 2013 recipient of the March of Dimes Prize in Developmental Biology for identifying key genetic pathways in the formation of the heart and other muscles.

11 Mar 2013

Researchers identify enzymes that can regulate activity of medically important proteins

Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology from the University of Zurich have identified enzymes that can regulate the activity of medically important proteins.

11 Mar 2013

New technology can turn off genes more precisely, say UCSF researchers

Scientists at UC San Francisco have found a more precise way to turn off genes, a finding that will speed research discoveries and biotech advances and may eventually prove useful in reprogramming cells to regenerate organs and tissues.

8 Mar 2013

Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones

Today, the Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones: the renewal of the partnership agreement for an extended period of 10 years, and the expansion of the Nordic EMBL network with the official opening of the Danish Research Institute of Translational Neuroscience (DANDRITE) at Aarhus University, which will become its Danish node.

6 Mar 2013

tRNA synthetases play unexpected and critical role in cancer metastasis

Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected - and critical - additional role in cancer metastasis in a study conducted collaboratively in the labs of Karen Lounsbury, Ph.D., University of Vermont professor of pharmacology, and Christopher Francklyn, Ph.D., UVM professor of biochemistry.

5 Mar 2013

Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

Sanford-Burnham Medical Research Institute and 60- Pharmaceuticals, LLC, have entered into a partnership to test furin, a human proteinase, as a drug target for the treatment of dengue fever, one of the most common infectious diseases in the tropics and subtropics.

5 Mar 2013

Researchers discover new candidate disease proteins for neurodegenerative disorders

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders.

4 Mar 2013

Study identifies two gene mutations that lead to death of nerve cells in ALS

A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

4 Mar 2013

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.

2 Mar 2013

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus.

2 Mar 2013

Study shows triple-negative breast cancer cells missing key enzyme

A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain - providing insight into potential therapeutic targets to treat the aggressive cancer.

2 Mar 2013

Freie Universität Berlin research team examines thermoresponsive nanogels for treatment of cancer

The German Federal Ministry of Education and Research is supporting a new research group at Freie Universität Berlin that is investigating so-called thermoresponsive nanogels.

27 Feb 2013

Researchers map complex interactions of proteins that control inflammation

Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not understood the mechanisms that underlie it.

25 Feb 2013

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

The University of Colorado (CU) has signed exclusive, worldwide licensing and collaboration agreements with rare-disease research-and-development firm Orphan Technologies Ltd to develop an enzyme replacement therapy for Cystathionine Beta-Synthase (CBS) -deficient homocystinuria, a rare, inherited metabolic disease that is often fatal at a young age.

25 Feb 2013

Biochemistry News and Research

Case Western Reserve University receives grant to research on glucose-responsive insulin

Synthesis & Solid State Pharmaceutical Centre: an interview with Dr Mary Shire, University of Limerick

Scientists sign licensing agreement for anticancer substances

MiR-198 controls migration of skin cells necessary for wounds to close and heal

Researchers identify new mechanism in onset of motor neuron diseases

UT Southwestern researcher to receive March of Dimes Prize in Developmental Biology

Researchers identify enzymes that can regulate activity of medically important proteins

New technology can turn off genes more precisely, say UCSF researchers

Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones

tRNA synthetases play unexpected and critical role in cancer metastasis

Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

Researchers discover new candidate disease proteins for neurodegenerative disorders

Study identifies two gene mutations that lead to death of nerve cells in ALS

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Study shows triple-negative breast cancer cells missing key enzyme

Freie Universität Berlin research team examines thermoresponsive nanogels for treatment of cancer

Researchers map complex interactions of proteins that control inflammation

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

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